Bait Protein: | CWC25 |
Organism: | Saccharomyces cerevisiae |
Publication: | Hazbun TR, et al. (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65 |
Comments: | No comments. |
Raw Data: |
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FILTERED Run Results:
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Hit Protein | Protein Desc | Sequence Count | Spectrum Count | Sequence Coverage | NSAF | Mol. Wt. | |
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CWC25 | Heat-stable protein required for the first step of pre-mRNA splicing; component of a complex contain... | 9 | 25 | 45.8% | 0.202 | 20374 |
[ |
SNT309 | Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... | 4 | 16 | 42.9% | 0.132 | 20709 |
[ |
PRP19 | Splicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiqu... | 14 | 30 | 41.9% | 0.0862 | 56570 |
[ |
SMD1 | Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and... | 3 | 9 | 34.2% | 0.0891 | 16275 |
[ |
CLF1 | Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... | 9 | 14 | 22.4% | 0.0294 | 82445 |
[ |
LEA1 | Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically interacts with Msl1p; p... | 3 | 3 | 21.0% | 0.0182 | 27193 |
[ |
YJU2 | Essential protein required for pre-mRNA splicing; associates transiently with the spliceosomal NTC (... | 3 | 3 | 16.5% | 0.0156 | 32312 |
[ |
SYF2 | Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... | 2 | 2 | 15.8% | 0.0134 | 24803 |
[ |
ISY1 | Member of NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of ... | 2 | 6 | 15.3% | 0.0369 | 28024 |
[ |
ECM2 | Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association wit... | 3 | 4 | 15.1% | 0.0159 | 40925 |
[ |
SNU114 | GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; ... | 8 | 12 | 12.3% | 0.0172 | 114041 |
[ |
CWC22 | Essential protein, component of a complex containing Cef1p, has similarity to S. pombe Cwf22p; putat... | 5 | 7 | 12.3% | 0.0175 | 67294 |
[ |
SYF1 | Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... | 5 | 14 | 11.1% | 0.0235 | 100229 |
[ |
CWC2 | Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... | 2 | 4 | 10.9% | 0.017 | 38431 |
[ |
PRP46 | Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms... | 3 | 5 | 9.8% | 0.016 | 50700 |
[ |
CEF1 | Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb ... | 3 | 6 | 9.0% | 0.0147 | 67731 |
[ |
PRP8 | Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing; mutation... | 12 | 18 | 7.7% | 0.0108 | 279502 |
[ |
LAT1 | Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex, which catalyzes... | 2 | 3 | 7.5% | 0.00899 | 51818 |
[ |
SNX4 | Sorting nexin, involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Gol... | 2 | 2 | 7.3% | 0.00683 | 49002 |
[ |
CDC40 | Pre-mRNA splicing factor, important for catalytic step II of pre-mRNA splicing and plays a role in c... | 2 | 3 | 5.7% | 0.00953 | 52048 |
[ |
SLM1 | Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in ... | 2 | 2 | 5.2% | 0.00421 | 77995 |
[ |
STO1 | Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry nuclear... | 2 | 3 | 3.9% | 0.00503 | 100017 |
[ |
SPT5 | Protein involved in regulating Pol I and Pol II transcription and pre-mRNA processing; forms a compl... | 2 | 2 | 3.6% | 0.00272 | 115650 |
[ |
TRS130 | One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates... | 2 | 4 | 2.8% | 0.00524 | 128131 |
[ |
SMC1 | Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation an... | 2 | 2 | 2.5% | 0.00236 | 141280 |
[ |
DOP1 | Golgi-localized, leucine-zipper domain containing protein; involved in endosome to Golgi transport, ... | 2 | 2 | 1.8% | 0.0017 | 194686 |