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Recognition of the intron 5'-splice site by components of the assembling spliceosome. The aggregation, arrangement and bonding together of the spliceosome, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions. The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. The joining together of exons from one or more primary transcripts of nuclear messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced. Selection of a splice site by components of the assembling spliceosome. The cellular process by which a complex containing RNA and proteins is synthesized, aggregates, and bonds together. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex. Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome. The aggregation, arrangement and bonding together of a set of macromolecules to form a complex, carried out at the cellular level.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: mRNA splice site selection
Acc: GO:0006376
Aspect: Biological Process
Desc: Selection of a splice site by components of the assembling spliceosome.
Synonyms:
  • spliceosomal commitment complex biosynthesis
  • spliceosomal E complex biosynthesis
  • spliceosomal commitment complex formation
  • spliceosomal E complex formation
Proteins in PDR annotated with:
   This term: 30 [Search]
   Term or descendants: 55 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006376 - mRNA splice site selection (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle