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Protein Overview: EGD2

General Information:
Name(s) found: EGD2 / YHR193C [SGD]
Description(s) found:
Found 29 descriptions.
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  • Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) involved in protein sorting and translocation, associated with cytoplasmic ribosomes [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 174 amino acids

    Gene Ontology:
    Cellular Component: nascent polypeptide-associated complex [IDALink to PubMed article]
    Biological Process: 'de novo' cotranslational protein folding [IPILink to PubMed article]
    Molecular Function: unfolded protein binding [IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAIPENANV TVLNKNEKKA RELIGKLGLK QIPGIIRVTF RKKDNQIYAI EKPEVFRSAG  60
   61 GNYVVFGEAK VDNFTQKLAA AQQQAQASGI MPSNEDVATK SPEDIQADMQ AAAEGSVNAA 120
  121 AEEDDEEGEV DAGDLNKDDI ELVVQQTNVS KNQAIKALKA HNGDLVNAIM SLSK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BTT1 EGD1 EGD2
    View Details (MIPS) Mewes HW, et al. (2004) EGD1 EGD2
    View Details Krogan NJ, et al. (2006) BTT1 CAF130 EGD1 EGD2 PLC1 YJR011C
    View Details Ho Y, et al. (2002) ABP1 ACO1 AHA1 AIM41 ALA1 ARP2 ATP4 AXL1 BCK1 BUD14 CAR2 CCT6 CDC14 COR1 CPR6 CRZ1 CYS4 DBF20 DCP1 DCP2 DNM1 EDC3 EDE1 EGD2 ENP1 ERB1 FOL2 GAL7 GAS1 GCN3 GND1 GPH1 GUS1 HAS1 HHF1, HHF2 HRR25 HSP104 HXT7 HYP2 IDH1 IDH2 ILV5 IPP1 KIC1 KIN2 LHS1 LOC1 LSP1 LTV1 LYS12 MDH1 MDS3 MET6 MGE1 MKK2 MKT1 MOB1 MRT4 MUB1 NOC2 NOC3 NOG1 NSA1 NUG1 OYE2 PDC6 PEX19 PIL1 PIN4 PMA1 PRP43 PTC4 PUF3 QCR2 RCN2 RIO2 RPB10 RPC19 RPM2 RPN6 RPT3 SAH1 SAP185 SAP190 SAS10 SCS2 SEC2 SEC23 SEC53 SES1 SFB3 SGM1 SIS1 SIT4 SKG3 SLT2 SMK1 SPB4 SSQ1 TIF1, TIF2 TIF6 TMA19 TSR1 UBR2 VMA4 YBR225W YER138C YTM1
    View Details Qiu et al. (2008) BTT1 EGD1 EGD2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SPT21 EGD2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data EGD2 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] Pfam 25.107905 NAC domain No confident structure predictions are available.
    2 View Details [115..174] Pfam 3.0 UBA/TS-N domain No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle