Protein Overview: MVD1

General Information:
Name(s) found:	MVD1 / YNR043W [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6324371\|ref\|NP_014441.1\| Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer; Mvd1p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S63374 diphosphomevalonate decarboxylase (EC 4.1.1.33) - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1706682\|sp\|P32377.2\|ERG19_YEAST RecName: Full=Diphosphomevalonate decarboxylase; AltName: Full=Mevalonate pyrophosphate decarboxylase; AltName: Full=Mevalonate-5-diphosphate decarboxylase; Short=MDD [NCBI NR] gi\|1302550\|emb\|CAA96324.1\| MVD1 [Saccharomyces cerevisiae] [NCBI NR] gi\|1292890\|emb\|CAA66158.1\| diphosphomevalonate decarboxylase [Saccharomyces cerevisiae] [NCBI NR] gi\|1235684\|gb\|AAC49252.1\| mevalonate pyrophosphate decarboxylase [NCBI NR] Diphosphomevalonate decarboxylase OS=Saccharomyces cerevisiae GN=ERG19 PE=1 SV=2 [Swiss-Prot] (P32377) Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate pyrophosphate decarboxylase) (Mevalonate-5-diphosphate decarboxylase) (MDD) [Swiss-Prot] MVD1 Mevalonate pyrophosphate decarboxylase [mips] Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer [SGD] (P32377) Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate pyrophosphate decarboxylase) [4932.FASTACCERV.txt] Chr XIV from 701892-703082 [hmr_yeast5_DM3-1_pombe.fasta] MVD1, Chr XIV from 701892-703082 [yeast_orfs2] MVD1 SGDID:S0005326, Chr XIV from 701894-703084, Verified ORF [yeastflysequest.fasta] MVD1 SGDID:S0005326, Chr XIV from 701895-703085, Verified ORF [10112005cervSGD.fasta] Mvd1p [Saccharomyces cerevisiae]gi\|1292890\|emb\|CAA66158.1\| diphosphomevalonate decarboxylase [Saccharomyces cerevisiae]gi\|1302550\|emb\|CAA96324.1\| MVD1 [Saccharomyces cerevisiae]gi\|1235684\|gb\|AAC49252.1\| mevalonate pyrophosphate decarboxylasegi\|2131230 [nrdb_11152004_Chlamydomonas] MVD1 SGDID:S000005326, Chr XIV from 701897-703087, Verified ORF, "Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer; Mvd1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Diphosphomevalonate decarboxylase (Mevalonate pyrophosphate decarboxylase) (Mevalonate-5-diphosphate decarboxylase) (MDD) [nr-271106-contam.fasta] diphosphomevalonate decarboxylase [Saccharomyces cerevisiae] [nr-271106-contam.fasta] MVD1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] mevalonate pyrophosphate decarboxylase [nr-271106-contam.fasta] MVD1 SGDID:S000005326, Chr XIV from 701898-703088, Verified ORF, "Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer" [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta] [chemostatdb.fasta] MVD1 SGDID:S000005326, Chr XIV from 701895-703085, Genome Release 64-1-1, Verified ORF, "Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer" [yeast-030211-contam.fasta] MVD1 SGDID:S000005326, Chr XIV from 701895-703085, Genome Release 64-2-1, Verified ORF, "Mevalonate pyrophosphate decarboxylase; essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer" [20141208_orf_trans.fasta] YNR043W SGDID:S000005326, Chr XIV from 701895-703085, Genome Release 64-1-1, Verified ORF, "Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	396 amino acids
Gene Ontology:
Cellular Component:	cytosol [TAS]
Biological Process:	ergosterol biosynthetic process [TAS] isoprenoid biosynthetic process [TAS]
Molecular Function:	diphosphomevalonate decarboxylase activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVYTASVTA PVNIATLKYW GKRDTKLNLP TNSSISVTLS QDDLRTLTSA ATAPEFERDT  60
   61 LWLNGEPHSI DNERTQNCLR DLRQLRKEME SKDASLPTLS QWKLHIVSEN NFPTAAGLAS 120
  121 SAAGFAALVS AIAKLYQLPQ STSEISRIAR KGSGSACRSL FGGYVAWEMG KAEDGHDSMA 180
  181 VQIADSSDWP QMKACVLVVS DIKKDVSSTQ GMQLTVATSE LFKERIEHVV PKRFEVMRKA 240
  241 IVEKDFATFA KETMMDSNSF HATCLDSFPP IFYMNDTSKR IISWCHTINQ FYGETIVAYT 300
  301 FDAGPNAVLY YLAENESKLF AFIYKLFGSV PGWDKKFTTE QLEAFNHQFE SSNFTARELD 360
  361 LELQKDVARV ILTQVGSGPQ ETNESLIDAK TGLPKE

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		MVD1 SGT1 YPL191C
View Details	Gavin AC, et al. (2006)		BMS1 BUD21 DBP8 ENP2 ESF1 HCA4 KRR1 MVD1 NOP56 NOP6 RPL26B
View Details	Gavin AC, et al. (2002)		ADE4 ASC1 BFR2 BMS1 BRX1 BUD21 CBF5 CFT2 CKA1 CKA2 CKB1 CKB2 CMS1 DBP8 DIA4 DIM1 DIP2 DIS3 ECM16 ECM29 EMG1 ENP1 ENP2 ERO1 ESF1 ESF2 FAP7 FIP1 GCN1 GLC7 HAS1 HCA4 HHF1, HHF2 HSL1 HTA2 IMP3 IMP4 KRE33 KRR1 LCP5 LTV1 MPP10 MRD1 MVD1 NAN1 NOB1 NOC2 NOC4 NOP1 NOP12 NOP14 NOP56 NOP58 NOP6 PAP1 PFS2 PNO1 PRE6 PRE9 PRP43 PTA1 PTI1 PWP2 RCL1 REF2 RML2 RNA14 ROK1 RPP2B RRP12 RRP7 RRP9 RTG2 SAM1 SCL1 SEC21 SLX9 SOF1 SRO9 TIF1, TIF2 TSR1 UTP10 UTP11 UTP13 UTP15 UTP18 UTP20 UTP21 UTP22 UTP30 UTP4 UTP6 UTP7 UTP8 UTP9 YOR059C YSH1