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Protein Overview: DIS3

Protein Complex Data

Mass Spectrometry Data

The following runs contain data for this protein:

  BAIT COMMENTS PUBLICATION
View Run BOI1 Sample bob1 (2nd set) from october 2005 McCusker D, et al (2007)
View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
View Run MLP2 #30 Asynchronous Prep6-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

  BAIT PREY HITS PUBLICATION
View Screen PRP16 DIS3 2 Unpublished Fields Lab Data

Microscopy / Localization Data

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  PROTEIN(S) PUBLICATION
View Data DIS3 Huh WK, et al. (2003)
View Data DIS3 and NOP56 Huh WK, et al. (2003)

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..325] MSA 1.038904 View MSA. No confident structure predictions are available.
2 View Details [326..415] MSA 1.081995 View MSA. No confident structure predictions are available.
3 View Details [416..823] Pfam 168.39794 RNB-like protein No confident structure predictions are available.
4 View Details [824..1001] PSI-BLAST 14.39794 C-terminal domain of RNA polymerase II subunit RBP4 (RpoE); N-terminal, heterodimerisation domain of RBP4 (RpoE)

Functions predicted (by domain):

# Gene Ontology predictions
1 No functions predicted.
2 No functions predicted.
3
Term Confidence Notes
  • ribonuclease activity
  • 7.42330864261751 bayes_pls_golite062009
  • exoribonuclease activity
  • 6.76241588209982 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
  • 6.73428326869965 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
  • 5.13367897180134 bayes_pls_golite062009
  • 3'-5' exonuclease activity
  • 3.51306349336452 bayes_pls_golite062009
  • nucleic acid binding
  • 3.194200758646 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
  • 3.07263153665399 bayes_pls_golite062009
  • binding
  • 2.83465364476231 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
  • 2.73968547121328 bayes_pls_golite062009
  • DNA binding
  • 2.71213098011194 bayes_pls_golite062009
  • exonuclease activity
  • 2.66053639652924 bayes_pls_golite062009
  • RNA binding
  • 2.41160981373213 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
  • 2.04350689362549 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
  • 2.04350689362549 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
  • 2.04218282227834 bayes_pls_golite062009
  • structural constituent of ribosome
  • 2.02605441840546 bayes_pls_golite062009
  • structure-specific DNA binding
  • 1.81524862921454 bayes_pls_golite062009
  • structural molecule activity
  • 1.81283970647925 bayes_pls_golite062009
  • single-stranded DNA binding
  • 1.62996999055328 bayes_pls_golite062009
  • 1.5765009871268 bayes_pls_golite062009
  • exoribonuclease II activity
  • 1.18248519339188 bayes_pls_golite062009
  • telomeric DNA binding
  • 1.15591101342538 bayes_pls_golite062009
  • ligase activity
  • 1.06979791212194 bayes_pls_golite062009
  • transcription regulator activity
  • 0.996884322431837 bayes_pls_golite062009
  • hydrolase activity
  • 0.724860465280978 bayes_pls_golite062009
  • single-stranded telomeric DNA binding
  • 0.586976595520399 bayes_pls_golite062009
  • nuclease activity
  • 0.57381531077345 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
  • 0.504302440847948 bayes_pls_golite062009
  • mRNA binding
  • 0.4162128308402 bayes_pls_golite062009
  • sequence-specific DNA binding
  • 0.32084431704638 bayes_pls_golite062009
  • transcription factor activity
  • 0.298729064067577 bayes_pls_golite062009
  • translation regulator activity
  • 0.22908707234671 bayes_pls_golite062009
  • chromatin binding
  • 0.1876135725713 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
  • 0.179682348023561 bayes_pls_golite062009
  • protein binding
  • 0.152645195799531 bayes_pls_golite062009
  • translation initiation factor activity
  • 0.11625379846973 bayes_pls_golite062009
  • RNA polymerase activity
  • 0.0740938021136293 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
  • 0.0740938021136293 bayes_pls_golite062009
    4 No functions predicted.




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle