YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: STI1

General Information:
Name(s) found: STI1 / YOR027W [SGD]
Description(s) found:
Found 29 descriptions.
SHOW ALL
  • Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones; activates the ATPase activity of Ssa1p; homolog of mammalian Hop protein [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 589 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IPILink to PubMed article]
    Biological Process: protein folding [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: chaperone inhibitor activity [IDALink to PubMed articleLink to PubMed article]
    chaperone activator activity [IDALink to PubMed article]
    Hsp90 protein binding [IDALink to PubMed articleLink to PubMed article]
    Hsp70 protein binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLTADEYKQ QGNAAFTAKD YDKAIELFTK AIEVSETPNH VLYSNRSACY TSLKKFSDAL  60
   61 NDANECVKIN PSWSKGYNRL GAAHLGLGDL DEAESNYKKA LELDASNKAA KEGLDQVHRT 120
  121 QQARQAQPDL GLTQLFADPN LIENLKKNPK TSEMMKDPQL VAKLIGYKQN PQAIGQDLFT 180
  181 DPRLMTIMAT LMGVDLNMDD INQSNSMPKE PETSKSTEQK KDAEPQSDST TSKENSSKAP 240
  241 QKEESKESEP MEVDEDDSKI EADKEKAEGN KFYKARQFDE AIEHYNKAWE LHKDITYLNN 300
  301 RAAAEYEKGE YETAISTLND AVEQGREMRA DYKVISKSFA RIGNAYHKLG DLKKTIEYYQ 360
  361 KSLTEHRTAD ILTKLRNAEK ELKKAEAEAY VNPEKAEEAR LEGKEYFTKS DWPNAVKAYT 420
  421 EMIKRAPEDA RGYSNRAAAL AKLMSFPEAI ADCNKAIEKD PNFVRAYIRK ATAQIAVKEY 480
  481 ASALETLDAA RTKDAEVNNG SSAREIDQLY YKASQQRFQP GTSNETPEET YQRAMKDPEV 540
  541 AAIMQDPVMQ SILQQAQQNP AALQEHMKNP EVFKKIQTLI AAGIIRTGR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) HSC82 HSP82 STI1
    View Details Krogan NJ, et al. (2006) AHA1 BUD3 CNS1 CPR6 DIG2 DNM1 DSF1, YNR073C FRT2 GPA2 HOM6 HSC82 HSP104 HSP82 MBB1 MRPL50 PAM1 PPT1 QNS1 RMD8 RTS1 SMT3 STI1 STP4 TDH1 UTP20 YBL104C
    View Details Ho Y, et al. (2002) ACC1 ADR1 ARP2 ATP3 AVO1 BFR2 BIR1 BNA5 BTN2 BUD7 CCR4 CCT2 CCT3 CCT5 CCT6 CDC36 CDC39 CDC53 CDC7 CLU1 COP1 COR1 CPA2 CPR6 CTR1 CYS4 DEF1 DHH1 DMA1 DMA2 DPB2 DSS1 EAP1 ECM10 ERG1 FOL2 FUN12 GAL7 GDT1 GPH1 IDH1 IDH2 ILV2 JIP3 LHS1 LSC1 LST8 LYS12 MDN1 MEC1 MEH1 MET16 MKK2 MKT1 NAS6 NOG2 NPA3 NUT1 PDC5 PDC6 PDX1 PEX19 PGM2 PHO85 PHO86 PIL1 POP2 POR1 PRB1 PRE3 PRP4 PST2 PUF3 QCR2 RNQ1 RPC19 RPN1 RPN11 RPN12 RPN14 RPN3 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT2 RPT3 RPT4 RPT5 RRP3 RVB1 SAH1 SAR1 SEC27 SEC28 SER1 SIP1 SIS1 SKP1 SLC1 SLT2 SLX1 SMK1 SRP54 SRV2 SSL2 STI1 TCP1 TEM1 TFC7 THI3 TPS1 UBA1 UBC12 UBI4 UBR1 VAC14 VMA8 YBT1 YCR076C YDR306C YER066C-A YER077C YGR266W YKR051W YKU80 YLR271W YML020W YNL311C YPR003C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen NSE4 STI1 2 Unpublished Fields Lab Data
    View Screen PAC1 STI1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data STI1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..147] PSI-BLAST 138.07631 Hop
    2 View Details [148..224] deduced N/A No confident structure predictions are available.
    3 View Details [225..341] PSI-BLAST 226.9794 Hop
    4 View Details [342..391] PSI-BLAST 226.9794 Hop
    5 View Details [392..589] PSI-BLAST 118.679424 Protein phosphatase 5


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle