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Protein Overview: ERV25

General Information:
Name(s) found: ERV25 / YML012W [SGD]
Description(s) found:
Found 20 descriptions.
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  • Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family involved in endoplasmic reticulum to Golgi transport [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 211 amino acids

    Gene Ontology:
    Cellular Component: ER to Golgi transport vesicle [IDALink to PubMed article]
    Biological Process: ER to Golgi vesicle-mediated transport [IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVLQLWLTT LISLVVAVQG LHFDIAASTD PEQVCIRDFV TEGQLVVADI HSDGSVGDGQ  60
   61 KLNLFVRDSV GNEYRRKRDF AGDVRVAFTA PSSTAFDVCF ENQAQYRGRS LSRAIELDIE 120
  121 SGAEARDWNK ISANEKLKPI EVELRRVEEI TDEIVDELTY LKNREERLRD TNESTNRRVR 180
  181 NFSILVIIVL SSLGVWQVNY LKNYFKTKHI I

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) EMP24 ERP1 ERP2 ERV25
    View Details (MIPS) Mewes HW, et al. (2004) EMP24 ERP1 ERP2 ERV25 ERV46 SAR1 SEC13 SEC16 SEC23 SEC24 SEC31
    View Details Krogan NJ, et al. (2006) CTP1 ERV25 FKS1 FTR1 MRH1 OLE1 PEX27 ROG3 RPL10 RPL36B RPL37A RPP1A SEC11 SPC1 SPC2 SPC3 TCM62 TSC13 YNR021W
    View Details Gavin AC, et al. (2006) EMP24 ERP1 ERP2 ERV25
    View Details Gavin AC, et al. (2002) ARO1 ARX1 EMP24 ERP1 ERP2 ERV25 FKS1 GPI10 HAS1 HHF1, HHF2 KAP123 NIP7 PHB1 RRP1
    View Details Qiu et al. (2008) ARF1 EMP24 ERP1 ERP2 ERP3 ERV25 ERV46 SAR1 SEC13 SEC16 SEC23 SEC24 SEC31 SED4 SFB2 SFB3 SVP26 YOS1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run STU1 No Comments Cheeseman IM, et al. (2002)
    View Run TOR2 No Comments Reinke A, et al. (2004)
    View Run VAM3 Sample: HX14 - mixture in detergent (control). Hao Xu, et al. (2010)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data ERV25 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..211] Pfam 82.283997 emp24/gp25L/p24 family/GOLD No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle