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Protein Overview: SNT309

General Information:
Name(s) found: SNT309 / YPR101W [SGD]
Description(s) found:
Found 29 descriptions.
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  • Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; interacts physically and genetically with Prp19p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 175 amino acids

    Gene Ontology:
    Cellular Component: spliceosomal complex [IDALink to PubMed article]
    Biological Process: nuclear mRNA splicing, via spliceosome [IGILink to PubMed article][IMPLink to PubMed article][IPILink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGLSFVDKG KIPDGYKNEI DQLVKKEFAN IKREPVHPEI RGILAKRKGA DNSVSTLTNA  60
   61 LYTEYLKQRN NKKRRTPDFN DDDDTLFLEE YRRKYPRIDT SRYIPNESSE VSLLGIVDSY 120
  121 LKHQEIVLDT LLPQTVSNQW RINNDYIRQT CTIVEEMNIQ QRKQINDLEI YRKRL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) BRR2 BUD31 CDC40 CEF1 CLF1 CWC2 CWC22 CWC23 DIB1 ECM2 HSH155 ISY1 LEA1 PRP19 PRP43 PRP45 PRP46 PRP8 PRP9 RSE1 SMB1 SNT309 SNU114 SPP382 STO1 SYF1
    View Details Hazbun TR, et al. (2003) BRR2 CDC40 CEF1 CLF1 CWC2 CWC22 CWC23 ECM2 ISY1 LEA1 NTR2 PRP19 PRP43 PRP45 PRP46 PRP8 SMB1 SMD1 SMD3 SMX3 SNT309 SNU114 SPP382 SYF1 SYF2 YJU2
    View Details (MIPS) Mewes HW, et al. (2004) PRP19 PRP21 SNT309
    View Details Krogan NJ, et al. (2006) CEF1 CLF1 ISY1 NTC20 SEC6 SNT309 SYF1 SYF2
    View Details Gavin AC, et al. (2002) AAR2 BRR1 BUD31 CBC2 CDC33 CDC40 CEF1 CLF1 CSN12 CUS1 CWC2 CWC22 CWC23 DHH1 DIB1 ECM2 GCN2 HRT1 HSH155 HSH49 HTA1 IMG1 ISY1 LEA1 LIN1 LSM1 LSM2 LSM4 LSM5 LSM6 LSM7 LUC7 MRP7 MRPL28 MRPL3 MRPL35 MRPL38 MRPL4 MRPL8 MRPS5 MSL1 MUD1 NAM8 NPL3 PAT1 PRP11 PRP18 PRP19 PRP2 PRP21 PRP22 PRP24 PRP28 PRP3 PRP31 PRP38 PRP39 PRP4 PRP40 PRP42 PRP43 PRP45 PRP46 PRP6 PRP8 PRP9 RSE1 RVB2 SLU7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNT309 SNU114 SNU23 SNU56 SNU66 SNU71 SPP381 SPP382 SRB2 STO1 SYF1 TIF4631 TIF4632 TOS4 UTP21 YEF3 YML6
    View Details Ho Y, et al. (2002) CEF1 CLF1 PRP19 SNT309
    View Details Qiu et al. (2008) AAR2 BRR1 BRR2 CBC2 CDC40 CEF1 CLF1 CUS1 CWC15 CWC2 CWC22 CWC23 DIB1 HSH155 ISY1 LEA1 LSM2 LSM3 LSM4 LSM5 LSM7 LUC7 MAK5 MSL1 MUD1 MUD2 NTC20 PRP16 PRP18 PRP19 PRP2 PRP21 PRP22 PRP24 PRP28 PRP31 PRP38 PRP39 PRP4 PRP40 PRP42 PRP43 PRP5 PRP6 PRP8 PRP9 RSE1 SLU7 SMB1 SMD1 SMD3 SME1 SMX2 SMX3 SNP1 SNT309 SNU114 SNU56 SNU71 SPP2 SPP381 SPP382 STO1 SUB2 SYF2 YHC1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CWC2 No Comments Hazbun TR, et al. (2003)
    View Run YLR132C No Comments Hazbun TR, et al. (2003)
    View Run SPP382 No Comments Hazbun TR, et al. (2003)
    View Run CWC25 No Comments Hazbun TR, et al. (2003)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SNT309 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..175] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle