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Catalysis of the reaction: ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2. Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound. Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: diphosphomevalonate decarboxylase activity
Acc: GO:0004163
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2.
Synonyms:
  • mevalonate-5-pyrophosphate decarboxylase activity
  • 5-pyrophosphomevalonate decarboxylase activity
  • mevalonate diphosphate decarboxylase activity
  • pyrophosphomevalonic acid decarboxylase activity
  • pyrophosphomevalonate decarboxylase activity
  • ATP:(R)-5-diphosphomevalonate carboxy-lyase (adding ATP; isopentenyl-diphosphate-forming)
  • ATP:(R)-5-diphosphomevalonate carboxy-lyase (dehydrating)
  • mevalonate pyrophosphate decarboxylase activity
  • mevalonate 5-diphosphate decarboxylase activity
Proteins in PDR annotated with:
   This term: 14 [Search]
   Term or descendants: 14 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004163 - diphosphomevalonate decarboxylase activity (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle