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Combining with epinephrine or norepinephrine to initiate a change in cell activity. Combining with the biogenic amine serotonin, a neurotransmitter and hormone found in vertebrates, invertebrates and plants, to initiate a change in cell activity. A receptor that binds an extracellular ligand and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers. Combining with the neurotransmitter dopamine to initiate a change in cell activity. Combining with the biogenic amine octopamine to initiate a change in cell activity. Octopamine is found in both vertebrates and invertebrates and can have properties both of a hormone and a neurotransmitter and acts as an adrenergic agonist. Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine. Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. A receptor that binds an extracellular amine and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers. Combining with acetylcholine to initiate a change in cell activity via activation of a G protein. null Combining with an extracellular or intracellular messenger to initiate a change in cell activity, and spanning to the membrane of either the cell or an organelle.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: G-protein coupled amine receptor activity
Acc: GO:0008227
Aspect: Molecular Function
Desc: A receptor that binds an extracellular amine and transmits the signal to a heterotrimeric G-protein complex. These receptors are characteristically seven-transmembrane receptors and are made up of hetero- or homodimers.
Synonyms:
  • biogenic amine receptor
Proteins in PDR annotated with:
   This term: 34 [Search]
   Term or descendants: 159 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008227 - G-protein coupled amine receptor activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle