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Protein Overview: EMP24

General Information:
Name(s) found: EMP24 / YGL200C [SGD]
Description(s) found:
Found 31 descriptions.
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  • Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 203 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISSLink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    ER to Golgi transport vesicle [IDALink to PubMed article]
    Biological Process: ER to Golgi vesicle-mediated transport [IMPLink to PubMed article][IPILink to PubMed article]
    vesicle organization [IGILink to PubMed article][IMPLink to PubMed article]
    protein retention in ER lumen [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASFATKFVI ACFLFFSASA HNVLLPAYGR RCFFEDLSKG DELSISFQFG DRNPQSSSQL  60
   61 TGDFIIYGPE RHEVLKTVRD TSHGEITLSA PYKGHFQYCF LNENTGIETK DVTFNIHGVV 120
  121 YVDLDDPNTN TLDSAVRKLS KLTREVKDEQ SYIVIRERTH RNTAESTNDR VKWWSIFQLG 180
  181 VVIANSLFQI YYLRRFFEVT SLV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) EMP24 ERP1 ERP2 ERV25
    View Details (MIPS) Mewes HW, et al. (2004) EMP24 ERP1 ERP2 ERV25 ERV46 SAR1 SEC13 SEC16 SEC23 SEC24 SEC31
    View Details Krogan NJ, et al. (2006) EMP24 ERP1 ERP2 KAR2 PHB2 SCJ1 SSS1 YEL1
    View Details Gavin AC, et al. (2006) EMP24 ERP1 ERP2 ERV25
    View Details Gavin AC, et al. (2002) ARO1 ARX1 EMP24 ERP1 ERP2 ERV25 FKS1 HAS1 HHF1, HHF2 KAP123 NIP7 PHB1 RRP1
    View Details Ho Y, et al. (2002) EMP24 KGD1 KRE6 RPN1 RPN12 RPN5 RPN6 RPN8 RPN9 RPT1 RPT2
    View Details Qiu et al. (2008) EMP24 ERP1 ERP2 ERV25 ERV41 ERV46 RER1 SAR1 SEC13 SEC16 SEC23 SEC24 SEC31 SFB3 SVP26 VRG4 YIP3 YOS1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen RAD6 EMP24 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data EMP24 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] Pfam 81.387216 emp24/gp25L/p24 family/GOLD No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • voltage-gated cation channel activity
    		•  2.66540214971227 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  2.66283817406605 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  2.65916906094646 bayes_pls_golite062009
  • channel activity
    		•  2.65916906094646 bayes_pls_golite062009
  • cation channel activity
    		•  2.62747969257897 bayes_pls_golite062009
  • potassium channel activity
    		•  2.61371256192732 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  2.60719363833593 bayes_pls_golite062009
  • ion channel activity
    		•  2.60082350471123 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  2.58448165457823 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  2.57450407680312 bayes_pls_golite062009
  • gated channel activity
    		•  2.51455369837435 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  2.48447488950861 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  2.48200622858578 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  2.48200622858578 bayes_pls_golite062009
  • transporter activity
    		•  2.35657262831396 bayes_pls_golite062009
  • clathrin binding
    		•  2.30826135071113 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.25147059981728 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.22751878261824 bayes_pls_golite062009
  • binding
    		•  2.16129867759095 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.14804562881998 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.08500207462933 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.02275538762334 bayes_pls_golite062009
  • inward rectifier potassium channel activity
    		•  1.9397436784802 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.58932339453245 bayes_pls_golite062009
  • signal transducer activity
    		•  1.58932339453245 bayes_pls_golite062009
  • protein binding
    		•  1.40069187357924 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.921436605338431 bayes_pls_golite062009
  • actin binding
    		•  0.852579554611056 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle