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Protein Overview: LUC7

General Information:
Name(s) found: LUC7 / YDL087C [SGD]
Description(s) found:
Found 24 descriptions.
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  • Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 261 amino acids

    Gene Ontology:
    Cellular Component: U1 snRNP [IDALink to PubMed article][IGILink to PubMed article][IMPLink to PubMed article][ISSLink to PubMed article]
    Biological Process: mRNA splice site selection [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: mRNA binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTMSTPAAE QRKLVEQLMG RDFSFRHNRY SHQKRDLGLH DPKICKSYLV GECPYDLFQG  60
   61 TKQSLGKCPQ MHLTKHKIQY EREVKQGKTF PEFEREYLAI LSRFVNECNG QISVALQNLK 120
  121 HTAEERMKIQ QVTEELDVLD VRIGLMGQEI DSLIRADEVS MGMLQSVKLQ ELISKRKEVA 180
  181 KRVRNITENV GQSAQQKLQV CEVCGAYLSR LDTDRRLADH FLGKIHLGYV KMREDYDRLM 240
  241 KNNRTTNASK TATTLPGRRF V

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) CBC2 CSN12 DIB1 HSH155 LUC7 MUD1 NAM8 PRP11 PRP39 PRP40 PRP42 PRP8 RSE1 SMB1 SMD1 SMD2 SMD3 SNP1 SNU114 SNU56 SNU71 SPP382 STO1 TIF4632 YHC1
    View Details Krogan NJ, et al. (2006) AAR2 BRR1 BRR2 CSE1 LUC7 MUD1 NAM8 PRP2 PRP3 PRP31 PRP39 PRP40 PRP42 PRP6 PRP8 RRG7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNU114 SNU56 SNU66 SNU71 TAD2 YDL085C-A YHC1 YJU2 YNL092W
    View Details Gavin AC, et al. (2006) LUC7 MUD1 NAM8 PRP39 PRP40 PRP42 SNP1 SNU56 SNU71 YHC1
    View Details Gavin AC, et al. (2002) AAR2 AIR2 ATP8 BRR1 BUD31 BUR2 CBC2 CDC33 CEF1 CLF1 CSN12 CUS1 CWC2 CWC22 CWC23 DHH1 DIB1 ECM2 GCN2 HRT1 HSH155 HSH49 HTA1 IMG1 KAP95 LEA1 LIN1 LSM1 LSM2 LSM4 LSM5 LSM6 LSM7 LUC7 MRP7 MRPL28 MRPL3 MRPL35 MRPL38 MRPL4 MRPL8 MRPS5 MSH4 MSL1 MUD1 NAB3 NAB6 NAM8 NPL3 NRD1 NUP60 PAT1 PEP3 PEP5 PRP11 PRP18 PRP19 PRP21 PRP24 PRP28 PRP3 PRP31 PRP38 PRP39 PRP4 PRP40 PRP42 PRP43 PRP46 PRP6 PRP8 PRP9 RSE1 RVB2 SCP160 SEN1 SGV1 SLU7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNT309 SNU114 SNU23 SNU56 SNU66 SNU71 SPP381 SPP382 SRB2 SRO9 SRP1 STO1 SYF1 THO2 TIF4631 TIF4632 TOS4 UTP21 VAM6 VPS16 VPS33 VPS41 VPS8 YEF3 YML6 YRA2
    View Details Qiu et al. (2008) AAR2 BRR1 BRR2 CBC2 CDC40 CLF1 CUS1 CUS2 CWC15 CWC2 CWC22 CWC23 CWC25 DHR2 DIB1 ECM2 HSH155 HSH49 IST3 LEA1 LSM2 LSM3 LSM4 LUC7 MAK5 MSL1 MUD1 MUD2 NAM8 NTC20 PRP11 PRP16 PRP18 PRP19 PRP2 PRP21 PRP22 PRP24 PRP28 PRP3 PRP31 PRP38 PRP39 PRP4 PRP40 PRP42 PRP43 PRP46 PRP5 PRP6 PRP8 PRP9 RSE1 SLU7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNT309 SNU114 SNU23 SNU56 SNU66 SNU71 SPP2 SPP381 SPP382 STO1 SUB2 SYF2 YHC1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SPO21 LUC7 2 Unpublished Fields Lab Data
    View Screen TIP41 LUC7 2 Unpublished Fields Lab Data
    View Screen PRP40 LUC7 2 Unpublished Fields Lab Data
    View Screen PRP40 LUC7 1 Unpublished Fields Lab Data
    View Screen TOP3 LUC7 1 Unpublished Fields Lab Data
    View Screen UBC7 LUC7 1 Unpublished Fields Lab Data
    View Screen YNL311C LUC7 1 Unpublished Fields Lab Data
    View Screen MRPL51 LUC7 1 Unpublished Fields Lab Data
    View Screen ILM1 LUC7 1 Lockshon D, et al. (2006)
    View Screen KSS1 LUC7 1 Unpublished Fields Lab Data
    View Screen IST3 LUC7 1 Unpublished Fields Lab Data
    View Screen TRL1 LUC7 1 Unpublished Fields Lab Data
    View Screen DAS1 LUC7 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data LUC7 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..261] Pfam 134.886057 LUC7 N_terminus No confident structure predictions are available.
    2 View Details [68..261] FFAS03 1.51 Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle