Protein Overview: MRPS5

General Information:
Name(s) found:	MRPS5 / YBR251W [SGD]
Description(s) found: Found 32 descriptions. SHOW ALL	Mitochondrial ribosomal protein of the small subunit [SGD]
Organism:	Saccharomyces cerevisiae
Length:	307 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA] mitochondrial small ribosomal subunit [IDA]
Biological Process:	translation [IDA]
Molecular Function:	structural constituent of ribosome [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKRQLSTSV RYLQHYDESL LSRYYPESLL KSIKLAQQTI PEDTKFRVSR NVEFAPPYLD  60
   61 DFTKIHPFWD YKPGMPHLHA QEENNNFSIF RWDQVQQPLP GEGNILPPGV SLPNDGGRKS 120
  121 KSADVAAGLH KQTGVDPDYI TRKLTMKPLV MKRVSNQTGK GKIASFYALV VVGDKNGMVG 180
  181 LGEGKSREEM SKAIFKAHWD AVRNLKEIPR YENRTIYGDI DFRYHGVKLH LRSAKPGFGL 240
  241 RVNHVIFEIC ECAGIKDLSG KVYKSRNDMN IAKGTIEAFT KAQKTLDEVA LGRGKKLVDV 300
  301 RKVYYSS

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Riffle et al. (2010) (Unpublished Data)		MRP1 MRP13 MRP21 MRP4 MRP51 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS8 MRPS9 NAM9 PET123 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM28 RSM7
View Details	(MIPS) Mewes HW, et al. (2004)		MRP1 MRP10 MRP13 MRP17 MRP2 MRP21 MRP4 MRP51 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS8 MRPS9 NAM9 PET123 PPE1 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM7 VAR1 YMR31
View Details	Krogan NJ, et al. (2006)		CBF1 FYV4 MAM33 MRP1 MRP10 MRP17 MRP21 MRP4 MRP51 MRPL8 MRPS12 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS9 NAM9 NCL1 PET123 RIB4 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM28 RSM7 SVL3 SWS2 YDR124W YJR096W YKL151C YSP1
View Details	Gavin AC, et al. (2006)		EHD3 MRP1 MRP13 MRP17 MRP21 MRP4 MRP51 MRPS16 MRPS17 MRPS18 MRPS28 MRPS5 MRPS8 MRPS9 NAM9 PET123 RSM10 RSM19 RSM22 RSM23 RSM25 RSM27 RSM7
View Details	Gavin AC, et al. (2002)		AAR2 BEM2 BRR1 BUD31 CCM1 CDC33 CEF1 CLF1 CSN12 CUS1 CWC2 CWC22 CWC23 DHH1 DIB1 ECM16 ECM2 EHD3 FYV4 GCN2 GEP3 HSC82 HSH155 HTA1 IMG1 LEA1 LIN1 LSM1 LSM2 LSM4 LSM5 LSM6 LSM7 LUC7 MRP1 MRP10 MRP13 MRP17 MRP21 MRP4 MRP51 MRP7 MRPL28 MRPL3 MRPL35 MRPL38 MRPL4 MRPL8 MRPS16 MRPS17 MRPS18 MRPS28 MRPS5 MRPS8 MRPS9 MSL1 MUD1 NAM9 PAP2 PAT1 PET123 PRP11 PRP18 PRP19 PRP21 PRP24 PRP28 PRP3 PRP31 PRP38 PRP39 PRP4 PRP40 PRP42 PRP43 PRP46 PRP6 PRP8 PRP9 PSD2 PUS7 RIX1 RSE1 RSM10 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM7 RVB2 SLU7 SMB1 SMD1 SMD2 SMD3 SME1 SMX2 SMX3 SNP1 SNT309 SNU114 SNU23 SNU56 SNU66 SNU71 SPP381 SPP382 SRB2 STO1 SYF1 TIF4631 TOS4 UBP10 UTP20 UTP21 UTP22 YML6
View Details	Qiu et al. (2008)		EHD3 IMG1 IMG2 MAM33 MNP1 MRP1 MRP10 MRP13 MRP17 MRP2 MRP21 MRP4 MRP51 MRP7 MRPL13 MRPL15 MRPL16 MRPL17 MRPL19 MRPL20 MRPL22 MRPL23 MRPL25 MRPL28 MRPL31 MRPL32 MRPL33 MRPL36 MRPL39 MRPL49 MRPL50 MRPL6 MRPL8 MRPS12 MRPS16 MRPS17 MRPS18 MRPS28 MRPS35 MRPS5 MRPS8 MRPS9 NAM9 PET123 PPE1 RSM10 RSM18 RSM19 RSM22 RSM23 RSM24 RSM25 RSM26 RSM27 RSM28 RSM7 SWS2 VAR1 YML6 YMR31

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#32 Asynchronous Prep-No Phosphopeptide enrichment	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	RGT2	MRPS5	2	Unpublished Fields Lab Data
View Screen	TRZ1	MRPS5	1	Hazbun TR, et al. (2003)
View Screen	RAD1	MRPS5	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	MRPS5	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..136]	MSA	3.128995	View MSA. No confident structure predictions are available.
2	View Details	[137..307]	PSI-BLAST	204.9794	Ribosomal protein S5, C-terminal domain; Ribosomal S5 protein, N-terminal domain

Functions predicted (by domain):

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
structural constituent of ribosome	6.7575603459566	bayes_pls_golite062009
structural molecule activity	6.24187874355454	bayes_pls_golite062009
RNA binding	3.5405508156591	bayes_pls_golite062009
nucleic acid binding	3.06806242310926	bayes_pls_golite062009
binding	2.86619976447436	bayes_pls_golite062009
DNA binding	1.59400162385296	bayes_pls_golite062009
3'-5'-exoribonuclease activity	1.56111033008721	bayes_pls_golite062009
protein binding	1.43319050998069	bayes_pls_golite062009
transcription regulator activity	1.36103792167395	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	1.35935222635763	bayes_pls_golite062009
exoribonuclease activity	1.31205157616894	bayes_pls_golite062009
3'-5' exonuclease activity	1.10842504252923	bayes_pls_golite062009
double-stranded RNA binding	0.967560318725736	bayes_pls_golite062009
mRNA binding	0.625703291171316	bayes_pls_golite062009
transcription factor activity	0.442070779997034	bayes_pls_golite062009
cytoskeletal protein binding	0.403469167264307	bayes_pls_golite062009
RNA helicase activity	0.222896865667011	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2