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Protein Overview: MRH1

General Information:
Name(s) found: MRH1 / YDR033W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 320 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    plasma membrane [IDALink to PubMed articleLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTFETLIKR GGNEAIKINP PTGADFHITS RGSDWFWTCF CCYLLFGLIL TFLMFRKPVN  60
   61 DRFFYLTGIA PNFFMCIAYF TMASNLGWIP VKAKYNHVQT STQKEHPGYR QIFYSRFVGW 120
  121 FLALPWPIIQ ICMLAGTPFW QMAFNVCITE FFTVCWLIAA CVHSTYKWGY YTIGLGAAIV 180
  181 VSISVMTTSY NLVKQRDNDI RLTFLVFFSI IMFLWIIAYP TCFGITDGGN VLQPDSAGIF 240
  241 YGIIDLILMC FIPTLLVPIA NHFGADKLGY HFGPSDAEAV MAPKAPVASP RPAATPNLSK 300
  301 DKKKKSKKSK KSKKSKKSEE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CTP1 ERV25 FKS1 FTR1 MRH1 OLE1 PEX27 ROG3 RPL10 RPL36B RPL37A RPP1A SEC11 SPC1 SPC2 SPC3 TCM62 TSC13 YNR021W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run DAD1 Dam1-765 complex purified from yeast with Dad1-TAP Shimogawa MM, et al. (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #10 Mitotic Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #06 Alpha Factor Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data MRH1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..86] PSI-BLAST 85.70927 Sensory rhodopsin II
    2 View Details [87..320] PSI-BLAST 85.70927 Sensory rhodopsin II

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor activity
    		•  5.1157224036515 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  4.85722830910254 bayes_pls_golite062009
  • signal transducer activity
    		•  4.75286640345932 bayes_pls_golite062009
  • molecular transducer activity
    		•  4.75286640345932 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  4.35314551656946 bayes_pls_golite062009
  • peptide receptor activity
    		•  2.68526520969168 bayes_pls_golite062009
  • peptide receptor activity, G-protein coupled
    		•  2.66975845749013 bayes_pls_golite062009
  • binding
    		•  2.36534865182258 bayes_pls_golite062009
  • neurotransmitter receptor activity
    		•  2.27610825294925 bayes_pls_golite062009
  • neurotransmitter binding
    		•  2.21173097508311 bayes_pls_golite062009
  • peptide binding
    		•  1.89527944834672 bayes_pls_golite062009
  • photoreceptor activity
    		•  1.79236208142167 bayes_pls_golite062009
  • G-protein coupled photoreceptor activity
    		•  1.68412761754563 bayes_pls_golite062009
  • neuropeptide receptor activity
    		•  1.58990466088334 bayes_pls_golite062009
  • neuropeptide binding
    		•  1.58990466088334 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.31009205588407 bayes_pls_golite062009
  • G-protein coupled amine receptor activity
    		•  1.2298526499749 bayes_pls_golite062009
  • protein binding
    		•  0.516440306486999 bayes_pls_golite062009
  • opioid receptor activity
    		•  0.470988413972081 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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