Protein Overview: SES1

General Information:
Name(s) found:	SES1 / YDR023W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|642295\|emb\|CAA87802.1\| Ses1p [Saccharomyces cerevisiae] [NCBI NR] gi\|6320226\|ref\|NP_010306.1\| Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex2 [NCBI NR] gi\|1711650\|sp\|P07284.2\|SYSC_YEAST RecName: Full=Seryl-tRNA synthetase, cytoplasmic; AltName: Full=Seryl-tRNA(Ser/Sec) synthetase; AltName: Full=Serine--tRNA ligase; Short=SerRS [NCBI NR] gi\|1431454\|emb\|CAA98844.1\| SES1 [Saccharomyces cerevisiae] [NCBI NR] gi\|1216231\|emb\|CAA65216.1\| seryl-tRNA synthetase [Saccharomyces cerevisiae] [NCBI NR] pir\|\|YSBYC serine-tRNA ligase (EC 6.1.1.11), cytosolic - yeast (Saccharomyces cerevisiae) [NCBI NR] Seryl-tRNA synthetase, cytoplasmic OS=Saccharomyces cerevisiae GN=SES1 PE=1 SV=2 [Swiss-Prot] SES1 Seryl-tRNA synthetase, cytosolic [mips] Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p [SGD] SES1, Chr IV from 489503-490891 [yeast_orfs2] Chr IV from 489503-490891 [yeastorf3.fasta] (P07284) Seryl-tRNA synthetase, cytoplasmic (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS) [4932.FASTACCERV.txt] SES1 SGDID:S0002430, Chr IV from 489504-490892, Verified ORF [yeastflysequest.fasta] Ses1p [Saccharomyces cerevisiae]gi\|1216231\|emb\|CAA65216.1\| seryl-tRNA synthetase [Saccharomyces cerevisiae]gi\|1431454\|emb\|CAA98844.1\| SES1 [Saccharomyces cerevisiae]gi\|642295\|emb\|CAA87802.1\| Ses1p [Saccharomyces cerevisiae]gi\|1070526\|pir\|\|YSBYC serine [nrdb_11152004_Chlamydomonas] SES1 SGDID:S000002430, Chr IV from 489504-490892, Verified ORF, "Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine s [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] SES1 SGDID:S000002430, Chr IV from 489505-490893, Verified ORF, "Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine s [yeast-contam.fasta] SES1 SGDID:S000002430, Chr IV from 489506-490894, Verified ORF, "Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine s [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] Seryl-tRNA synthetase, cytoplasmic (Serine--tRNA ligase) (SerRS) [nr-271106-contam.fasta] Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p; Ses1p [Saccharomyces cer [nr-271106-contam.fasta] SES1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] seryl-tRNA synthetase [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Ses1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] SES1 SGDID:S000002430, Chr IV from 489506-490894, Verified ORF, "Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p" [yeast-bovrabprots.fasta] SES1 SGDID:S000002430, Chr IV from 489505-490893, Verified ORF, "Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p" [yeast-contam_custom.fasta] [chemostatdb.fasta] Serine--tRNA ligase, cytoplasmic OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SES1 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] SES1 SGDID:S000002430, Chr IV from 489508-490896, Genome Release 64-1-1, Verified ORF, "Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p" [yeast-030211-contam.fasta] SES1 SGDID:S000002430, Chr IV from 489508-490896, Genome Release 64-2-1, Verified ORF, "Cytosolic seryl-tRNA synthetase; class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p" [20141208_orf_trans.fasta] TR2005\|c0_g1_i1\|g.1487 ORF TR2005\|c0_g1_i1\|g.1487 TR2005\|c0_g1_i1\|m.1487 type:complete len:463 (+) TR2005\|c0_g1_i1:31-1419(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] TR3908\|c0_g1_i1\|g.2633 ORF TR3908\|c0_g1_i1\|g.2633 TR3908\|c0_g1_i1\|m.2633 type:complete len:463 (+) TR3908\|c0_g1_i1:29-1417(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YDR023W SGDID:S000002430, Chr IV from 489508-490896, Genome Release 64-1-1, Verified ORF, "Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_386\|g.355 ORF asmbl_386\|g.355 asmbl_386\|m.355 type:complete len:463 (+) asmbl_386:23-1411(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] asmbl_805\|g.573 ORF asmbl_805\|g.573 asmbl_805\|m.573 type:complete len:463 (+) asmbl_805:23-1411(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_386\|g.516 ORF ID=asmbl_386\|g.516 ID=asmbl_386\|m.516 type:complete len:463 (+) ID=asmbl_386:23-1411(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta] ID=asmbl_809\|g.251 ORF ID=asmbl_809\|g.251 ID=asmbl_809\|m.251 type:complete len:463 (+) ID=asmbl_809:23-1411(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	462 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA ]
Biological Process:	seryl-tRNA aminoacylation [IDA]
Molecular Function:	serine-tRNA ligase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLDINQFIED KGGNPELIRQ SQKARNASVE IVDEIISDYK DWVKTRFELD ELNKKFNKLQ  60
   61 KDIGLKFKNK EDASGLLAEK EKLTQQKKEL TEKEQQEDKD LKKKVFQVGN IVHPSVVVSN 120
  121 DEENNELVRT WKPEDLEAVG PIASVTGKPA SLSHHEILLR LDGYDPDRGV KICGHRGYFF 180
  181 RNYGVFLNQA LINYGLQFLA AKGYIPLQAP VMMNKELMSK TAQLSEFDEE LYKVIDGEDE 240
  241 KYLIATSEQP ISAYHSGEWF EKPQEQLPIH YVGYSSCFRR EAGSHGKDAW GVFRVHAFEK 300
  301 IEQFVITEPE KSWEEFEKMI SYSEEFYKSL KLPYRIVGIV SGELNNAAAK KYDLEAWFPY 360
  361 QKEYKELVSC SNCTDYQSRN LEIRCGIKKM GDREKKYVHC LNSTLAATQR ALCCILENYQ 420
  421 TEDGLVVPEV LRKYIPGEPE FLPFVNELPK NSTSSKDKKK KN

