Protein Overview: RSA4

General Information:
Name(s) found:	RSA4 / YCR072C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|51012783\|gb\|AAT92685.1\| YCR072C [Saccharomyces cerevisiae] [NCBI NR] gi\|32363492\|sp\|P25382.3\|YCW2_YEAST RecName: Full=WD repeat-containing protein YCR072C [NCBI NR] gi\|14588954\|emb\|CAC42989.1\| beta-transducin family (WD-40 repeat) protein [Saccharomyces cerevisiae] [NCBI NR] gi\|10383804\|ref\|NP_009997.2\| WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus; Rsa4p [Saccharomyces cere [NCBI NR] WD repeat-containing protein YCR072C OS=Saccharomyces cerevisiae GN=YCR072C PE=1 SV=3 [Swiss-Prot] RSA4 WD-repeat protein required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits [mips] WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus [SGD] YCR072C, Chr III from 240797-242344, reverse complement [yeast_orfs2] Chr III from 240797-242344, reverse complement [yeastorf3.fasta] Chr III from 242344-240797, reverse complement [yeastorf5.fasta] (P25382) Hypothetical WD-repeat protein YCR072C [4932.FASTACCERV.txt] YCR072C SGDID:S0000668, Chr III from 242347-240800, reverse complement, Uncharacterized ORF [yeastflysequest.fasta] Protein required for cell viability [Saccharomyces cerevisiae]gi\|51012783\|gb\|AAT92685.1\| YCR072C [Saccharomyces cerevisiae]gi\|14588954\|emb\|CAC42989.1\| beta-transducin family (WD-40 repeat) protein [Saccharomyces cerevisiae]gi\|32363492\|sp\|P25382\|YCW2_YE [nrdb_11152004_Chlamydomonas] RSA4 SGDID:S000000668, Chr III from 242347-240800, reverse complement, Verified ORF, "WD-repeat protein involved in ribosome biogenesis; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolu [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] RSA4 SGDID:S000000668, Chr III from 242348-240801, reverse complement, Verified ORF, "WD-repeat protein involved in ribosome biogenesis; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolu [yeast-contam.fasta] RSA4 SGDID:S000000668, Chr III from 242348-240801, reverse complement, Verified ORF, "WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subuni [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] beta-transducin family (WD-40 repeat) protein [Saccharomyces cerevisiae] [nr-271106-contam.fasta] WD-repeat protein involved in ribosome biogenesis; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus; Rsa4p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] WD repeat protein YCR072C [nr-271106-contam.fasta] YCR072C [Saccharomyces cerevisiae] [nr-271106-contam.fasta] RSA4 SGDID:S000000668, Chr III from 242348-240801, reverse complement, Verified ORF, "WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus" [yeast-bovrabprots.fasta] RSA4 SGDID:S000000668, Chr III from 242348-240801, reverse complement, Verified ORF, "WD-repeat protein involved in ribosome biogenesis; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus" [yeast-contam_custom.fasta] [chemostatdb.fasta] RSA4 SGDID:S000000668, Chr III from 242352-240805, Genome Release 64-1-1, reverse complement, Verified ORF, "WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus" [yeast-030211-contam.fasta] RSA4 SGDID:S000000668, Chr III from 242352-240805, Genome Release 64-2-1, reverse complement, Verified ORF, "WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus" [20141208_orf_trans.fasta] TR7098\|c0_g1_i1\|g.4945 ORF TR7098\|c0_g1_i1\|g.4945 TR7098\|c0_g1_i1\|m.4945 type:complete len:516 (+) TR7098\|c0_g1_i1:91-1638(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] TR84\|c0_g1_i1\|g.85 ORF TR84\|c0_g1_i1\|g.85 TR84\|c0_g1_i1\|m.85 type:complete len:516 (+) TR84\|c0_g1_i1:30-1577(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YCR072C SGDID:S000000668, Chr III from 242352-240805, Genome Release 64-1-1, reverse complement, Verified ORF, "WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_9319\|g.6623 ORF asmbl_9319\|g.6623 asmbl_9319\|m.6623 type:complete len:516 (+) asmbl_9319:57-1604(+) [DBVPG6044_Trinity_v2_2_0_PASA_6May2016-contam.fasta] asmbl_9061\|g.6628 ORF asmbl_9061\|g.6628 asmbl_9061\|m.6628 type:complete len:516 (+) asmbl_9061:90-1637(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_9155\|g.5692 ORF ID=asmbl_9155\|g.5692 ID=asmbl_9155\|m.5692 type:complete len:516 (+) ID=asmbl_9155:57-1604(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta] ID=asmbl_9068\|g.5530 ORF ID=asmbl_9068\|g.5530 ID=asmbl_9068\|m.5530 type:complete len:516 (+) ID=asmbl_9068:90-1637(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	515 amino acids
Gene Ontology:
Cellular Component:	nucleolus [IDA] ribosome [IDA]
Biological Process:	ribosome biogenesis [RCA] ribosomal large subunit assembly [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTLIPPPSK KQKKEAQLPR EVAIIPKDLP NVSIKFQALD TGDNVGGALR VPGAISEKQL  60
   61 EELLNQLNGT SDDPVPYTFS CTIQGKKASD PVKTIDITDN LYSSLIKPGY NSTEDQITLL 120
  121 YTPRAVFKVK PVTRSSSAIA GHGSTILCSA FAPHTSSRMV TGAGDNTARI WDCDTQTPMH 180
  181 TLKGHYNWVL CVSWSPDGEV IATGSMDNTI RLWDPKSGQC LGDALRGHSK WITSLSWEPI 240
  241 HLVKPGSKPR LASSSKDGTI KIWDTVSRVC QYTMSGHTNS VSCVKWGGQG LLYSGSHDRT 300
  301 VRVWDINSQG RCINILKSHA HWVNHLSLST DYALRIGAFD HTGKKPSTPE EAQKKALENY 360
  361 EKICKKNGNS EEMMVTASDD YTMFLWNPLK STKPIARMTG HQKLVNHVAF SPDGRYIVSA 420
  421 SFDNSIKLWD GRDGKFISTF RGHVASVYQV AWSSDCRLLV SCSKDTTLKV WDVRTRKLSV 480
  481 DLPGHKDEVY TVDWSVDGKR VCSGGKDKMV RLWTH

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		ARX1 BUD20 IPI1 IPI3 MDN1 MRT4 NOG1 NOG2 NOP7 NSA2 NUG1 RIX1 RLP7 RPL38 RSA4 SDA1 TIF6
View Details	Krogan NJ, et al. (2006)		GCN1 GCN20 RSA4 UTP14 YHL039W
View Details	Gavin AC, et al. (2006)		BUD20 IPI3 NOG1 NOG2 NSA2 NUG1 RIX1 RPF2 RSA4 SDA1
View Details	Gavin AC, et al. (2002)		ARX1 BEM2 BMS1 BRX1 BUD20 CIC1 CLU1 CYR1 CYS4 DBP10 DBP9 DCP2 DRS1 EBP2 ERB1 FPR4 GCN1 HAS1 HDA1 HER1 HIS3 INP2 IPI1 IPI3 KRE33 LHP1 LOC1 LSG1 MAK21 MAK5 MDN1 MIS1 MRT4 NAP1 NIP1 NIP7 NMD3 NOC2 NOC3 NOG1 NOG2 NOP1 NOP12 NOP15 NOP16 NOP2 NOP4 NOP56 NOP7 NSA1 NSA2 NUG1 PRT1 PUF6 REI1 RIX1 RIX7 RLP24 RLP7 RPA135 RPA190 RPF1 RPF2 RPG1 RPP2B RPT6 RRP1 RRP12 RSA3 RSA4 RTR1 SDA1 SEC7 SKI2 SNU13 SPB1 SPB4 SSF1 TIF6 TUB3 URB1 UTP10 UTP20 UTP22 YGL036W YTM1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..111]	PSI-BLAST	105.228787	Groucho/tle1, C-terminal domain
2	View Details	[112..430]	PSI-BLAST	223.917458	beta1-subunit of the signal-transducing G protein heterotrimer
3	View Details	[431..515]	PSI-BLAST	237.457575	Tup1, C-terminal domain

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: RSA4

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: