YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: RSC6

General Information:
Name(s) found: RSC6 / YCR052W [SGD]
Description(s) found:
Found 26 descriptions.
SHOW ALL
  • Component of the RSC chromatin remodeling complex; essential for mitotic growth; homolog of SWI/SNF subunit Swp73p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 483 amino acids

    Gene Ontology:
    Cellular Component: RSC complex [IDALink to PubMed articleLink to PubMed article][IPILink to PubMed article]
    Biological Process: ATP-dependent chromatin remodeling [IDALink to PubMed article]
    Molecular Function: DNA-dependent ATPase activity [IDALink to PubMed articleLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTQTNPVPV TYPTDAYIPT YLPDDKVSNL ADLKKLIEMD SRLDLYLTRR RLDTSINLPT  60
   61 NTKTKDHPPN KEMLRIYVYN TTESSPRSDS GTPADSGKTT WTLRIEGKLL HESANGKHPF 120
  121 SEFLEGVAVD FKRLKPLGMG KKRKRDSSLS LPLNLQQPEY NDQDSTMGDN DNGEDEDSAE 180
  181 AESREEIVDA LEWNYDENNV VEFDGIDIKR QGKDNLRCSI TIQLRGVDGG KVQYSPNLAT 240
  241 LIGMQTGSVN DAVYSIYKYI LINNLFVTEQ TEAQDGSNDA EDSSNENNNK NGAGDDDGVE 300
  301 GSTPKDKPEL GEVKLDSLLQ KVLDTNAAHL PLMNVVQTVN KLVSPLPPII LDYTIDLSKD 360
  361 TTYGATTLDV DVSHILHQPQ PQPNLQKEEE TDAEDTAKLR EITKLALQLN SSAQKYQFFH 420
  421 ELSLHPRETL THYLWSSKQN ELVLQGDQYF NEDAARTSDI YSNNNNDRSL MGNISLLYSQ 480
  481 GRL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ARP7 ARP9 HTL1 NFI1 NPL6 RSC1 RSC2 RSC3 RSC30 RSC4 RSC58 RSC6 RSC8 RSC9 RTT102 SFH1 STH1 VPS1
    View Details (MIPS) Mewes HW, et al. (2004) ARP7 ARP9 RSC1 RSC2 RSC4 RSC6 RSC8 SAS5 SFH1 STH1
    View Details Krogan NJ, et al. (2006) ARP7 ARP9 ATG16 CSH1 GRS2 HTL1 MGR1 NFI1 NPL6 PCL9 RIM15 RSC1 RSC2 RSC3 RSC4 RSC58 RSC6 RSC8 RSC9 RTT102 SFH1 STH1 URC2 YIL177C
    View Details Gavin AC, et al. (2006) ARP7 NPL6 RSC1 RSC2 RSC3 RSC4 RSC58 RSC6 RSC8 RSC9 SFH1 STH1
    View Details Gavin AC, et al. (2002) ACT1 ADH1 ARP4 ARP8 ESC8 GCN1 IES1 IES5 INO80 IOC3 ISW1 ISW2 ITC1 MOT1 NHP10 NPL6 PDC1 RPC40 RSC2 RSC4 RSC58 RSC6 RSC8 RVB2 SIN3 SPT15 VPS1
    View Details Qiu et al. (2008) ARP7 ARP9 NPL6 RSC1 RSC2 RSC4 RSC6 RSC8 SFH1 STH1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MIH1 control 1 McCusker D, et al (2007)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..266] MSA 1.013955 View MSA. No confident structure predictions are available.
    2 View Details [267..326] deduced N/A No confident structure predictions are available.
    3 View Details [327..483] MSA 1.017969 View MSA. No confident structure predictions are available.
    4 View Details [214..378] PSI-BLAST 29.69897 Solution structure of the SWIB domain of mouse BRG1-associated factor 60a
    5 View Details [379..483] MSA 2.041995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transcription regulator activity
    		•  4.01592136607858 bayes_pls_golite062009
  • basal transcription repressor activity
    		•  3.09418413549897 bayes_pls_golite062009
  • binding
    		•  2.67987108623459 bayes_pls_golite062009
  • transcription coactivator activity
    		•  2.58234407051051 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  2.32480271621458 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.98538788872171 bayes_pls_golite062009
  • transcription activator activity
    		•  1.83085389017135 bayes_pls_golite062009
  • transcription factor binding
    		•  1.73032563380905 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.60414428986898 bayes_pls_golite062009
  • protein binding
    		•  1.58138506346812 bayes_pls_golite062009
  • structural molecule activity
    		•  1.28917299936669 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  1.06026105710513 bayes_pls_golite062009
  • catalytic activity
    		•  0.121624777548864 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle