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The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells. The proteolytic degradation of proteins in the cytosol that contributes to apoptosis. The chemical reactions and pathways resulting in the breakdown of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin; especially, the proteolytic cleavage of hemoglobin to yield free heme, peptides, and amino acids. The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation. The chemical reactions and pathways resulting in the breakdown of mannoproteins, any protein that contains covalently bound mannose residues other than as a moiety of nucleic acid. The proteolytic degradation of cytoskeletal proteins that contributes to apoptosis, leading to the collapse of cytoskeletal structures. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. The proteolytic digestion of components in the acrosomal matrix that allows for their release into the egg. The dispersal of the components allows for the inner acrosomal membrane to interact with the egg. The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein. The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with the hydrolysis of peptide bonds. The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins. The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes protein modification. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: proteolysis involved in cellular protein catabolic process
Acc: GO:0051603
Aspect: Biological Process
Desc: The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
Synonyms:
  • peptidolysis during cellular protein catabolic process
  • proteolysis during cellular protein catabolism
  • peptidolysis involved in cellular protein catabolic process
  • peptidolysis involved in cellular protein catabolism
  • proteolysis during cellular protein catabolic process
  • peptidolysis during cellular protein catabolism
Proteins in PDR annotated with:
   This term: 97 [Search]
   Term or descendants: 1517 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051603 - proteolysis involved in cellular protein catabolic process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle