Protein Overview: HAT1

General Information:
Name(s) found:	HAT1 / YPL001W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|965092\|gb\|AAB68104.1\| Hat1p [NCBI NR] gi\|683789\|emb\|CAA88385.1\| unknown [Saccharomyces cerevisiae] [NCBI NR] gi\|6325256\|ref\|NP_015324.1\| Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break [NCBI NR] gi\|2498433\|sp\|Q12341.1\|HAT1_YEAST RecName: Full=Histone acetyltransferase type B catalytic subunit [NCBI NR] pir\|\|A57583 histone acetyltransferase (EC 2.3.1.48) HAT1 - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1585634\|prf\|\|2201411A histone H4 acetyltransferase [NCBI NR] gi\|1314075\|emb\|CAA95040.1\| unknown [Saccharomyces cerevisiae] [NCBI NR] Histone acetyltransferase type B catalytic subunit OS=Saccharomyces cerevisiae GN=HAT1 PE=1 SV=1 [Swiss-Prot] HAT1 Histone acetyltransferase subunit [mips] Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair [SGD] (Q12341) Histone acetyltransferase type B catalytic subunit (EC 2.3.1.48) [4932.FASTACCERV.txt] Chr XVI from 554600-555724 [hmr_yeast5_DM3-1_pombe.fasta] HAT1, Chr XVI from 554600-555724 [yeast_orfs2] HAT1 SGDID:S0005922, Chr XVI from 554600-555724, Verified ORF [yeastflysequest.fasta] HAT1 SGDID:S0005922, Chr XVI from 554602-555726, Verified ORF [10112005cervSGD.fasta] Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair [Saccharomyces cerevi [nrdb_11152004_Chlamydomonas] HAT1 SGDID:S000005922, Chr XVI from 554602-555726, Verified ORF, "Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta] histone H4 acetyltransferase [nr-271106-contam.fasta] Histone acetyltransferase type B catalytic subunit [nr-271106-contam.fasta] Hat1p [nr-271106-contam.fasta] Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair; Hat1p [Saccharomyces [nr-271106-contam.fasta] HAT1 SGDID:S000005922, Chr XVI from 554602-555726, Verified ORF, "Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Histone acetyltransferase type B catalytic subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HAT1 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] HAT1 SGDID:S000005922, Chr XVI from 554605-555729, Genome Release 64-1-1, Verified ORF, "Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair" [yeast-030211-contam.fasta] HAT1 SGDID:S000005922, Chr XVI from 554605-555729, Genome Release 64-2-1, Verified ORF, "Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex; uses the cofactor acetyl coenzyme A to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair" [20141208_orf_trans.fasta] YPL001W SGDID:S000005922, Chr XVI from 554605-555729, Genome Release 64-1-1, Verified ORF, "Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	374 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA ] cytoplasm [IDA ] histone acetyltransferase complex [IDA ][IPI ]
Biological Process:	histone acetylation [IDA ][IMP ] chromatin silencing at telomere [IGI ]
Molecular Function:	histone binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSANDFKPET WTSSANEALR VSIVGENAVQ FSPLFTYPIY GDSEKIYGYK DLIIHLAFDS  60
   61 VTFKPYVNVK YSAKLGDDNI VDVEKKLLSF LPKDDVIVRD EAKWVDCFAE ERKTHNLSDV 120
  121 FEKVSEYSLN GEEFVVYKSS LVDDFARRMH RRVQIFSLLF IEAANYIDET DPSWQIYWLL 180
  181 NKKTKELIGF VTTYKYWHYL GAKSFDEDID KKFRAKISQF LIFPPYQNKG HGSCLYEAII 240
  241 QSWLEDKSIT EITVEDPNEA FDDLRDRNDI QRLRKLGYDA VFQKHSDLSD EFLESSRKSL 300
  301 KLEERQFNRL VEMLLLLNNS PSFELKVKNR LYIKNYDALD QTDPEKAREA LQNSFILVKD 360
  361 DYRRIIESIN KSQG

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		ASF1 HAT1 HAT2 HHF1, HHF2 HHT1, HHT2 HIF1 MAM33 ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 POB3 PSE1 PSH1 PTC4 RTT106 SPT16
View Details	(MIPS) Mewes HW, et al. (2004)		HAT1 HAT2
View Details	Krogan NJ, et al. (2006)		HAT1 HAT2 ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 SWE1 YJR154W
View Details	Gavin AC, et al. (2006)		HAT1 HAT2 HHF1, HHF2 HIF1
View Details	Gavin AC, et al. (2002)		BDF2 CDC45 CDC55 CKB1 DYN1 ECM5 ERG26 GLT1 GLY1 HAT1 HAT2 HHF1, HHF2 HIF1 HSM3 HSP42 ICL1 IML1 KAP123 KRE33 LIP2 LYS12 MAC1 MCM2 MCM5 MCM6 MCM7 MDN1 MIS1 MSB1 NIP1 NMD5 ORC1 ORC2 ORC3 ORC4 ORC5 ORC6 PFK1 PRO1 PRT1 PSD2 PSE1 PSH1 RPA135 RPC40 RPD3 RPG1 RPN12 RPN3 RPN6 RPN8 RPN9 RPT2 RPT3 RPT5 RPT6 RSC3 SAM1 SIN3 TEL1 TFP1 TSC11 USO1 UTP20 VTH2 YFR006W YPR077C
View Details	Ho Y, et al. (2002)		ELA1 GND1 HAT1 HAT2 HIF1 RTN1
View Details	Qiu et al. (2008)		HAT1 SAS3 YNG1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	HAT1	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..112]	PSI-BLAST	1865.0	Histone acetyltransferase HAT1
2	View Details	[113..268]	PSI-BLAST	1865.0	Histone acetyltransferase HAT1
3	View Details	[269..374]	PSI-BLAST	1865.0	Histone acetyltransferase HAT1

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: HAT1

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: