Protein Overview: SNU71

General Information:
Name(s) found:	SNU71 / YGR013W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6321450\|ref\|NP_011527.1\| Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; Snu71p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S64304 hypothetical protein YGR013w - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1723645\|sp\|P53207.1\|SNU71_YEAST RecName: Full=U1 small nuclear ribonucleoprotein component SNU71 [NCBI NR] gi\|1322976\|emb\|CAA96996.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] Uncharacterized protein YGR013W - Saccharomyces cerevisiae (Baker's yeast) [Swiss-Prot] U1 small nuclear ribonucleoprotein component SNU71 OS=Saccharomyces cerevisiae GN=SNU71 PE=1 SV=1 [Swiss-Prot] SNU71 Associated with U1 snRNP, no counterpart in mammalian U1 snRNP [mips] Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart [SGD] SNU71, Chr VII from 514548-516410 [yeast_orfs2] Chr VII from 514548-516410 [yeastorf3.fasta] Chr VII from 514555-516417 [yeastorf4.fasta] (P53207) Hypothetical 71.4 kDa protein in SEC9-MSB2 intergenic region [4932.FASTACCERV.txt] SNU71 SGDID:S0003245, Chr VII from 514556-516418, Verified ORF [yeastflysequest.fasta] SNU71 SGDID:S0003245, Chr VII from 514558-516420, Verified ORF [10112005cervSGD.fasta] Snu71p [Saccharomyces cerevisiae]gi\|1322976\|emb\|CAA96996.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|2131642\|pir\|\|S64304 hypothetical protein YGR013w - yeast (Saccharomyces cerevisiae)gi\|1723645\|sp\|P53207\|YG18_YEAST Hypothetical 71.4 kDa pr [nrdb_11152004_Chlamydomonas] SNU71 SGDID:S000003245, Chr VII from 514558-516420, Verified ORF, "Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Uncharacterized protein YGR013W [nr-271106-contam.fasta] Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; Snu71p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] U1 small nuclear ribonucleoprotein component SNU71 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SNU71 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] SNU71 SGDID:S000003245, Chr VII from 514554-516416, Genome Release 64-1-1, Verified ORF, "Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart" [yeast-030211-contam.fasta] SNU71 SGDID:S000003245, Chr VII from 514554-516416, Genome Release 64-2-1, Verified ORF, "Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart" [20141208_orf_trans.fasta] YGR013W SGDID:S000003245, Chr VII from 514554-516416, Genome Release 64-1-1, Verified ORF, "Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	620 amino acids
Gene Ontology:
Cellular Component:	U1 snRNP [IDA ]
Biological Process:	nuclear mRNA splicing, via spliceosome [IPI]
Molecular Function:	RNA binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRDIVFVSPQ LYLSSQEGWK SDSAKSGFIP ILKNDLQRFQ DSLKHIVDAR NSLSETLLNS  60
   61 NDDGSIHNSD QNTGLNKDKE ASIADNNSAN KCATSSSRYQ ELKQFLPISL DQQIHTVSLQ 120
  121 GVSSSFSRGQ IESLLDHCLN LALTETQSNS ALKVEAWSSF SSFLDTQDIF IRFSKVDEDE 180
  181 AFVNTLNYCK ALFAFIRKLH EDFKIELHLD LNTKEYVEDR TGTIPSVKPE KASEFYSVFK 240
  241 NIEDQTDERN SKKEQLDDSS TQYKVDTNTL SDLPSDALDQ LCKDIIEFRT KVVSIEKEKK 300
  301 MKSTYEESRR QRHQMQKVFD QIRKNHSGAK GSANTEEEDT NMEDEDEEDD TEDDLALEKR 360
  361 KEERDLEESN RRYEDMLHQL HSNTEPKIKS IRADIMSAEN YEEHLEKNRS LYLKELLHLA 420
  421 NDVHYDHHRS FKEQEERRDE EDRAKNGNAK ELAPIQLSDG KAISAGKAAA ITLPEGTVKS 480
  481 ENYNADKNVS ESSEHVKIKF DFKKAIDHSV ESSSEDEGYR ESELPPTKPS ERSAAEDRLP 540
  541 FTADELNIRL TNLKESRYVD ELVREFLGVY EDELVEYILE NIRVNQSKQA LLNELRETFD 600
  601 EDGETIADRL WSRKEFRLGT

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		BRR1 BRR2 CBC2 CSN12 CUS1 DIB1 HSH155 LEA1 LUC7 MUD1 NAM8 PRP19 PRP3 PRP31 PRP39 PRP4 PRP40 PRP42 PRP6 PRP8 PRP9 RSE1 SMB1 SMD1 SMD2 SMD3 SME1 SMX3 SNP1 SNU114 SNU56 SNU71 SPP382 STO1 YHC1
View Details	Krogan NJ, et al. (2006)		AAR2 BRR1 BRR2 CSE1 LUC7 MUD1 NAM8 PRP2 PRP3 PRP31 PRP39 PRP40 PRP42 PRP6 PRP8 RRG7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNU114 SNU56 SNU66 SNU71 TAD2 YDL085C-A YHC1 YJU2 YNL092W
View Details	Gavin AC, et al. (2006)		LUC7 MUD1 NAM8 PRP39 PRP40 PRP42 SNP1 SNU56 SNU71 YHC1
View Details	Gavin AC, et al. (2002)		AAR2 AIR2 ATP8 BRR1 BUD31 BUR2 CBC2 CDC33 CEF1 CLF1 CSN12 CUS1 CWC2 CWC22 CWC23 DHH1 DIB1 ECM2 GCN2 HRT1 HSH155 HSH49 HTA1 IMG1 KAP95 LEA1 LIN1 LSM1 LSM2 LSM4 LSM5 LSM6 LSM7 LUC7 MRP7 MRPL28 MRPL3 MRPL35 MRPL38 MRPL4 MRPL8 MRPS5 MSH4 MSL1 MUD1 NAB3 NAB6 NAM8 NPL3 NRD1 NUP60 PAT1 PEP3 PEP5 PRP11 PRP18 PRP19 PRP21 PRP24 PRP28 PRP3 PRP31 PRP38 PRP39 PRP4 PRP40 PRP42 PRP43 PRP46 PRP6 PRP8 PRP9 RSE1 RVB2 SCP160 SEN1 SGV1 SLU7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNT309 SNU114 SNU23 SNU56 SNU66 SNU71 SPP381 SPP382 SRB2 SRO9 SRP1 STO1 SYF1 THO2 TIF4631 TIF4632 TOS4 UTP21 VAM6 VPS16 VPS33 VPS41 VPS8 YEF3 YML6 YRA2
View Details	Qiu et al. (2008)		AAR2 BRR1 BRR2 CBC2 CDC40 CEF1 CLF1 CUS1 CUS2 CWC15 CWC2 CWC22 CWC23 DIB1 HSH155 HSH49 IST3 ISY1 LEA1 LSM4 LSM7 LSM8 LUC7 MAK5 MSL1 MUD1 MUD2 NTC20 PRP11 PRP16 PRP18 PRP19 PRP2 PRP21 PRP22 PRP24 PRP28 PRP3 PRP31 PRP38 PRP39 PRP4 PRP40 PRP42 PRP43 PRP5 PRP6 PRP8 PRP9 RSE1 SLU7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNT309 SNU114 SNU23 SNU66 SNU71 SPP2 SPP381 SPP382 STO1 SUB2 SYF1 SYF2 YHC1

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	CEP3	sample cbf3 from feb 2005	Sandall S, et all (2006)
View Run	RLF2	phosphorylation data - cascade search	Green EM, et al (2005)
View Run	MLP2	#12 Mitotic Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)
View Run	MLP2	#11 Mitotic Prep1-TiO2 enriched, new search criteria	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	PRP40	SNU71	2	Unpublished Fields Lab Data
View Screen	PRP40	SNU71	2	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	SNU71	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..383]	PSI-BLAST	20.154902	Heavy meromyosin subfragment
2	View Details	[384..620]	MSA	5.195997	View MSA. No confident structure predictions are available.
3	View Details	[521..620]	FFAS03	3.15	Solution structure of the PWI motif from SRm160

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2