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Protein Overview: HSM3

General Information:
Name(s) found: HSM3 / YBR272C [SGD]
Description(s) found:
Found 31 descriptions.
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  • Proteasome-interacting protein involved in the assembly of the base subcomplex of the 19S proteasomal regulatory particle (RP); involved in DNA mismatch repair during slow growth; weak similarity to Msh1p; related to human 19S subunit S5b [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 480 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: mismatch repair [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKETNYVE NLLTQLENEL NEDNLPEDIN TLLRKCSLNL VTVVSLPDMD VKPLLATIKR  60
   61 FLTSNVSYDS LNYDYLLDVV DKLVPMADFD DVLEVYSAED LVKALRSEID PLKVAACRVI 120
  121 ENSQPKGLFA TSNIIDILLD ILFDEKVEND KLITAIEKAL ERLSTDELIR RRLFDNNLPY 180
  181 LVSVKGRMET VSFVRLIDFL TIEFQFISGP EFKDIIFCFT KEEILKSVED ILVFIELVNY 240
  241 YTKFLLEIRN QDKYWALRHV KKILPVFAQL FEDTENYPDV RAFSTNCLLQ LFAEVSRIEE 300
  301 DEYSLFKTMD KDSLKIGSEA KLITEWLELI NPQYLVKYHK DVVENYFHVS GYSIGMLRNL 360
  361 SADEECFNAI RNKFSAEIVL RLPYLEQMQV VETLTRYEYT SKFLLNEMPK VMGSLIGDGS 420
  421 AGAIIDLETV HYRNSALRNL LDKGEEKLSV WYEPLLREYS KAVNGKNYST GSETKIADCR 480
  481

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2002) BDF2 CDC55 CKB1 DYN1 ECM5 GLY1 HAT1 HAT2 HHF1, HHF2 HIF1 HSM3 ICL1 IML1 KAP123 KRE33 LIP2 MAC1 MDN1 MIS1 MSB1 NIP1 NMD5 PFK1 PRO1 PRT1 PSD2 PSE1 PSH1 RPA135 RPC40 RPG1 RPN12 RPN3 RPN6 RPN8 RPN9 RPT2 RPT3 RPT5 RPT6 RSC3 SAM1 TEL1 TSC11 USO1 UTP20 VTH2 YFR006W YPR077C
    View Details Ho Y, et al. (2002) HSM3 NAS6 RPN13 RPN14 RPT4 RVB2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen IMD1 HSM3 2 Unpublished Fields Lab Data
    View Screen PRE2 HSM3 2 Unpublished Fields Lab Data
    View Screen SEC17 HSM3 2 Unpublished Fields Lab Data
    View Screen GTS1 HSM3 2 Unpublished Fields Lab Data
    View Screen ROM1 HSM3 2 Unpublished Fields Lab Data
    View Screen THP2 HSM3 2 Unpublished Fields Lab Data
    View Screen PRP40 HSM3 2 Unpublished Fields Lab Data
    View Screen HMG1 HSM3 2 Unpublished Fields Lab Data
    View Screen SOG2 HSM3 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data HSM3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..360] ab initio 7.18 No description for 1qoyA was found.
    2 View Details [361..480] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle