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Protein Overview: REB1

General Information:
Name(s) found: REB1 / YBR049C [SGD]
Description(s) found:
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  • gi|6319523|ref|NP_009605.1| RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription; Reb1p [Saccharomyces ce [NCBI NR]
  • pir||S45907 myb-related protein REB1 - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|585795|sp|P21538.2|REB1_YEAST RecName: Full=DNA-binding protein REB1; AltName: Full=QBP [NCBI NR]
  • gi|559944|emb|CAA86391.1| REB1 DNA-binding protein [Saccharomyces cerevisiae] [NCBI NR]
  • gi|536280|emb|CAA84992.1| REB1 [Saccharomyces cerevisiae] [NCBI NR]
  • DNA-binding protein REB1 OS=Saccharomyces cerevisiae GN=REB1 PE=1 SV=2 [Swiss-Prot]
  • REB1 Transcription factor [mips]
  • RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription [SGD]
  • REB1, Chr II from 334345-336777, reverse complement [yeast_orfs2]
  • Chr II from 334345-336777, reverse complement [yeastorf3.fasta]
  • Chr II from 336777-334345, reverse complement [yeastorf5.fasta]
  • (P21538) DNA-binding protein REB1 (QBP) [4932.FASTACCERV.txt]
  • REB1 SGDID:S0000253, Chr II from 336778-334346, reverse complement, Verified ORF [yeastflysequest.fasta]
  • REB1 SGDID:S0000253, Chr II from 336816-334384, reverse complement, Verified ORF [10112005cervSGD.fasta]
  • RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription [Saccharomyces cerevisiae]gi|559944|emb|CAA86391.1| [nrdb_11152004_Chlamydomonas]
  • REB1 SGDID:S000000253, Chr II from 336816-334384, reverse complement, Verified ORF, "RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination o [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • REB1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • DNA-binding protein REB1 (QBP) [nr-271106-contam.fasta]
  • REB1 DNA-binding protein [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription; Reb1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • REB1 SGDID:S000000253, Chr II from 336816-334384, reverse complement, Verified ORF, "RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription" [yeast-bovrabprots.fasta]
  • [chemostatdb.fasta]
  • DNA-binding protein REB1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=REB1 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • REB1 SGDID:S000000253, Chr II from 336818-334386, Genome Release 64-1-1, reverse complement, Verified ORF, "RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription" [yeast-030211-contam.fasta]
  • REB1 SGDID:S000000253, Chr II from 336818-334386, Genome Release 64-2-1, reverse complement, Verified ORF, "RNA polymerase I enhancer binding protein; DNA binding protein that binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription; REB1 has a paralog, NSI1, that arose from the whole genome duplication" [20141208_orf_trans.fasta]
  • YBR049C SGDID:S000000253, Chr II from 336818-334386, Genome Release 64-1-1, reverse complement, Verified ORF, "RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 810 amino acids

    Gene Ontology:
    Cellular Component: nucleus [TASLink to PubMed article]
    Biological Process: termination of RNA polymerase I transcription [TASLink to PubMed article]
    regulation of transcription from RNA polymerase II promoter [TASLink to PubMed article]
    Molecular Function: RNA polymerase II transcription factor activity [IDALink to PubMed article]
    RNA polymerase I transcription termination factor activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSGHNDKNA NQESVEEAVL KYVGVGLDHQ NHDPQLHTKD LENKHSKKQN IVESSSDVDV  60
   61 NNNDDSNRNE DNNDDSENIS ALNANESSSN VDHANSNEQH NAVMDWYLRQ TAHNQQDDED 120
  121 DENNNNTDNG NDSNNHFSQS DIVVDDDDDK NKKDAGVGVD DDHQSMAMAA VAAAYTLSKN 180
  181 NNNNNSIAND SNSRKRQHDN GNNHENSQKK RKNNNDDDDR QIGNVDPELT TLGDADDNDT 240
  241 NNDVIDRDQL VHKAIIDADS ITQHPDFQQY LNTAADTDDN EKLKHIKDHL MRTHGLNHQN 300
  301 KNHNDDTDDL SNSTKQYSEL QKDSMLDSSL NKSRNYMEVL PKVISQDTQP HQQKSPSHDN 360
  361 EAGSVDNSEI SQLLQSAATK ASSLVSLSSS SATPSTSRSN NSKAFDKAED AALERFINEY 420
  421 EAIERLTRQQ VCERIWSSDR PKDNFWNNIY KVLPYRSSSS IYKHMRRKYH IFEQRGKWTA 480
  481 EEEQELAKLC AEKEGQWAEI GKTLGRMPED CRDRWRNYVK CGTNRASNRW SVEEEELLKK 540
  541 VISDMLEEAQ QQQSQLHPNL LEEEQHLLQD DQNDHRNNDE DDDDTASAAA AAAAAIQEQQ 600
  601 QLLQQKQQDD DDAIAAAAAA ASSSLGDNKD EDKPHDSLGI QLDDNSQNSM VPAPSATSTH 660
  661 SKSLSNTIRR HNNKLRKSLM GNGKLDFKDI INWTIVSERM GGTRSRIQCR YKWNKLVKRE 720
  721 AIAKIQTVKD DDMLWIFEKL RDLGITEDSQ VDWDELAALK PGMKLNGLEL KLCYERMKKK 780
  781 VKGYKQKSIN EISKELVDYF SSNISMKTEN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ASF2 BUD23 ECM16 REB1
    View Details Gavin AC, et al. (2006) ADE5,7 REB1 TOP1 VHR1
    View Details Gavin AC, et al. (2002) ADE5,7 HHF1, HHF2 IOC3 ISW1 ISW2 ITC1 MOT1 NPL6 REB1 RFA1 RFX1 RNR2 RPC34 RPC40 RPO31 RSC2 RSC3 RSC58 RSC8 RVB2 SFH1 STH1 STO1 TAF1 TFC7 TOP1 VPS1 YBR090C-A, NHP6B
    View Details Ho Y, et al. (2002) DIS3 EAF3 FIP1 HAS1 HPR1 KAP95 MES1 MFT1 NAM8 NOP6 NUP1 NUP2 NUP60 PAP1 PCT1 REB1 RNT1 RRP4 RRP43 RRP6 RTT103 SIF2 SIN3 SNU56 SRP1 STO1 THO2 TRA1 UME1 YPR090W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data REB1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..248] ORFEUS 7.26 No description for 1ldvA was found.
    2 View Details [249..373] deduced N/A No confident structure predictions are available.
    3 View Details [374..472] PSI-BLAST 89.9897 c-Myb, DNA-binding domain
    4 View Details [473..522] PSI-BLAST 89.9897 c-Myb, DNA-binding domain
    5 View Details [523..580] PSI-BLAST 89.9897 c-Myb, DNA-binding domain
    6 View Details [581..657] ORFEUS 10.4 c-Myb, DNA-binding domain
    7 View Details [658..720] ORFEUS 10.4 c-Myb, DNA-binding domain
    8 View Details [721..810] ORFEUS 10.4 c-Myb, DNA-binding domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  0.334577365229545 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0696342306231097 bayes_pls_golite062009
    4 No functions predicted.
    5
    Term Confidence Notes
  • binding
    		•  0.232528774113254 bayes_pls_golite062009
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle