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Protein Overview: RIX7

General Information:
Name(s) found: RIX7 / YLL034C [SGD]
Description(s) found:
Found 23 descriptions.
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  • Putative ATPase of the AAA family, required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 837 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    nucleolus [IDALink to PubMed articleLink to PubMed article]
    Biological Process: ribosomal large subunit export from nucleus [IMPLink to PubMed article]
    Molecular Function: ATPase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKVKSKKNS LTSSLDNKIV DLIYRLLEEK TLDRKRSLRQ ESQGEEGENN EGEEDEDIFE  60
   61 SMFFAKDLTA GEIFTFCLTK DLSLQRVKKV VLQKTIDRML KDVIESELEE FGSYPGYNNE 120
  121 EEEKPSLEEE LAKKNMMIER DTNEMNKRIT STWSKSGSVS ESITETDDPK TEEVKKSKKR 180
  181 SKEGTCKVKR QKIKEDRSPP NSSLKSLGGM DDVVAQLMEL IGLPILHPEI FLSTGVEPPR 240
  241 GVLLHGPPGC GKTSIANALA GELQVPFISI SAPSVVSGMS GESEKKIRDL FDEARSLAPC 300
  301 LVFFDEIDAI TPKRDGGAQR EMERRIVAQL LTSMDELTME KTNGKPVIII GATNRPDSLD 360
  361 AALRRAGRFD REICLNVPNE VSRLHILKKM SDNLKIDGAI DFAKLAKLTP GFVGADLKAL 420
  421 VTAAGTCAIK RIFQTYANIK STPTTATDSS EDNMEIDETA NGDESSLKNT ANMIDPLPLS 480
  481 VVQQFIRNYP EPLSGEQLSL LSIKYEDFLK ALPTIQPTAK REGFATVPDV TWANVGALQR 540
  541 VRLELNMAIV QPIKRPELYE KVGISAPGGV LLWGPPGCGK TLLAKAVANE SRANFISIKG 600
  601 PELLNKYVGE SERSIRQVFT RARASVPCVI FFDELDALVP RRDTSLSESS SRVVNTLLTE 660
  661 LDGLNDRRGI FVIGATNRPD MIDPAMLRPG RLDKSLFIEL PNTEEKLDII KTLTKSHGTP 720
  721 LSSDVDFEEI IRNEKCNNFS GADLAALVRE SSVLALKRKF FQSEEIQSVL DNDLDKEFED 780
  781 LSVGVSGEEI IVTMSDFRSA LRKIKPSVSD KDRLKYDRLN KKMGLTEEMK DAEEMKQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARX1 BRX1 CIC1 DBP10 DRS1 ERB1 HAS1 MAK21 NIP7 NOC2 NOC3 NOG1 NOP15 NOP2 NOP4 NOP7 NSA1 NUG1 PUF6 RIX1 RIX7 RLP7 RPF1 RRP1 SPB1 SPB4 YTM1
    View Details Hazbun TR, et al. (2003) AMN1 AXL2 IMH1 PEX19 PFK27 RAX2 RGT2 RIC1 RIX7 RPA190 SST2 TRX1 TRX2 YLR035C-A
    View Details Gavin AC, et al. (2006) FPR4 NOP13 PUF6 RIX7 RPL20A
    View Details Gavin AC, et al. (2002) ARX1 BEM2 BMS1 BRX1 BUD20 CIC1 CLU1 CYR1 CYS4 DBP10 DBP9 DCP2 DRS1 EBP2 ERB1 FPR4 GCN1 HAS1 HDA1 HER1 HIS3 INP2 IPI1 IPI3 KRE33 LHP1 LOC1 LSG1 MAK21 MAK5 MDN1 MIS1 MRT4 NAP1 NIP1 NIP7 NMD3 NOC2 NOC3 NOG1 NOG2 NOP1 NOP12 NOP15 NOP16 NOP2 NOP4 NOP56 NOP7 NSA1 NSA2 NUG1 PRT1 PUF6 REI1 RIX1 RIX7 RLP24 RLP7 RPA135 RPA190 RPF1 RPF2 RPG1 RPP2B RPT6 RRP1 RRP12 RSA3 RSA4 RTR1 SDA1 SEC7 SKI2 SNU13 SPB1 SPB4 SSF1 TIF6 TUB3 URB1 UTP10 UTP20 UTP22 YGL036W YTM1
    View Details Ho Y, et al. (2002) CDC53 GUF1 HRT1 IDH1 RIX7 RPN8 RTT101 SEC27
    View Details Qiu et al. (2008) DRS1 NOG2 RIX7

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RIX7 No Comments Hazbun TR, et al. (2003)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen APC9 RIX7 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RIX7 Hazbun TR, et al. (2003)
    View Data RIX7 Huh WK, et al. (2003)
    View Data RIX7 and NOP56 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105] PSI-BLAST 630.9897 Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
    2 View Details [106..201] PSI-BLAST 630.9897 Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
    3 View Details [202..377] PSI-BLAST 630.9897 Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
    4 View Details [378..474] PSI-BLAST 630.9897 Membrane fusion atpase p97 N-terminal domain , P97-Nn; Membrane fusion atpase p97, D1 domain; Membrane fusion atpase p97 domain 2, P97-Nc
    5 View Details [475..564] deduced N/A No confident structure predictions are available.
    6 View Details [565..782] Pfam 85.886057 ATPase family associated with various cellular activities (AAA) No confident structure predictions are available.
    7 View Details [783..837] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle