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The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin moiety, or multiple ubiquitin moieties, to the protein. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein SMT3 to the target protein. The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein. The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein. The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with the hydrolysis of peptide bonds. The chemical reactions and pathways resulting in the breakdown of prenylated proteins. The chemical reactions and pathways resulting in the breakdown of a protein by individual cells. The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: modification-dependent protein catabolic process
Acc: GO:0019941
Aspect: Biological Process
Desc: The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.
Synonyms:
  • protein degradation tagging activity
  • protein-ligand-dependent protein catabolism
  • modification-dependent protein catabolism
  • protein-ligand-dependent protein catabolic process
  • modification-dependent protein breakdown
  • modification-initiated proteolysis
  • modification-initiated protein catabolism
  • modification-dependent proteolysis
  • modification-dependent protein degradation
  • modification-initiated protein catabolic process
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 1382 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0019941 - modification-dependent protein catabolic process (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle