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Catalysis of movement along a polymeric molecule such as a microfilament or microtubule, coupled to the hydrolysis of a nucleoside triphosphate. Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments. Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate. Catalysis of the reaction: CTP + H2O = CDP + phosphate. May or may not be coupled to another reaction. Catalysis of the reaction: dTTP + H2O = dTDP + phosphate. Catalysis of the reaction: NTP + H2O = NDP + phosphate to drive the unwinding of a DNA or RNA helix. Catalysis of the reaction: GTP + H2O = GDP + phosphate. Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. Catalysis of the reaction: thiamin triphosphate + H2O = thiamin diphosphate + phosphate. Catalysis of the reaction: ATP + H2O = ADP + phosphate. May or may not be coupled to another reaction.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: nucleoside-triphosphatase activity
Acc: GO:0017111
Aspect: Molecular Function
Desc: Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
Synonyms:
  • nucleoside triphosphatase activity
  • unspecific diphosphate phosphohydrolase activity
  • nucleoside-5-triphosphate phosphohydrolase activity
  • apyrase activity
  • NTPase activity
  • nucleoside 5-triphosphatase activity
  • nucleoside triphosphate hydrolase activity
  • nucleoside triphosphate phosphohydrolase activity
Proteins in PDR annotated with:
   This term: 887 [Search]
   Term or descendants: 6521 [Refine Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0017111 - nucleoside-triphosphatase activity (interactive image map)

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