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Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments. Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate. Catalysis of the reaction: GTP + H2O = GDP + phosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: GTPase activity
Acc: GO:0003924
Aspect: Molecular Function
Desc: Catalysis of the reaction: GTP + H2O = GDP + phosphate.
Synonyms:
  • heterotrimeric G-protein GTPase activity
  • tubulin GTPase activity
  • dynamin GTPase activity
  • Ran small monomeric GTPase activity
  • protein-synthesizing GTPase activity, termination
  • RHEB small monomeric GTPase activity
  • protein-synthesizing GTPase activity, initiation
  • protein-synthesizing GTPase activity, elongation
  • heterotrimeric G-protein GTPase, alpha-subunit
  • Sar small monomeric GTPase activity
  • Ras small monomeric GTPase activity
  • heterotrimeric G-protein GTPase, gamma-subunit
  • ARF small monomeric GTPase activity
  • small monomeric GTPase activity
  • Rho small monomeric GTPase activity
  • protein-synthesizing GTPase activity
  • signal-recognition-particle GTPase activity
  • heterotrimeric G-protein GTPase, beta-subunit
  • hydrolase activity, acting on acid anhydrides, acting on GTP, involved in cellular and subcellular movement
  • Rab small monomeric GTPase activity
Proteins in PDR annotated with:
   This term: 1021 [Search]
   Term or descendants: 1021 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0003924 - GTPase activity (interactive image map)

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