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Protein Overview: TYE7

General Information:
Name(s) found: TYE7 / YOR344C [SGD]
Description(s) found:
Found 31 descriptions.
SHOW ALL
  • Serine-rich protein that contains a basic-helix-loop-helix (bHLH) DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator in Ty1-mediated gene expression [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 291 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ICLink to PubMed article]
    Biological Process: transcription [IDALink to PubMed article][IGILink to PubMed article][IPILink to PubMed article]
    regulation of transcription involved in G1/S-phase of mitotic cell cycle [IPILink to PubMed article]
    positive regulation of glycolysis [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: transcription factor activity [IDALink to PubMed article][IGILink to PubMed article][IPILink to PubMed articleLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSILDRNVR SSETTLIKPE SEFDNWLSDE NDGASHINVN KDSSSVLSAS SSTWFEPLEN  60
   61 IISSASSSSI GSPIEDQFIS SNNEESALFP TDQFFSNPSS YSHSPEVSSS IKREEDDNAL 120
  121 SLADFEPASL QLMPNMINTD NNDDSTPLKN EIELNDSFIK TNLDAKETKK RAPRKRLTPF 180
  181 QKQAHNKIEK RYRININTKI ARLQQIIPWV ASEQTAFEVG DSVKKQDEDG AETAATTPLP 240
  241 SAAATSTKLN KSMILEKAVD YILYLQNNER LYEMEVQRLK SEIDTLKQDQ K

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2002) ACT1 AIM31 CFT1 CFT2 CKA1 CLP1 ENO2 FIP1 GLC7 HHF1, HHF2 HTA1 MPE1 PAP1 PCF11 PFK1 PFS2 PTA1 PTI1 REF2 RNA14 RNA15 RSA3 SEC13 SEC31 SSA3 SSU72 SYC1 TAF6 TIF4632 TYE7 VID24 VMR1 VPS53 YCL046W YSH1 YTH1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CLN3 TYE7 2 Unpublished Fields Lab Data
    View Screen HOF1 TYE7 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data TYE7 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..177] MSA 16.248997 View MSA. No confident structure predictions are available.
    2 View Details [178..291] PSI-BLAST 45.70927 SREBP-1a
    3 View Details [178..291] PSI-BLAST 19.39794 Myc prot-oncogene protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • transcription regulator activity
    		•  5.38658950816179 bayes_pls_golite062009
  • DNA binding
    		•  4.94162117310222 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.64041369991064 bayes_pls_golite062009
  • transcription factor activity
    		•  4.57572673546692 bayes_pls_golite062009
  • binding
    		•  3.81829206350975 bayes_pls_golite062009
  • protein binding
    		•  2.64975291677725 bayes_pls_golite062009
  • transcription factor binding
    		•  2.61163564741984 bayes_pls_golite062009
  • transcription activator activity
    		•  2.5495467409976 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.48787404513864 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.23044824326772 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity, enhancer binding
    		•  2.07158271414494 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.52770895937238 bayes_pls_golite062009
  • promoter binding
    		•  1.21602136735201 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.955588849035129 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.672485914465871 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.53175615551166 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.3655541712365 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.3513586903977 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.29436315000437 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.20674648626116 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle