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Protein Overview: OST6

General Information:
Name(s) found: OST6 / YML019W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; similar to and partially functionally redundant with Ost3p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 332 amino acids

    Gene Ontology:
    Cellular Component: oligosaccharyltransferase complex [IPILink to PubMed articleLink to PubMed article]
    Biological Process: protein complex assembly [IMPLink to PubMed article]
    protein amino acid N-linked glycosylation via asparagine [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: dolichyl-diphosphooligosaccharide-protein glycotransferase activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKWCSTYIII WLAIIFHKFQ KSTATASHNI DDILQLKDDT GVITVTADNY PLLSRGVPGY  60
   61 FNILYITMRG TNSNGMSCQL CHDFEKTYHA VADVIRSQAP QSLNLFFTVD VNEVPQLVKD 120
  121 LKLQNVPHLV VYPPAESNKQ SQFEWKTSPF YQYSLVPENA ENTLQFGDFL AKILNISITV 180
  181 PQAFNVQEFV YYFVACMVVF IFIKKVILPK VTNKWKLFSM ILSLGILLPS ITGYKFVEMN 240
  241 AIPFIARDAK NRIMYFSGGS GWQFGIEIFS VSLMYIVMSA LSVLLIYVPK ISCVSEKMRG 300
  301 LLSSFLACVL FYFFSYFISC YLIKNPGYPI VF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) OST1 OST2 OST3 OST4 OST5 OST6 STT3 SWP1 WBP1
    View Details Gavin AC, et al. (2002) ERO1 OST1 OST6 SEC13 SEH1 STT3 SWP1 TIF34 WBP1
    View Details Qiu et al. (2008) OST1 OST2 OST3 OST4 OST5 OST6 STT3 SWP1 WBP1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..74] MSA 1.013984 View MSA. Confident ab initio structure predictions are available.
    2 View Details [75..332] MSA 2.015924 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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