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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ASC1
  • cytoplasm
  • telomere maintenance
  • negative regulation of translation
  • molecular_function
  • CLU1
  • cytoplasm
  • eukaryotic translation initiation factor 3 complex
  • translational initiation
  • mitochondrion organization
  • molecular_function
  • ECM29
  • nucleus
  • cytoplasm
  • proteasome complex
  • protein catabolic process
  • protein binding
  • GCN1
  • mitochondrion
  • cytosol
  • regulation of translational elongation
  • molecular_function
  • GCN20
  • cytosol
  • regulation of translational elongation
  • ATPase activity
  • MET18
  • nucleoplasm
  • telomere maintenance
  • nucleotide-excision repair
  • transcription from RNA polymerase II promoter
  • methionine metabolic process
  • RNA polymerase II transcription factor activity
  • RAD3
  • holo TFIIH complex
  • nucleotide-excision repair factor 3 complex
  • negative regulation of transcription from RNA polymerase II promoter, mitotic
  • nucleotide-excision repair, DNA duplex unwinding
  • nucleotide-excision repair
  • transcription initiation from RNA polymerase II promoter
  • DNA helicase activity
  • general RNA polymerase II transcription factor activity
  • RPN10
  • proteasome regulatory particle, base subcomplex
  • proteasome complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • RPT3
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • RPT6
  • nucleus
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • TFP1
  • vacuolar proton-transporting V-type ATPase, V1 domain
  • fungal-type vacuole membrane
  • protein metabolic process
  • vacuolar acidification
  • intron homing
  • proton-transporting ATPase activity, rotational mechanism
  • endodeoxyribonuclease activity
  • TUB3
  • tubulin complex
  • kinetochore microtubule
  • spindle pole body
  • polar microtubule
  • nuclear microtubule
  • cytoplasmic microtubule
  • homologous chromosome segregation
  • mitotic sister chromatid segregation
  • nuclear migration along microtubule
  • nuclear migration during conjugation with cellular fusion
  • structural constituent of cytoskeleton
  • YDJ1
  • perinuclear region of cytoplasm
  • microsome
  • cytosol
  • protein targeting to mitochondrion
  • response to drug
  • protein targeting to ER
  • ER-associated protein catabolic process
  • protein refolding
  • 'de novo' protein folding
  • Hsp70/Hsc70 protein regulator activity
  • unfolded protein binding
  • chaperone regulator activity
  • ATPase activator activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    proteasome regulatory particle, base subcomplex 5.7481E-7 13 9 3 6292
    proteasome complex 2.0274E-6 13 48 4 6292
    proteasome regulatory particle 1.1918E-5 13 23 3 6292
    proteasome accessory complex 1.1918E-5 13 23 3 6292
    protein complex 6.0345E-4 13 1137 8 6292
    perinuclear region of cytoplasm 4.1283E-3 13 2 1 6292
    tubulin complex 6.1865E-3 13 3 1 6292
    polar microtubule 6.1865E-3 13 3 1 6292
    macromolecular complex 7.225E-3 13 1635 8 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein metabolic process 5.9807E-6 13 1136 10 6292
    protein catabolic process 2.4539E-5 13 189 5 6292
    macromolecule metabolic process 6.1467E-5 13 2349 12 6292
    regulation of translation 1.8907E-4 13 57 3 6292
    macromolecule catabolic process 2.0324E-4 13 294 5 6292
    modification-dependent protein catabolic process 2.1833E-4 13 156 4 6292
    ubiquitin-dependent protein catabolic process 2.1833E-4 13 156 4 6292
    posttranscriptional regulation of gene expression 2.3144E-4 13 61 3 6292
    proteolysis involved in cellular protein catabolic process 2.3497E-4 13 159 4 6292
    modification-dependent macromolecule catabolic process 2.6472E-4 13 164 4 6292
    regulation of translational elongation 3.0349E-4 13 13 2 6292
    cellular protein catabolic process 3.1084E-4 13 171 4 6292
    regulation of cellular protein metabolic process 3.1959E-4 13 68 3 6292
    cellular protein metabolic process 4.0236E-4 13 1074 8 6292
    regulation of protein metabolic process 4.1043E-4 13 74 3 6292
    proteolysis 4.4667E-4 13 188 4 6292
    cellular macromolecule metabolic process 4.9766E-4 13 2285 11 6292
    primary metabolic process 6.6865E-4 13 2896 12 6292
    translational elongation 1.5505E-3 13 29 2 6292
    cellular macromolecule catabolic process 1.627E-3 13 265 4 6292
    metabolic process 1.7612E-3 13 3157 12 6292
    catabolic process 2.253E-3 13 496 5 6292
    nucleotide-excision repair 2.6567E-3 13 38 2 6292
    translation 5.8264E-3 13 376 4 6292
    cellular metabolic process 7.9165E-3 13 3033 11 6292
    cellular catabolic process 8.2693E-3 13 415 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    endopeptidase activity 1.6085E-4 13 54 3 6292
    nucleoside-triphosphatase activity 3.4449E-4 13 329 5 6292
    hydrolase activity, acting on acid anhydrides 4.781E-4 13 353 5 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4.781E-4 13 353 5 6292
    pyrophosphatase activity 4.781E-4 13 353 5 6292
    ATPase activity 6.9245E-4 13 211 4 6292
    peptidase activity, acting on L-amino acid peptides 8.546E-4 13 95 3 6292
    Hsp70/Hsc70 protein regulator activity 4.1283E-3 13 2 1 6292
    hydrolase activity 6.2534E-3 13 911 6 6292
    peptidase activity 6.3817E-3 13 192 3 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle