YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: REX2

General Information:
Name(s) found: REX2 / YLR059C [SGD]
Description(s) found:
Found 30 descriptions.
SHOW ALL
  • 3'-5' RNA exonuclease; involved in 3'-end processing of U4 and U5 snRNAs, 5S and 5.8S rRNAs, and RNase P and RNase MRP RNA; localized to mitochondria and null suppresses escape of mtDNA to nucleus in yme1 yme2 mutants; RNase D exonuclease [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 269 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed articleLink to PubMed article][IMPLink to PubMed article]
    Biological Process: RNA processing [IMPLink to PubMed article]
    Molecular Function: 3'-5' exonuclease activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKWLLFPARI VARTRPNLFS LYRRSVSQYL RPRTIQNLQS MAQTPELKTK LFKPLVWIDC  60
   61 EMTGLDHVND RIIEICCIIT DGHLAPVKAA DGQGDSHYES VIHYGPEVMN KMNEWCIEHH 120
  121 GNSGLTAKVL ASEKTLAQVE DELLEYIQRY IPDKNVGVLA GNSVHMDRLF MVREFPKVID 180
  181 HLFYRIVDVS SIMEVARRHN PALQARNPKK EAAHTAYSDI KESIAQLQWY MDNYLKPPQE 240
  241 TESVESIGSE QPESPSSSTS SLKRQRTDF

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) AAC1 AAC3 ADE5,7 ADK1 AHA1 AIP1 ARC1 ARO1 ARO9 ARP2 ATG11 ATG12 ATG17 CAR2 CLU1 COF1 COP1 CPA2 CPR6 CYR1 DUN1 FET4 GCD11 GCN1 GFA1 GPH1 GUS1 IPP1 KAP114 MMS2 MRE11 NAN1 PHO81 PPX1 PRB1 PRP11 PTC7 RAD18 RAD50 REP1 REX2 RPN10 RPN11 RPN3 RPN5 RPN6 RPN7 RPT1 RPT3 SEC18 SEC27 SHM2 SRV2 SSK2 TCB1 TFP1 THI22 TIF1, TIF2 TIF4631 TOS3 TYR1 UBA1 UBC13 UBP15 UTP13 XRS2 YGR250C YHR020W YHR033W YNL208W

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SPT21 REX2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data REX2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..269] PSI-BLAST 24.522879 Exonuclease I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonuclease activity
    		•  4.81599779544001 bayes_pls_golite062009
  • exoribonuclease activity
    		•  3.01417328311605 bayes_pls_golite062009
  • ribonuclease H activity
    		•  2.91966688044755 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  2.89077854960958 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  2.70794511869438 bayes_pls_golite062009
  • nuclease activity
    		•  2.65398446409354 bayes_pls_golite062009
  • endonuclease activity
    		•  2.63074055051349 bayes_pls_golite062009
  • endoribonuclease activity
    		•  2.59247838057313 bayes_pls_golite062009
  • hydrolase activity
    		•  2.41899414621161 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.20855917457806 bayes_pls_golite062009
  • endoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.74431545836806 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.73824903971928 bayes_pls_golite062009
  • DNA binding
    		•  1.62101283948059 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.59628511603826 bayes_pls_golite062009
  • exonuclease activity
    		•  1.4327316829508 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  1.42069917818896 bayes_pls_golite062009
  • binding
    		•  1.35497934205068 bayes_pls_golite062009
  • catalytic activity
    		•  1.25233849524628 bayes_pls_golite062009
    		• 1.18236432793831 bayes_pls_golite062009
  • transcription factor activity
    		•  0.971926865662649 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.86862629020506 bayes_pls_golite062009
  • RNA binding
    		•  0.750194803368593 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.389326716045122 bayes_pls_golite062009
  • transcription activator activity
    		•  0.104967281174106 bayes_pls_golite062009
  • protein binding
    		•  0.035326007863533 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle