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Protein Overview: YCF1

General Information:
Name(s) found: YCF1 / YDR135C [SGD]
Description(s) found:
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  • gi|6920083|sp|P39109.2|YCFI_YEAST RecName: Full=Metal resistance protein YCF1; AltName: Full=Yeast cadmium factor 1 [NCBI NR]
  • gi|665668|emb|CAA88217.1| unknown [Saccharomyces cerevisiae] [NCBI NR]
  • gi|6320339|ref|NP_010419.1| Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis [NCBI NR]
  • pir||S51863 cadmium resistance protein YCF1 - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • Metal resistance protein YCF1 OS=Saccharomyces cerevisiae GN=YCF1 PE=1 SV=2 [Swiss-Prot]
  • YCF1 Vacuolar `full-size` ABC transporter responsible for vacuolar sequestration of glutathione-S-conjugates [mips]
  • Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR [SGD]
  • YCF1, Chr IV from 722997-727544, reverse complement [yeast_orfs2]
  • Chr IV from 722997-727544, reverse complement [yeastorf3.fasta]
  • Chr IV from 727544-722997, reverse complement [yeastorf5.fasta]
  • (P39109) Metal resistance protein YCF1 (Yeast cadmium factor 1) [4932.FASTACCERV.txt]
  • YCF1 SGDID:S0002542, Chr IV from 727545-722998, reverse complement, Verified ORF [yeastflysequest.fasta]
  • YCF1 SGDID:S0002542, Chr IV from 727546-722999, reverse complement, Verified ORF [10112005cervSGD.fasta]
  • Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR [Saccharomyces [nrdb_11152004_Chlamydomonas]
  • YCF1 SGDID:S000002542, Chr IV from 727546-722999, reverse complement, Verified ORF, "Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YCF1 SGDID:S000002542, Chr IV from 727548-723001, reverse complement, Verified ORF, "Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports [yeast-contam.fasta]
  • YCF1 SGDID:S000002542, Chr IV from 727549-723002, reverse complement, Verified ORF, "Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR; Ycf1p [Sacchar [nr-271106-contam.fasta]
  • unknown [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • Metal resistance protein YCF1 (Yeast cadmium factor 1) [nr-271106-contam.fasta]
  • YCF1 SGDID:S000002542, Chr IV from 727549-723002, reverse complement, Verified ORF, "Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR" [yeast-bovrabprots.fasta]
  • YCF1 SGDID:S000002542, Chr IV from 727548-723001, reverse complement, Verified ORF, "Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR" [yeast-contam_custom.fasta]
  • [chemostatdb.fasta]
  • Metal resistance protein YCF1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YCF1 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • YCF1 SGDID:S000002542, Chr IV from 727551-723004, Genome Release 64-1-1, reverse complement, Verified ORF, "Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR" [yeast-030211-contam.fasta]
  • YCF1 SGDID:S000002542, Chr IV from 727551-723004, Genome Release 64-2-1, reverse complement, Verified ORF, "Vacuolar glutathione S-conjugate transporter; ABC-C transporter of the ATP-binding cassette family; required for vacuole fusion; forms stable complexes with vacuole fusion machinery; regulates Vam7p recruitment to vacuoles; role in detoxifying metals (Cd, Hg, As); transports GSSG that is not immediately reduced in cytosol to vacuole; transports unconjugated bilirubin, selenodigluthatione, oxidized glutathione; similar to human cystic fibrosis protein CFTR" [20141208_orf_trans.fasta]
  • YDR135C SGDID:S000002542, Chr IV from 727551-723004, Genome Release 64-1-1, reverse complement, Verified ORF, "Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 1515 amino acids

    Gene Ontology:
    Cellular Component: vacuolar membrane [IDALink to PubMed article]
    Biological Process: response to drug [IMPLink to PubMed article]
    response to metal ion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article][TASLink to PubMed article]
    bilirubin transport [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: glutathione S-conjugate-exporting ATPase activity [IDALink to PubMed articleLink to PubMed articleLink to PubMed articleLink to PubMed article]
    bilirubin transmembrane transporter activity [IGILink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGNLVSWAC KLCRSPEGFG PISFYGDFTQ CFIDGVILNL SAIFMITFGI RDLVNLCKKK  60
   61 HSGIKYRRNW IIVSRMALVL LEIAFVSLAS LNISKEEAEN FTIVSQYAST MLSLFVALAL 120
  121 HWIEYDRSVV ANTVLLFYWL FETFGNFAKL INILIRHTYE GIWYSGQTGF ILTLFQVITC 180
  181 ASILLLEALP KKPLMPHQHI HQTLTRRKPN PYDSANIFSR ITFSWMSGLM KTGYEKYLVE 240
  241 ADLYKLPRNF SSEELSQKLE KNWENELKQK SNPSLSWAIC RTFGSKMLLA AFFKAIHDVL 300
  301 AFTQPQLLRI LIKFVTDYNS ERQDDHSSLQ GFENNHPQKL PIVRGFLIAF AMFLVGFTQT 360
  361 SVLHQYFLNV FNTGMYIKSA LTALIYQKSL VLSNEASGLS STGDIVNLMS VDVQKLQDLT 420
  421 QWLNLIWSGP FQIIICLYSL YKLLGNSMWV GVIILVIMMP LNSFLMRIQK KLQKSQMKYK 480
  481 DERTRVISEI LNNIKSLKLY AWEKPYREKL EEVRNNKELK NLTKLGCYMA VTSFQFNIVP 540
  541 FLVSCCTFAV FVYTEDRALT TDLVFPALTL FNLLSFPLMI IPMVLNSFIE ASVSIGRLFT 600
  601 FFTNEELQPD SVQRLPKVKN IGDVAINIGD DATFLWQRKP EYKVALKNIN FQAKKGNLTC 660
  661 IVGKVGSGKT ALLSCMLGDL FRVKGFATVH GSVAYVSQVP WIMNGTVKEN ILFGHRYDAE 720
  721 FYEKTIKACA LTIDLAILMD GDKTLVGEKG ISLSGGQKAR LSLARAVYAR ADTYLLDDPL 780
  781 AAVDEHVARH LIEHVLGPNG LLHTKTKVLA TNKVSALSIA DSIALLDNGE ITQQGTYDEI 840
  841 TKDADSPLWK LLNNYGKKNN GKSNEFGDSS ESSVRESSIP VEGELEQLQK LNDLDFGNSD 900
  901 AISLRRASDA TLGSIDFGDD ENIAKREHRE QGKVKWNIYL EYAKACNPKS VCVFILFIVI 960
  961 SMFLSVMGNV WLKHWSEVNS RYGSNPNAAR YLAIYFALGI GSALATLIQT IVLWVFCTIH1020
 1021 ASKYLHNLMT NSVLRAPMTF FETTPIGRIL NRFSNDIYKV DALLGRTFSQ FFVNAVKVTF1080
 1081 TITVICATTW QFIFIIIPLS VFYIYYQQYY LRTSRELRRL DSITRSPIYS HFQETLGGLA1140
 1141 TVRGYSQQKR FSHINQCRID NNMSAFYPSI NANRWLAYRL ELIGSIIILG AATLSVFRLK1200
 1201 QGTLTAGMVG LSLSYALQIT QTLNWIVRMT VEVETNIVSV ERIKEYADLK SEAPLIVEGH1260
 1261 RPPKEWPSQG DIKFNNYSTR YRPELDLVLK HINIHIKPNE KVGIVGRTGA GKSSLTLALF1320
 1321 RMIEASEGNI VIDNIAINEI GLYDLRHKLS IIPQDSQVFE GTVRENIDPI NQYTDEAIWR1380
 1381 ALELSHLKEH VLSMSNDGLD AQLTEGGGNL SVGQRQLLCL ARAMLVPSKI LVLDEATAAV1440
 1441 DVETDKVVQE TIRTAFKDRT ILTIAHRLNT IMDSDRIIVL DNGKVAEFDS PGQLLSDNKS1500
 1501 LFYSLCMEAG LVNEN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) BPT1 GAP1 YBT1 YCF1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run VAM3 sample: hx1 Hao Xu, et al. (2010)
    View Run VAM3 sample: hx3 Hao Xu, et al. (2010)
    View Run VAM3 sample: hx4 Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX11 - both fusion and trans-SNARE complex formation take place. Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control). Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX13 - trans-SNARE complex forms but fusion is blocked. Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX14 - mixture in detergent (control). Hao Xu, et al. (2010)
    View Run VAM3 hx21: both fusion and trans-SNARE complex formation take place. Investigating Vam3p, Nyv1p and their partners in trans-SNARE complex Hao Xu, et al. (2010)
    View Run VAM3 hx23: mixture in detergent (control) Investigating Vam3p, Nyv1p and their partners in trans-SNARE complex Hao Xu, et al. (2010)
    View Run MLP2 #26 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps1-2 Keck JM, et al. (2011)
    View Run MLP2 #27 Asynchronous Prep4-TiO2 Phosphopeptide enriched, Steps3-5 Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YCF1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..267] MSA 1.227979 View MSA. No confident structure predictions are available.
    2 View Details [268..609] Pfam 56.79588 ABC transporter transmembrane region No confident structure predictions are available.
    3 View Details [610..865] PSI-BLAST 445.325697 No description for 1nbd__ was found.
    4 View Details [866..934] deduced N/A No confident structure predictions are available.
    5 View Details [935..1032]
    [1051..1248]    		 PSI-BLAST 525.218487 MsbA
    6 View Details [1033..1050]
    [1249..1515]    		 PSI-BLAST 525.218487 MsbA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • lipid transporter activity
    		•  7.47642599298853 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  6.80339337010085 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  5.57844095962502 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  5.57813579764186 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  5.57813579764186 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  5.5689620139321 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  5.55992639965745 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  5.50005167063544 bayes_pls_golite062009
  • cation channel activity
    		•  5.46287131955314 bayes_pls_golite062009
  • homoaconitate hydratase activity
    		•  5.33234586981482 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  5.29074477899638 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  5.1184221202951 bayes_pls_golite062009
  • potassium channel activity
    		•  5.11125652739479 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  5.10064970232011 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  4.98276715440477 bayes_pls_golite062009
  • ion channel activity
    		•  4.87468443062464 bayes_pls_golite062009
  • peptide antigen-transporting ATPase activity
    		•  4.81855985294388 bayes_pls_golite062009
  • channel activity
    		•  4.74517495695421 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  4.74517495695421 bayes_pls_golite062009
  • peptide transporter activity
    		•  4.7442815698413 bayes_pls_golite062009
  • anion transmembrane-transporting ATPase activity
    		•  4.71935767060308 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  4.71152823189573 bayes_pls_golite062009
  • ATPase activity
    		•  4.69795387297193 bayes_pls_golite062009
  • peptide-transporting ATPase activity
    		•  4.63590351019108 bayes_pls_golite062009
  • cadmium ion transmembrane transporter activity
    		•  4.62439240790153 bayes_pls_golite062009
  • gated channel activity
    		•  4.61941650351493 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  4.56509805974548 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  4.45975815173802 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  4.45923622153365 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  4.39781350157199 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  4.38133275795019 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  4.38085303582726 bayes_pls_golite062009
  • sulfonylurea receptor activity
    		•  4.29224907929661 bayes_pls_golite062009
  • bilirubin transmembrane transporter activity
    		•  4.16465937144981 bayes_pls_golite062009
  • hydrolase activity
    		•  4.12107348093071 bayes_pls_golite062009
  • oligopeptide-transporting ATPase activity
    		•  4.09365342567844 bayes_pls_golite062009
  • transporter activity
    		•  3.71239480053329 bayes_pls_golite062009
  • structural molecule activity
    		•  3.58406348799895 bayes_pls_golite062009
  • TAP binding
    		•  3.43940121529172 bayes_pls_golite062009
  • TAP1 binding
    		•  3.43940121529172 bayes_pls_golite062009
  • TAP2 binding
    		•  3.43940121529172 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.35436118751376 bayes_pls_golite062009
  • phosphate transmembrane-transporting ATPase activity
    		•  3.20894563245332 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  3.16975154423199 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.13960906549884 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.13913638619234 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.1318898376276 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.08390071341252 bayes_pls_golite062009
  • iron ion transmembrane transporter activity
    		•  3.05511942104215 bayes_pls_golite062009
  • ATP binding
    		•  3.01346604299372 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.00745742755195 bayes_pls_golite062009
  • drug transmembrane transporter activity
    		•  2.97119034312001 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  2.96271391116269 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  2.9271291809464 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  2.91131545957759 bayes_pls_golite062009
  • tapasin binding
    		•  2.81937502401698 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  2.77610331510393 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  2.77610331510393 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  2.70262534541085 bayes_pls_golite062009
  • ribonucleotide binding
    		•  2.70178191749524 bayes_pls_golite062009
  • amine-transporting ATPase activity
    		•  2.69529191205818 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.67957846350199 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  2.67815672695824 bayes_pls_golite062009
  • purine nucleotide binding
    		•  2.6583477492092 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  2.63419811368692 bayes_pls_golite062009
  • nucleotide binding
    		•  2.62374702628143 bayes_pls_golite062009
  • sterol transporter activity
    		•  2.48473697371886 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.40292717311506 bayes_pls_golite062009
  • canalicular bile acid transmembrane transporter activity
    		•  2.33958437214304 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  2.29486577878686 bayes_pls_golite062009
  • binding
    		•  2.27048396817643 bayes_pls_golite062009
    		• 2.20174656498665 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  2.15147988861177 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.11222585187695 bayes_pls_golite062009
  • oligopeptide transporter activity
    		•  2.05580564974083 bayes_pls_golite062009
  • voltage-gated calcium channel activity
    		•  1.96314034513078 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  1.82177108193332 bayes_pls_golite062009
  • DNA binding
    		•  1.7904783386531 bayes_pls_golite062009
  • organic anion transmembrane transporter activity
    		•  1.76999970080179 bayes_pls_golite062009
  • protein transporter activity
    		•  1.71214667007262 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.68903321260301 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  1.59627719545436 bayes_pls_golite062009
  • phosphonate transmembrane transporter activity
    		•  1.40269234722336 bayes_pls_golite062009
  • signal recognition particle binding
    		•  1.39788601145414 bayes_pls_golite062009
  • monocarboxylic acid transmembrane transporter activity
    		•  1.37836402136387 bayes_pls_golite062009
  • glutathione transmembrane transporter activity
    		•  1.35514937365621 bayes_pls_golite062009
  • sphingolipid transporter activity
    		•  1.35514937365621 bayes_pls_golite062009
  • motor activity
    		•  1.34881124154297 bayes_pls_golite062009
  • peptide antigen binding
    		•  1.31965692009502 bayes_pls_golite062009
  • molybdate ion transmembrane transporter activity
    		•  1.28313088935613 bayes_pls_golite062009
  • molybdate transmembrane-transporting ATPase activity
    		•  1.28313088935613 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.23799860254751 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • peptidase activity
    		•  1.12876670227791 bayes_pls_golite062009
  • sulfate transmembrane-transporting ATPase activity
    		•  1.1220946941463 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  1.10251779925246 bayes_pls_golite062009
  • dipeptide transporter activity
    		•  1.01130176523309 bayes_pls_golite062009
  • signal transducer activity
    		•  0.952448314982579 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.952448314982579 bayes_pls_golite062009
    		• 0.869999622006359 bayes_pls_golite062009
  • GTPase activity
    		•  0.83849854735032 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  0.798934081014025 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  0.767424210804186 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.76547843267689 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.765442336337003 bayes_pls_golite062009
  • phospholipid transporter activity
    		•  0.755445322666929 bayes_pls_golite062009
  • glutathione S-conjugate-exporting ATPase activity
    		•  0.719430645205088 bayes_pls_golite062009
  • bile acid transmembrane transporter activity
    		•  0.687612064139871 bayes_pls_golite062009
  • high voltage-gated calcium channel activity
    		•  0.64930610472341 bayes_pls_golite062009
  • cholesterol transporter activity
    		•  0.644421039250979 bayes_pls_golite062009
  • transcription factor activity
    		•  0.603758349693077 bayes_pls_golite062009
  • ribonucleoprotein binding
    		•  0.46620222872538 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.46552249844591 bayes_pls_golite062009
  • long-chain fatty acid transporter activity
    		•  0.445784480190949 bayes_pls_golite062009
  • branched-chain aliphatic amino acid transmembrane transporter activity
    		•  0.442220326523999 bayes_pls_golite062009
  • signal sequence binding
    		•  0.42240724331108 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  0.40217318916177 bayes_pls_golite062009
  • catalytic activity
    		•  0.368034275052766 bayes_pls_golite062009
  • translation regulator activity
    		•  0.29096092258568 bayes_pls_golite062009
  • receptor activity
    		•  0.277332279568238 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.274994961137851 bayes_pls_golite062009
  • fatty acid transporter activity
    		•  0.251070374183928 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.243026482777117 bayes_pls_golite062009
  • neutral amino acid transmembrane transporter activity
    		•  0.227570438294493 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  0.219473333671469 bayes_pls_golite062009
  • apolipoprotein receptor activity
    		•  0.201503131198139 bayes_pls_golite062009
  • syntaxin-13 binding
    		•  0.201503131198139 bayes_pls_golite062009
  • apolipoprotein A-I binding
    		•  0.201503131198139 bayes_pls_golite062009
  • apolipoprotein A-I receptor activity
    		•  0.201503131198139 bayes_pls_golite062009
  • amino acid-transporting ATPase activity
    		•  0.147644650870465 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  0.12351419478929 bayes_pls_golite062009
  • sulfate transmembrane transporter activity
    		•  0.104477131120205 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.10236059675512 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0869561319004262 bayes_pls_golite062009
  • helicase activity
    		•  0.0775311459068899 bayes_pls_golite062009
  • RNA binding
    		•  0.0693163519626152 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  0.0536898657672154 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.0272673919333979 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.0132158893513235 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    		•  0.00571427458217011 bayes_pls_golite062009
  • macromolecule transmembrane transporter activity
    		•  0.00571427458217011 bayes_pls_golite062009
    4
    Term Confidence Notes
  • lipid transporter activity
    		•  6.95325922226092 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  5.4467861893359 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  5.44654566127945 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  5.44654566127945 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  5.43909190876515 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  5.4304944906989 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  5.38112407181712 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  4.87869064889244 bayes_pls_golite062009
  • ATPase activity
    		•  4.60773943958528 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  4.38591214726007 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  4.32673473878039 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  4.31087891816858 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  4.31037981322306 bayes_pls_golite062009
  • hydrolase activity
    		•  4.09315408758191 bayes_pls_golite062009
  • transporter activity
    		•  3.47953169973151 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.96171085039592 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.94175800357966 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.90743799425416 bayes_pls_golite062009
  • ATP binding
    		•  2.83986218503994 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  2.79195527951815 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  2.74359323245512 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  2.55506944753783 bayes_pls_golite062009
  • ribonucleotide binding
    		•  2.55426312645972 bayes_pls_golite062009
  • purine nucleotide binding
    		•  2.51344800975739 bayes_pls_golite062009
  • nucleotide binding
    		•  2.48057252852174 bayes_pls_golite062009
  • binding
    		•  2.24416672769019 bayes_pls_golite062009
  • catalytic activity
    		•  0.372934161904337 bayes_pls_golite062009
    5
    Term Confidence Notes
  • metal ion transmembrane transporter activity
    		•  6.80339337010085 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  6.58863529263644 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  6.58067278719409 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  6.57974651657836 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  6.57922174989907 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  6.57807080367604 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  6.48406410175216 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  6.48154954364331 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  6.40467109535527 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  6.40151534181487 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  6.38373914253885 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  6.38247436082206 bayes_pls_golite062009
  • ATPase activity
    		•  6.30019941712404 bayes_pls_golite062009
  • hydrolase activity
    		•  5.58566368416351 bayes_pls_golite062009
  • cation channel activity
    		•  5.46287131955314 bayes_pls_golite062009
  • homoaconitate hydratase activity
    		•  5.33234586981482 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  5.29074477899638 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  5.1184221202951 bayes_pls_golite062009
  • potassium channel activity
    		•  5.11125652739479 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  5.10064970232011 bayes_pls_golite062009
  • ion channel activity
    		•  4.87468443062464 bayes_pls_golite062009
  • peptide antigen-transporting ATPase activity
    		•  4.81855985294388 bayes_pls_golite062009
  • channel activity
    		•  4.74517495695421 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  4.74517495695421 bayes_pls_golite062009
  • peptide transporter activity
    		•  4.7442815698413 bayes_pls_golite062009
  • anion transmembrane-transporting ATPase activity
    		•  4.71935767060308 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  4.71152823189573 bayes_pls_golite062009
  • peptide-transporting ATPase activity
    		•  4.63590351019108 bayes_pls_golite062009
  • cadmium ion transmembrane transporter activity
    		•  4.62439240790153 bayes_pls_golite062009
  • gated channel activity
    		•  4.61941650351493 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  4.56509805974548 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  4.45975815173802 bayes_pls_golite062009
  • sulfonylurea receptor activity
    		•  4.29224907929661 bayes_pls_golite062009
  • bilirubin transmembrane transporter activity
    		•  4.16465937144981 bayes_pls_golite062009
  • oligopeptide-transporting ATPase activity
    		•  4.09365342567844 bayes_pls_golite062009
  • structural molecule activity
    		•  3.58406348799895 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.4837867129694 bayes_pls_golite062009
  • TAP binding
    		•  3.43940121529172 bayes_pls_golite062009
  • TAP1 binding
    		•  3.43940121529172 bayes_pls_golite062009
  • TAP2 binding
    		•  3.43940121529172 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  3.40690615950081 bayes_pls_golite062009
  • ribonucleotide binding
    		•  3.40594996232845 bayes_pls_golite062009
  • purine nucleotide binding
    		•  3.3669118613715 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  3.35436118751376 bayes_pls_golite062009
  • nucleotide binding
    		•  3.33248266870364 bayes_pls_golite062009
  • phosphate transmembrane-transporting ATPase activity
    		•  3.20894563245332 bayes_pls_golite062009
  • ATP binding
    		•  3.17398570826788 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  3.16975154423199 bayes_pls_golite062009
  • lipid transporter activity
    		•  3.14635082108971 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.13913638619234 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  3.12628113185041 bayes_pls_golite062009
  • transporter activity
    		•  3.10463051760206 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.08390071341252 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  3.0710107594224 bayes_pls_golite062009
  • iron ion transmembrane transporter activity
    		•  3.05511942104215 bayes_pls_golite062009
  • drug transmembrane transporter activity
    		•  2.97119034312001 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.95886887664984 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  2.9271291809464 bayes_pls_golite062009
  • tapasin binding
    		•  2.81937502401698 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  2.77610331510393 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  2.77610331510393 bayes_pls_golite062009
  • amine-transporting ATPase activity
    		•  2.69529191205818 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.67957846350199 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  2.67815672695824 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  2.63419811368692 bayes_pls_golite062009
  • sterol transporter activity
    		•  2.48473697371886 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.40292717311506 bayes_pls_golite062009
  • canalicular bile acid transmembrane transporter activity
    		•  2.33958437214304 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  2.29486577878686 bayes_pls_golite062009
    		• 2.20174656498665 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  2.15147988861177 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.11222585187695 bayes_pls_golite062009
  • oligopeptide transporter activity
    		•  2.05580564974083 bayes_pls_golite062009
  • voltage-gated calcium channel activity
    		•  1.96314034513078 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.91091452720653 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  1.82177108193332 bayes_pls_golite062009
  • DNA binding
    		•  1.7904783386531 bayes_pls_golite062009
  • organic anion transmembrane transporter activity
    		•  1.76999970080179 bayes_pls_golite062009
  • protein transporter activity
    		•  1.71214667007262 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.68903321260301 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  1.59627719545436 bayes_pls_golite062009
  • phosphonate transmembrane transporter activity
    		•  1.40269234722336 bayes_pls_golite062009
  • signal recognition particle binding
    		•  1.39788601145414 bayes_pls_golite062009
  • monocarboxylic acid transmembrane transporter activity
    		•  1.37836402136387 bayes_pls_golite062009
  • glutathione transmembrane transporter activity
    		•  1.35514937365621 bayes_pls_golite062009
  • sphingolipid transporter activity
    		•  1.35514937365621 bayes_pls_golite062009
  • motor activity
    		•  1.34881124154297 bayes_pls_golite062009
  • peptide antigen binding
    		•  1.31965692009502 bayes_pls_golite062009
  • molybdate ion transmembrane transporter activity
    		•  1.28313088935613 bayes_pls_golite062009
  • molybdate transmembrane-transporting ATPase activity
    		•  1.28313088935613 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  1.23799860254751 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • peptidase activity
    		•  1.12876670227791 bayes_pls_golite062009
  • sulfate transmembrane-transporting ATPase activity
    		•  1.1220946941463 bayes_pls_golite062009
  • nucleotide kinase activity
    		•  1.10251779925246 bayes_pls_golite062009
  • dipeptide transporter activity
    		•  1.01130176523309 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • signal transducer activity
    		•  0.952448314982579 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.952448314982579 bayes_pls_golite062009
    		• 0.869999622006359 bayes_pls_golite062009
  • GTPase activity
    		•  0.83849854735032 bayes_pls_golite062009
  • copper ion transmembrane transporter activity
    		•  0.798934081014025 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  0.767424210804186 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.76547843267689 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.765442336337003 bayes_pls_golite062009
  • phospholipid transporter activity
    		•  0.755445322666929 bayes_pls_golite062009
  • glutathione S-conjugate-exporting ATPase activity
    		•  0.719430645205088 bayes_pls_golite062009
  • bile acid transmembrane transporter activity
    		•  0.687612064139871 bayes_pls_golite062009
  • high voltage-gated calcium channel activity
    		•  0.64930610472341 bayes_pls_golite062009
  • cholesterol transporter activity
    		•  0.644421039250979 bayes_pls_golite062009
  • transcription factor activity
    		•  0.603758349693077 bayes_pls_golite062009
  • ribonucleoprotein binding
    		•  0.46620222872538 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  0.46552249844591 bayes_pls_golite062009
  • long-chain fatty acid transporter activity
    		•  0.445784480190949 bayes_pls_golite062009
  • branched-chain aliphatic amino acid transmembrane transporter activity
    		•  0.442220326523999 bayes_pls_golite062009
  • signal sequence binding
    		•  0.42240724331108 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  0.40217318916177 bayes_pls_golite062009
  • translation regulator activity
    		•  0.29096092258568 bayes_pls_golite062009
  • receptor activity
    		•  0.277332279568238 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  0.274994961137851 bayes_pls_golite062009
  • fatty acid transporter activity
    		•  0.251070374183928 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.243026482777117 bayes_pls_golite062009
  • neutral amino acid transmembrane transporter activity
    		•  0.227570438294493 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  0.219473333671469 bayes_pls_golite062009
  • apolipoprotein receptor activity
    		•  0.201503131198139 bayes_pls_golite062009
  • syntaxin-13 binding
    		•  0.201503131198139 bayes_pls_golite062009
  • apolipoprotein A-I binding
    		•  0.201503131198139 bayes_pls_golite062009
  • apolipoprotein A-I receptor activity
    		•  0.201503131198139 bayes_pls_golite062009
  • amino acid-transporting ATPase activity
    		•  0.147644650870465 bayes_pls_golite062009
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  0.12351419478929 bayes_pls_golite062009
  • sulfate transmembrane transporter activity
    		•  0.104477131120205 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.10236059675512 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0869561319004262 bayes_pls_golite062009
  • helicase activity
    		•  0.0775311459068899 bayes_pls_golite062009
  • RNA binding
    		•  0.0693163519626152 bayes_pls_golite062009
  • cation-transporting ATPase activity
    		•  0.0536898657672154 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.0272673919333979 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.0132158893513235 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven protein transmembrane transporter activity
    		•  0.00571427458217011 bayes_pls_golite062009
  • macromolecule transmembrane transporter activity
    		•  0.00571427458217011 bayes_pls_golite062009
    6 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle