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Protein Overview: ASF2

General Information:
Name(s) found: ASF2 / YDL197C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Anti-silencing protein that causes derepression of silent loci when overexpressed [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 525 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed articleLink to PubMed article]
    nuclear chromosome, telomeric region [IDALink to PubMed article]
    Biological Process: chromatin silencing at silent mating-type cassette [IGILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKNRGVLDA ITRSVIDGSD QESSSSFNSD KEYAAVTKGL SSSRVQKKSS LRQMKSKVKE  60
   61 LQSLVNHYRE NEAALVSSAK LLSGEIIGYE IKMASLHGKM KSILDENNAL KETHKSSAEK 120
  121 RIELVRLPSS KEERNYDEYT LLVNLKKEIC AKLQDYKNVQ NTVNTKLDEI HTFHEKYYEG 180
  181 LELSLDSKVF DAESSKELAK VRRELNNVRK NSEIKVNNLK MQLLQATKSL EHLKKQAKAK 240
  241 DDYLKCIPEL VDKANLTMLS YKKSIANQRE TIEALQAELS QQSETKGQIE TETQNQVQIP 300
  301 TNVTLVDPFE ENNPEDLFAI QEQELQDLRL HKKMADERSR TTHLHLERKN NTIKLLQSYV 360
  361 QSLIQRLPPA QRKHHLGIFQ KLGSEKSCPL APAVASTYAP LLLLSQHSNH QEIDNTPQRL 420
  421 LLAAPDGQSY SEKSTTLNLD YSSRKSYLSR LQPPHIANLK SLTLKTLPRV PTDSPQLPSK 480
  481 DKSQETAKKD DRPKLVANEP VTLDTSTPPV AQSLADSKHC SGLHK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ASF2 BUD23 ECM16 REB1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run NSE5 No Comments Hazbun TR, et al. (2003)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ASF2 Sundin BA, et al. (2004)
    View Data ASF2 Sundin BA, et al. (2004)
    View Data ASF2 and SPC29 Sundin BA, et al. (2004)
    View Data ASF2 and SPC29 Sundin BA, et al. (2004)
    View Data ASF2 and SPC29 Sundin BA, et al. (2004)
    View Data ASF2 and SPC29 Sundin BA, et al. (2004)
    View Data ASF2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..366] PSI-BLAST 17.69897 Heavy meromyosin subfragment
    2 View Details [367..525] MSA 6.112997 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle