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Catalysis of the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus. Catalysis of energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules. Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts. Enables the transfer of a substance from one side of a membrane to the other. Catalysis of the temporally-regulated formation of a transmembrane protein hole that directly or indirectly allows murein hydrolyases to access their cell wall substrate. Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated. Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive. Catalysis of energy-independent facilitated diffusion, mediated by passage of proteins through a transmembrane aqueous pore or channel. Catalysis of the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient. Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: channel activity
Acc: GO:0015267
Aspect: Molecular Function
Desc: Catalysis of energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
Synonyms:
  • channel/pore class transporter activity
  • GO:0015268
  • alpha-type channel activity
  • pore class transporter activity
  • nonselective channel activity
  • pore activity
  • channel-forming toxin activity
  • GO:0015249
Proteins in PDR annotated with:
   This term: 20 [Search]
   Term or descendants: 2072 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0015267 - channel activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle