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Protein Overview: SEC13

General Information:
Name(s) found: SEC13 / YLR208W [SGD]
Description(s) found:
Found 32 descriptions.
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  • Component of both the Nup84 nuclear pore sub-complex and the Sec13p-Sec31p complex of the COPII vesicle coat, required for vesicle formation in ER to Golgi transport and nuclear pore complex organization [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 297 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    extrinsic to membrane [IDALink to PubMed article]
    COPII vesicle coat [IDALink to PubMed article][TASLink to PubMed article]
    nuclear pore [IGILink to PubMed article][IPILink to PubMed article][TASLink to PubMed article]
    Biological Process: ER to Golgi vesicle-mediated transport [IDALink to PubMed article][TASLink to PubMed article]
    membrane budding [IDALink to PubMed article][IMPLink to PubMed article]
    nuclear pore organization [ICLink to PubMed article][TASLink to PubMed article]
    ER-associated protein catabolic process [IMPLink to PubMed article]
    Molecular Function: structural molecule activity [IDALink to PubMed article][IGILink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVIANAHNE LIHDAVLDYY GKRLATCSSD KTIKIFEVEG ETHKLIDTLT GHEGPVWRVD  60
   61 WAHPKFGTIL ASCSYDGKVL IWKEENGRWS QIAVHAVHSA SVNSVQWAPH EYGPLLLVAS 120
  121 SDGKVSVVEF KENGTTSPII IDAHAIGVNS ASWAPATIEE DGEHNGTKES RKFVTGGADN 180
  181 LVKIWKYNSD AQTYVLESTL EGHSDWVRDV AWSPTVLLRS YLASVSQDRT CIIWTQDNEQ 240
  241 GPWKKTLLKE EKFPDVLWRA SWSLSGNVLA LSGGDNKVTL WKENLEGKWE PAGEVHQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ERO1 NUP120 NUP145 NUP84 NUP85 SEC13 SEC16 SEC23 SEC31 SEH1
    View Details (MIPS) Mewes HW, et al. (2004) EMP24 ERP1 ERP2 ERV25 ERV46 NUP120 NUP145 NUP84 NUP85 SAR1 SEC13 SEC16 SEC23 SEC24 SEC31 SEH1
    View Details Krogan NJ, et al. (2006) SEC1 SEC13 SEC31
    View Details Gavin AC, et al. (2006) NUP120 NUP145 NUP84 NUP85 SEC13 SEC16 SEC23 SEC24 SEH1 SFB2
    View Details Gavin AC, et al. (2002) ACT1 AIM31 CFT1 CFT2 CKA1 CKA2 CKB1 CLP1 DBP2 ENO2 ERO1 ERV41 ERV46 FIP1 FKS1 GLC7 HHF1, HHF2 HTA1 MPE1 MRPS28 NUP120 NUP145 NUP84 NUP85 OST1 OST6 PAP1 PCF11 PFK1 PFS2 PTA1 PTI1 REF2 RNA14 RNA15 RPP2B RSA3 SEC13 SEC16 SEC23 SEC31 SEH1 SSA3 SSU72 STM1 STT3 SWP1 SYC1 TAF6 TIF34 TIF4632 TYE7 VID24 VMR1 VPS53 WBP1 YCL046W YSH1 YTH1
    View Details Ho Y, et al. (2002) ADE13 NUP133 NUP145 NUP84 NUP85 SEC13 SEC31 SEH1 YHL039W
    View Details Qiu et al. (2008) ARF1 COP1 EMP24 ERP1 ERP2 ERV25 ERV46 GLE2 GLO3 NIC96 NSP1 NUP1 NUP100 NUP116 NUP120 NUP145 NUP157 NUP170 NUP2 NUP42 NUP49 NUP53 NUP57 NUP82 NUP84 NUP85 POM152 SAR1 SEC13 SEC16 SEC23 SEC24 SEC27 SEC31 SEH1 SFB2 SFB3 YIF1 YOS1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SEC24 and SEC13 Huh WK, et al. (2003)
    View Data SEC13 Huh WK, et al. (2003)
    View Data SFB2 and SEC13 Huh WK, et al. (2003)
    View Data SEC31 and SEC13 Huh WK, et al. (2003)
    View Data SEC13 and SEC13 Huh WK, et al. (2003)
    View Data SFB3 and SEC13 Huh WK, et al. (2003)
    View Data SEC16 and SEC13 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..297] PSI-BLAST 126.165202 Tup1, C-terminal domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle