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Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation. Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: kinetochore microtubule
Acc: GO:0005828
Aspect: Cellular Component
Desc: Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation.
Synonyms:
  • pole-to-kinetochore microtubule
Proteins in PDR annotated with:
   This term: 31 [Search]
   Term or descendants: 31 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0005828 - kinetochore microtubule (interactive image map)

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