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Protein Overview: MET16

General Information:
Name(s) found: MET16 / YPR167C [SGD]
Description(s) found:
Found 30 descriptions.
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  • 3'-phosphoadenylsulfate reductase, reduces 3'-phosphoadenylyl sulfate to adenosine-3',5'-bisphosphate and free sulfite using reduced thioredoxin as cosubstrate, involved in sulfate assimilation and methionine metabolism [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 261 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [TASLink to PubMed article]
    intracellular [TASLink to PubMed article]
    Biological Process: response to drug [IMPLink to PubMed article]
    sulfate assimilation [TASLink to PubMed article]
    methionine metabolic process [IMPLink to PubMed article]
    Molecular Function: phosphoadenylyl-sulfate reductase (thioredoxin) activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTYHLNNDI IVTQEQLDHW NEQLIKLETP QEIIAWSIVT FPHLFQTTAF GLTGLVTIDM  60
   61 LSKLSEKYYM PELLFIDTLH HFPQTLTLKN EIEKKYYQPK NQTIHVYKPD GCESEADFAS 120
  121 KYGDFLWEKD DDKYDYLAKV EPAHRAYKEL HISAVFTGRR KSQGSARSQL SIIEIDELNG 180
  181 ILKINPLINW TFEQVKQYID ANNVPYNELL DLGYRSIGDY HSTQPVKEGE DERAGRWKGK 240
  241 AKTECGIHEA SRFAQFLKQD A

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ATP3 AVO1 CCT5 CLU1 DHH1 DPB2 FUN12 GAL7 GPH1 IDH1 ILV2 MET16 MKK2 NOG2 NPA3 PDX1 PHO85 PUF3 RPN12 SIS1 SLX1 SRP54 STI1 TEM1 TFC7 VMA8 YER077C YGR266W YKR051W YKU80 YLR271W YPR003C

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MET16 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..261] PSI-BLAST 220.035458 Phosphoadenylyl sulphate (PAPS) reductase


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.75

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle