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View Structure Prediction Details

Protein: MRH1
Organism: Saccharomyces cerevisiae
Length: 320 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MRH1.

Description E-value Query
Range		 Subject
Range
MRH1 - Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the aut...
gi|190404995 - gi|190404995|gb|EDV08262.1| protein YRO2 [Saccharomyces cerevisiae RM11-1a]
MRH1_YEAST - Protein MRH1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MRH1 PE=1 SV=1
gi|151942019 - gi|151942019|gb|EDN60375.1| Hsp30p-like membrane protein [Saccharomyces cerevisiae YJM789]
 5.0E-89 [1..298] [1..298]
F123_CORVE - (O74631) Protein FDD123 (CvHSP30/1)
FD123_TRAVE - Protein FDD123 OS=Trametes versicolor GN=FDD123 PE=2 SV=1
 7.0E-60 [12..295] [2..275]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 9.0E-54 [13..275] [8..260]
gi|9858875 - gi|9858875|gb|AAG01180.1|AF290180_1 opsin [Leptosphaeria maculans]
 8.0E-53 [20..261] [39..283]
BACR2_HALS2 - Archaerhodopsin-2 OS=Halobacterium sp. (strain aus-2) PE=1 SV=1
gi|99215 - pir||S14731 bacteriorhodopsin precursor [validated] - Halobacterium sp. (strain aus-2)
 4.0E-50 [13..257] [1..235]
BACR3_HALSD - Archaerhodopsin-3 OS=Halorubrum sodomense GN=aop3 PE=3 SV=1
 7.0E-50 [13..257] [1..234]

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Predicted Domain #1
Region A:
Residues: [1-86] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTFETLIKR GGNEAIKINP PTGADFHITS RGSDWFWTCF CCYLLFGLIL TFLMFRKPVN  60
   61 DRFFYLTGIA PNFFMCIAYF TMASNL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.70927
Match: 1gu8A_
Description: Sensory rhodopsin II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
receptor activity 5.1157224036515 bayes_pls_golite062009
transmembrane receptor activity 4.85722830910254 bayes_pls_golite062009
signal transducer activity 4.75286640345932 bayes_pls_golite062009
molecular transducer activity 4.75286640345932 bayes_pls_golite062009
G-protein coupled receptor activity 4.35314551656946 bayes_pls_golite062009
peptide receptor activity 2.68526520969168 bayes_pls_golite062009
peptide receptor activity, G-protein coupled 2.66975845749013 bayes_pls_golite062009
binding 2.36534865182258 bayes_pls_golite062009
neurotransmitter receptor activity 2.27610825294925 bayes_pls_golite062009
neurotransmitter binding 2.21173097508311 bayes_pls_golite062009
peptide binding 1.89527944834672 bayes_pls_golite062009
photoreceptor activity 1.79236208142167 bayes_pls_golite062009
G-protein coupled photoreceptor activity 1.68412761754563 bayes_pls_golite062009
neuropeptide receptor activity 1.58990466088334 bayes_pls_golite062009
neuropeptide binding 1.58990466088334 bayes_pls_golite062009
transcription regulator activity 1.31009205588407 bayes_pls_golite062009
G-protein coupled amine receptor activity 1.2298526499749 bayes_pls_golite062009
protein binding 0.516440306486999 bayes_pls_golite062009
opioid receptor activity 0.470988413972081 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [87-320] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GWIPVKAKYN HVQTSTQKEH PGYRQIFYSR FVGWFLALPW PIIQICMLAG TPFWQMAFNV  60
   61 CITEFFTVCW LIAACVHSTY KWGYYTIGLG AAIVVSISVM TTSYNLVKQR DNDIRLTFLV 120
  121 FFSIIMFLWI IAYPTCFGIT DGGNVLQPDS AGIFYGIIDL ILMCFIPTLL VPIANHFGAD 180
  181 KLGYHFGPSD AEAVMAPKAP VASPRPAATP NLSKDKKKKS KKSKKSKKSK KSEE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 85.70927
Match: 1gu8A_
Description: Sensory rhodopsin II
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle