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Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. A multisubunit complex that catalyzes the acetylation of histone H3. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. A protein complex that possesses histone acetyltransferase activity. A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. A multisubunit complex that catalyzes the acetylation of histones H4 and H2A. That part of the nuclear content other than the chromosomes or the nucleolus. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus. A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the expression of a subset of Pol II-transcribed genes. The budding yeast complex includes the acetyltransferase Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: histone acetyltransferase complex
Acc: GO:0000123
Aspect: Cellular Component
Desc: A protein complex that possesses histone acetyltransferase activity.
Synonyms:
  • histone acetylase complex
Proteins in PDR annotated with:
   This term: 61 [Search]
   Term or descendants: 220 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0000123 - histone acetyltransferase complex (interactive image map)
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