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		DRE2 SES1 TAH18
View Details	Gavin AC, et al. (2002)		AEP1 AEP2 ATP22 HRP1 SES1 TSR1
View Details	Ho Y, et al. (2002)		AAT2 ABP1 ACH1 ACO1 ADH2 ADH6 ADK1 AFR1 AHP1 AIM41 AIR2 ARC1 ARF1 ARG1 ATP3 ATP4 AVO1 BEM2 BUD14 CAR2 CDC33 CLU1 COF1 COP1 COR1 CPR1 CRZ1 CYR1 CYS4 DCP1 DCP2 DED1 DNM1 DUF1 EDC3 EDE1 EGD1 EGD2 ENP1 ERG13 ERG6 FET4 FOL2 FPR1 FRS2 GAS1 GCN3 GND1 GND2 GPH1 GRX1 GUS1 HEF3 HHF1, HHF2 HRR25 HSP104 HTB2 HXT6 HXT7 HYP2 ILV5 IPP1 KGD2 KRS1 LHS1 LOC1 LPD1 LRO1 LSP1 LTV1 MDH1 MDS3 MET6 MGE1 MRPS35 NIP1 NPL3 NSA1 NTF2 NUG1 OLA1 OYE2 PDC6 PEX19 PFK1 PIL1 PIN4 PMI40 POR1 PRM2 PTC4 PUF3 QCR2 RIO2 RNR2 RPC19 RPG1 RPM2 RSN1 RVB2 RVS161 RVS167 SAH1 SAP185 SAP190 SAS10 SCP160 SEC2 SEC23 SEC53 SEN15 SES1 SFB3 SGM1 SIR1 SIR3 SIT4 SNU13 SOD1 SRP1 SRV2 TEF4 THS1 TIF1, TIF2 TIF34 TIF35 TMA19 TMA29 TRP5 TSA2 TSR1 UBA1 UBI4 VMA4 VMA5 WTM1 YBL036C YBR225W YER138C YNK1

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	DAD1	Dam1-765 complex purified from yeast with Dad1-TAP	Shimogawa MM, et al. (2006)
View Run	MLP2	#25 Asynchronous Prep3-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)
View Run	MLP2	#08 Alpha Factor Prep4-TiO2 Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	SES1	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..462]	PSI-BLAST	556.502279	Seryl-tRNA synthetase (SerRS)

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: SES1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: