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Protein Overview: RAX2

General Information:
Name(s) found: RAX2 / YLR084C [SGD]
Description(s) found:
Found 25 descriptions.
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  • N-glycosylated protein involved in the maintenance of bud site selection during bipolar budding; localization requires Rax1p; RAX2 mRNA stability is regulated by Mpt5p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1220 amino acids

    Gene Ontology:
    Cellular Component: cellular bud neck [IDALink to PubMed articleLink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    membrane [ISSLink to PubMed article]
    cellular bud scar [IDALink to PubMed article]
    Biological Process: cellular bud site selection [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFVHRLWTLA FPFLVEISKA SQLENIKSLL DIEDNVLPNL NISQNNSNAV QILGGVDALS  60
   61 FYEYTGQQNF TKEIGPETSS HGLVYYSNNT YIQLEDASDD TRIDKITPFG VDSFILSGSG 120
  121 TINNISVGNQ ILYNLSTLSM TPIFNQSLGA VQAVLADNSS IYFGGNFSYN NGSMTGYSAL 180
  181 IWDSISNTTQ LLPFGGFGEN SSVNSIVKLN NDNILFAGQF YTLDDPSALI SSSNNGTNST 240
  241 SSLNATTLEL GQRIPLRYAS WDSQGSTTFA SDSLVCPNTN EDAWLYPDTS GSLVCNLPYE 300
  301 VSPTKIRLYN SQRSDSEISV FQILTDPSSS IMNLTYLDPL SGELKNCGEF CPLYSRATLL 360
  361 SASQNVSSSM DMITFIDNNK TDVKWTSDFQ DFAFVNELPV SSLKFVALNS YGGSVGLSGL 420
  421 ELYQDTFSTY ANDSLNEYGC SALTNDSSSS TLSSNDWYNG LTGESYIAAK YVPDQNEPIP 480
  481 RVKFYPNIIH PGHYTINMYT PGCLQDNTCS ARGIVNVTMW NQQNNTIMKT YLIYQNNDNL 540
  541 KYDQIYSGYL DFSPEIVLEY VSGIYTTNTA TVVVADQVNV ITVSLDAFNT LSDSSNAKKE 600
  601 TLLNGILQYQ KSNFTSTRLN ETKVGNTTLN LFPVKNYPKN SSLYADIYDN KLVIGGVSNR 660
  661 ISIVDLNDDF EVTSSKNQTI QGDVHGITKT NQGLLIFGDI LSSNNQSAVF LFNGSFENVF 720
  721 NQSRTVNSAL NISLANNDFI VLDNDYVVNA SSNALIRNSS SFSLSLWAAG NNGDGDVLFS 780
  781 GAVSHMQYGN LNGSVRFLNE NEIEPLNLEG GIVPYLGAYL NESATAYAYE VDSLNKIYFS 840
  841 NEVYPSWNWS SGITQMLYAD NQTLLAVSAG SSTTAELSIF DLRNLTMIAN ETLGSNARIN 900
  901 ALVNFEKNCS MLVGGDFQMT EPNCTGLCLY NYESKTWSTF LNNTIFGEIT QLSFTNSSEL 960
  961 IISGLFETKE YQSIRLGSFN LTNSTMIPLL SGSEGKLNSF TVTEDSIVAW NDTSLFIYRN1020
 1021 QEWNITSLPG NASSISSVSA IYTDIESNTL NKRGINNVNN GSILLLNGNF NISQYGYLQS1080
 1081 LLFDFQKWTP YFISETTNTS NYNPIIFINR DVSTEFNSQS PLANVNITVT SPQSTSSQPP1140
 1141 SSSASSESKS KSKKKKIGRG FVVLIGLALA LGTVSVLGIA GVILAYVFKD PEGDYKPIKP1200
 1201 RIDENEMLDT VPPEKLMKFV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Hazbun TR, et al. (2003) AMN1 AXL2 IMH1 PEX19 PFK27 RAX2 RGT2 RIC1 RIX7 RPA190 SST2 TRX1 TRX2 YLR035C-A
    View Details Krogan NJ, et al. (2006) CYS3 IPL1 RAX2 SER1 UBA1 YDR415C YER156C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RIX7 No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RAX2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1220] deduced N/A No confident structure predictions are available.
    2 View Details [597..772] deduced N/A No confident structure predictions are available.
    3 View Details [773..846] deduced N/A No confident structure predictions are available.
    4 View Details [847..1054] deduced N/A No confident structure predictions are available.
    5 View Details [1055..1138] deduced N/A No confident structure predictions are available.
    6 View Details [1139..1220] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.16129867759095 bayes_pls_golite062009
  • protein binding
    		•  1.40069187357924 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.37810819223456 bayes_pls_golite062009
  • GTPase regulator activity
    		•  1.30109857016182 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.28664652111481 bayes_pls_golite062009
  • enzyme regulator activity
    		•  0.957155201002138 bayes_pls_golite062009
  • cation channel activity
    		•  0.852133790882907 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  0.820543200551171 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  0.820543200551171 bayes_pls_golite062009
  • ion channel activity
    		•  0.758864161786375 bayes_pls_golite062009
  • gated channel activity
    		•  0.746871434679286 bayes_pls_golite062009
  • signal transducer activity
    		•  0.689775744703145 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.689775744703145 bayes_pls_golite062009
  • GDP-dissociation inhibitor activity
    		•  0.128923535412438 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.0852462445742306 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle