YRC Public Data Repository - Protein Structure Prediction

Protein:	LUC7
Organism:	Saccharomyces cerevisiae
Length:	261 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LUC7.

Description	E-value	Query Range	Subject Range
LUC7_YEAST - Protein LUC7 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=LUC7 PE=1 SV=1 LUC7 - Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5...	5.0E-86	[1..261]	[1..261]
LUC7_SCHPO - U1 snRNP-associated protein usp106 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=usp106 ... usp106 - U1 snRNP-associated protein Usp106	2.0E-67	[8..250]	[2..239]
gi\|12846060, gi\|... - gi\|21536228\|ref\|NP_080157.1\| Luc7 homolog (S. cerevisiae)-like isoform 1 [Mus musculus], gi\|14869055...	2.0E-66	[9..250]	[5..239]
gi\|114660128 - gi\|114660128\|ref\|XP_001152163.1\| PREDICTED: hypothetical protein isoform 8 [Pan troglodytes] gi\|90653012, gi\|... - gi\|90653012\|gb\|ABD95913.1\| putative RNA-binding protein Luc7-like 1 [Homo sapiens], gi\|8922297\|ref\|N...	2.0E-66	[9..250]	[5..239]
FBpp0311537, CG7... - This gene is referred to in FlyBase by the symbol Dmel\CG7564 (CG7564, FBgn0036734). It is a protein...	8.0E-65	[10..249]	[13..243]

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Predicted Domain #1

Region A:
Residues: [1-261]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTMSTPAAE QRKLVEQLMG RDFSFRHNRY SHQKRDLGLH DPKICKSYLV GECPYDLFQG  60
   61 TKQSLGKCPQ MHLTKHKIQY EREVKQGKTF PEFEREYLAI LSRFVNECNG QISVALQNLK 120
  121 HTAEERMKIQ QVTEELDVLD VRIGLMGQEI DSLIRADEVS MGMLQSVKLQ ELISKRKEVA 180
  181 KRVRNITENV GQSAQQKLQV CEVCGAYLSR LDTDRRLADH FLGKIHLGYV KMREDYDRLM 240
  241 KNNRTTNASK TATTLPGRRF V

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	134.886057
Match:	PF03194
Description:	LUC7 N_terminus

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [68-261]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CPQMHLTKHK IQYEREVKQG KTFPEFEREY LAILSRFVNE CNGQISVALQ NLKHTAEERM  60
   61 KIQQVTEELD VLDVRIGLMG QEIDSLIRAD EVSMGMLQSV KLQELISKRK EVAKRVRNIT 120
  121 ENVGQSAQQK LQVCEVCGAY LSRLDTDRRL ADHFLGKIHL GYVKMREDYD RLMKNNRTTN 180
  181 ASKTATTLPG RRFV

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.51
Match:	1jchA
Description:	Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits