YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: TCB1

General Information:
Name(s) found: TCB1 / YOR086C [SGD]
Description(s) found:
Found 30 descriptions.
SHOW ALL
  • Lipid-binding protein containing three calcium and lipid binding domains; non-tagged protein localizes to mitochondria and GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1186 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: lipid binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKEDTGVTA PKKPETAQVA NINGIDKLEP PKTKEETESS KSVSSEKAAH ASDESFKRSI  60
   61 HEASYVGWKQ IGGWEDKDEL TLDDELMDMT RETFLDNIIP DSLYGDWYHS VAIFFIGGVA 120
  121 SFALGHYKFS MGSAFFVIVI TSLLYRTSAK KYRGSIRELV QKEFTVQKVE NDYESLEWLN 180
  181 AFLDKYWPIL EPSVSQLIVQ QANEQMATNE AIPKFITQLW IDELTLGVKP PRVDLVKTFQ 240
  241 NTASDVVVMD WGISFTPHDL CDMSAKQVRN YVNELAVVKA KIFGITIPVS VSDIAFKAHA 300
  301 RVKFKLMTPF PHVETVNIQL LKVPDFDFVA TLFGRSIFNW EILAIPGLMT LIQKMAKKYM 360
  361 GPILLPPFSL QLNIPQLLSG SNLSIGILEI TVKNAKGLKR TSSILNESID PYLSFEFNDI 420
  421 SIAKTRTVRD TLNPVWDETL YVLLNSFTDP LTISVYDKRA KLKDKVLGRI QYNLNTLHDK 480
  481 TTQRNLKAQF LRNSKPVGEL TFDLRFFPTL EEKKLPDGSV EELPDLNTGI AKVVVEEGSR 540
  541 FAEEEQKVTA YVEVYLNAKL VLTTGKATDT GTLKWNSDYE AVIADRRKTR YKFVVKDGKG 600
  601 EEIGSTIQTL NDLIDRSQVN KNLIPLKNQK GDIKITTYWR PVRLEIGSNS VAYTPPIGAI 660
  661 RVFIEKANDL RNLEKFGTID PYCKVLVNGL SKGRTDFKSQ TLNPVWNQVI YVAVTSPNQR 720
  721 ITLQCMDVET VNKDRSLGEF NVNVQDLFKK DENDKYEETI DEKAKVGRLV MPKKKPKGTI 780
  781 TYYTSFYPAL PVLTLEEIQD LDKVNKKKKA LELRKSAIDE KKISKEDKAK FDQEWNEVKE 840
  841 LEDMYSNRQK LDLPELLQYN QGVLAVTVLN GELPDSGLYV QAFFDDNGHP RFVSPRIPSR 900
  901 IVKNGWSGDV IIKELDKSIT TFRVAKNKNY NRVEKCVCEV ELPTQELVKN CYYKPSILHL 960
  961 SGEGSAKLML QISWFPIDTK QLPANDLITN SGDLTIMSRS AENLIASDLN GYSDPYLKYY1020
 1021 INNEEDCAYK TKVVKKTLNP KWNDEGTIQI NNRLNDVLRI KVMDWDSTSA DDTIGTAEIP1080
 1081 LNKVKVEGTT ELDVPVEGLE NAGQDGGMLH LAFSFKPRYT ISVSKREKKV GDIASKGLGT1140
 1141 GLKAGTTVIG GGVGAIGKIK KGVFGGLGSL TNHKKNHEMG EEETKF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) HFM1 LYS4 NEW1 RBG1 SGD1 SOK1 SSZ1 TCB1 TGL5 TMA46 YEF3 YLR072W ZUO1
    View Details Gavin AC, et al. (2002) ACC1 CCT8 CLU1 CPA2 FDH1 GCN20 GFA1 GUS1 ILV1 KAP123 LYS12 MRPL3 PSA1 RPA135 RPB2 RPN10 RPN11 RPN12 RPN8 RPT3 RPT5 RPT6 SAM1 SEC27 SMC3 TCB1 TIF1, TIF2 TSA1 TUB3 URA7 VAS1 YOL098C
    View Details Ho Y, et al. (2002) AAC1 AAC3 ADE5,7 AHA1 ARC1 ARO1 ARP2 ATG11 ATG12 ATG17 CAR2 COP1 CPA2 CPR6 ECM29 FET4 GCD11 GFA1 GUS1 IPP1 PAA1 PPX1 PRB1 PTC3 PTC7 REP1 REX2 RPN10 RPN11 RPN3 RPN5 RPN6 RPN7 RPT1 RPT3 SEC18 TCB1 TDA10 TIF1, TIF2 TYR1 YHR020W YHR033W YNL208W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RLF2 cac1: TAP-tagged Green EM, et al (2005)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #04 Alpha Factor Prep2 Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CDC48 TCB1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data TCB1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..80] deduced N/A Confident ab initio structure predictions are available.
    2 View Details [81..370] MSA 1.083986 View MSA. No confident structure predictions are available.
    3 View Details [371..506] PSI-BLAST 8.0 Domain from protein kinase C epsilon
    4 View Details [507..640] PSI-BLAST 118.373389 Synaptogamin I
    5 View Details [641..791] PSI-BLAST 118.373389 Synaptogamin I
    6 View Details [792..930] deduced N/A No confident structure predictions are available.
    7 View Details [931..1130] PSI-BLAST 117.325697 C2 domain from protein kinase c (alpha)
    8 View Details [1131..1186] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle