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Protein Overview: YND1

General Information:
Name(s) found: YND1 / YER005W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Apyrase with wide substrate specificity, involved in preventing the inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates which are inhibitors of glycotransferases; partially redundant with Gda1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 630 amino acids

    Gene Ontology:
    Cellular Component: Golgi apparatus [IDALink to PubMed article]
    COPI-coated vesicle [IDALink to PubMed article]
    Biological Process: protein amino acid glycosylation [IMPLink to PubMed article]
    Molecular Function: nucleoside-diphosphatase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIENTNDRF GIVIDAGSSG SRIHVFKWQD TESLLHATNQ DSQSILQSVP HIHQEKDWTF  60
   61 KLNPGLSSFE KKPQDAYKSH IKPLLDFAKN IIPESHWSSC PVFIQATAGM RLLPQDIQSS 120
  121 ILDGLCQGLK HPAEFLVEDC SAQIQVIDGE TEGLYGWLGL NYLYGHFNDY NPEVSDHFTF 180
  181 GFMDMGGAST QIAFAPHDSG EIARHRDDIA TIFLRSVNGD LQKWDVFVST WLGFGANQAR 240
  241 RRYLAQLINT LPENTNDYEN DDFSTRNLND PCMPRGSSTD FEFKDTIFHI AGSGNYEQCT 300
  301 KSIYPLLLKN MPCDDEPCLF NGVHAPRIDF ANDKFIGTSE YWYTANDVFK LGGEYNFDKF 360
  361 SKSLREFCNS NWTQILANSD KGVYNSIPEN FLKDACFKGN WVLNILHEGF DMPRIDVDAE 420
  421 NVNDRPLFQS VEKVEERELS WTLGRILLYA SGSILAGNDD FMVGIAPSER RTKLTGKKFI 480
  481 PGKLLESDQL RKQSSSLSNK GFLMWFAIIC CIFYLIFHRS HIIRRRFSGL YNITKDFKTG 540
  541 IRRRLKFLRR SDPFSRLEEG ELGTDVDGFK DVYRMKSSSM FDLGKSSATM QREHEPQRTA 600
  601 SQSANLAPSN LRPAFSMADF SKFKDSRLYD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) GDA1 YND1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YND1 Huh WK, et al. (2003)
    View Data YND1 and COP1 Huh WK, et al. (2003)
    View Data YND1 and ANP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..499] Pfam 287.420216 GDA1/CD39 (nucleoside phosphatase) family No confident structure predictions are available.
    2 View Details [500..630] deduced N/A No confident structure predictions are available.
    3 View Details [384..450] MSA 4.120996 View MSA. No confident structure predictions are available.
    4 View Details [451..630] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transporter activity
    		•  2.6067350860805 bayes_pls_golite062009
  • binding
    		•  1.67810028738512 bayes_pls_golite062009
  • kinase activity
    		•  1.49017495306118 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  1.41202247176912 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.17094423081025 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.918413613159579 bayes_pls_golite062009
  • protein binding
    		•  0.909114722614987 bayes_pls_golite062009
  • peptide binding
    		•  0.512219022453579 bayes_pls_golite062009
  • hexokinase activity
    		•  0.3464071310254 bayes_pls_golite062009
  • catalytic activity
    		•  0.308539563780047 bayes_pls_golite062009
  • structural molecule activity
    		•  0.27696059113386 bayes_pls_golite062009
  • protein kinase activity
    		•  0.273427627634136 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.157726298952452 bayes_pls_golite062009
  • glucokinase activity
    		•  0.0827631486617343 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0562867443774764 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.0272188887044016 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle