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Protein Overview: FTR1

General Information:
Name(s) found: FTR1 / YER145C [SGD]
Description(s) found:
Found 27 descriptions.
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  • High affinity iron permease involved in the transport of iron across the plasma membrane; forms complex with Fet3p; expression is regulated by iron [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 404 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDALink to PubMed articleLink to PubMed article]
    Biological Process: high-affinity iron ion transport [IDALink to PubMed article][IMPLink to PubMed articleLink to PubMed article]
    Molecular Function: iron ion transmembrane transporter activity [IDALink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNKVFNVAV FFVVFRECLE AVIVISVLLS FLKQAIGEHD RALYRKLRIQ VWVGVLLGFI  60
   61 ICLAIGAGFI GAYYSLQKDI FGSAEDLWEG IFCMIATIMI SMMGIPMLRM NKMQSKWRVK 120
  121 IARSLVEIPH RKRDYFKIGF LSRRYAMFLL PFITVLREGL EAVVFVAGAG ITTQGSHASA 180
  181 YPLPVVVGLI CGGLVGYLLY YGASKSSLQI FLILSTSILY LISAGLFSRG AWYFENYRFN 240
  241 LASGGDASEG GDGNGSYNIR KAVYHVNCCN PELDNGWDIF NALLGWQNTG YLSSMLCYNI 300
  301 YWLVLIIVLS LMIFEERRGH LPFTKNLQLK HLNPGYWIKN KKKQELTEEQ KRQLFAKMEN 360
  361 INFNEDGEIN VQENYELPEQ TTSHSSSQNV ATDKEVLHVK ADSL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CTP1 ERV25 FKS1 FTR1 MRH1 OLE1 PEX27 ROG3 RPL10 RPL36B RPL37A RPP1A SEC11 SPC1 SPC2 SPC3 TCM62 TSC13 YNR021W
    View Details Qiu et al. (2008) ARN2 FET3 FTR1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data FTR1 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..323] Pfam 143.886057 Iron permease FTR1 family No confident structure predictions are available.
    2 View Details [324..404] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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