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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AVO1
  • TORC2 complex
  • cytoplasm
  • fungal-type cell wall organization
  • negative regulation of Ras protein signal transduction
  • regulation of cell growth
  • establishment or maintenance of actin cytoskeleton polarity
  • Ras GTPase binding
  • BEM2
  • mitochondrion
  • intracellular
  • small GTPase mediated signal transduction
  • cellular cell wall organization
  • microtubule cytoskeleton organization
  • budding cell bud growth
  • actin cytoskeleton organization
  • Rho GTPase activator activity
  • signal transducer activity
  • CEG1
  • nucleus
  • mRNA capping
  • positive regulation of transcription from RNA polymerase II promoter
  • mRNA guanylyltransferase activity
  • CET1
  • nucleus
  • mRNA capping
  • polynucleotide 5'-phosphatase activity
  • CLU1
  • cytoplasm
  • eukaryotic translation initiation factor 3 complex
  • translational initiation
  • mitochondrion organization
  • molecular_function
  • CTR9
  • nucleus
  • transcription elongation factor complex
  • Cdc73/Paf1 complex
  • histone methylation
  • transcription from RNA polymerase II promoter
  • chromosome segregation
  • RNA elongation from RNA polymerase II promoter
  • RNA polymerase II transcription elongation factor activity
  • triplex DNA binding
  • HHF1, HHF2
  • nucleus
  • nucleoplasm part
  • nuclear nucleosome
  • chromosome
  • replication fork protection complex
  • chromatin remodeling complex
  • nucleosome
  • histone acetyltransferase complex
  • nucleoplasm
  • histone H3-K79 methylation
  • DNA repair
  • negative regulation of transcription
  • chromatin assembly or disassembly
  • positive regulation of transcription
  • nucleosome assembly
  • DNA binding
  • LSM12
  • nucleus
  • cytoplasm
  • ribosome
  • RNA metabolic process
  • RNA binding
  • NIP1
  • multi-eIF complex
  • cytoplasm
  • eukaryotic translation initiation factor 3 complex
  • ribosome biogenesis
  • translational initiation
  • translation initiation factor activity
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • PDB1
  • mitochondrial pyruvate dehydrogenase complex
  • mitochondrion
  • mitochondrial nucleoid
  • pyruvate metabolic process
  • pyruvate dehydrogenase (acetyl-transferring) activity
  • PRP43
  • mitochondrion
  • spliceosomal complex
  • nuclear outer membrane
  • maturation of SSU-rRNA
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • rRNA processing
  • processing of 27S pre-rRNA
  • ATP-dependent RNA helicase activity
  • RPG1
  • incipient cellular bud site
  • cytoplasm
  • ribosome
  • eukaryotic translation initiation factor 3 complex
  • translational initiation
  • translation initiation factor activity
  • SPT16
  • FACT complex
  • nuclear chromatin
  • alpha DNA polymerase:primase complex
  • transcription elongation factor complex
  • transcription initiation from RNA polymerase II promoter
  • RNA elongation from RNA polymerase II promoter
  • transcription elongation regulator activity
  • RNA polymerase II transcription elongation factor activity
  • SSA3
  • cytosol
  • SRP-dependent cotranslational protein targeting to membrane, translocation
  • protein folding
  • response to stress
  • ATPase activity
  • unfolded protein binding
  • SSA4
  • nucleus
  • cytoplasm
  • SRP-dependent cotranslational protein targeting to membrane, translocation
  • protein folding
  • response to stress
  • ATPase activity
  • unfolded protein binding
  • TOP2
  • nucleus
  • mitochondrion
  • synaptonemal complex
  • reciprocal meiotic recombination
  • DNA strand elongation involved in DNA replication
  • regulation of mitotic recombination
  • chromatin assembly or disassembly
  • DNA topological change
  • DNA topoisomerase (ATP-hydrolyzing) activity
  • VPS1
  • membrane fraction
  • peroxisome
  • cytoplasm
  • mitochondrial outer membrane
  • protein retention in Golgi apparatus
  • peroxisome organization
  • vacuolar transport
  • protein targeting to vacuole
  • actin cytoskeleton organization
  • GTPase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    eukaryotic translation initiation factor 3 complex 6.8335E-7 18 7 3 6292
    nuclear replication fork 1.4247E-3 18 20 2 6292
    macromolecular complex 1.7287E-3 18 1635 11 6292
    transcription elongation factor complex 1.8874E-3 18 23 2 6292
    FACT complex 5.7138E-3 18 2 1 6292
    replication fork protection complex 5.7138E-3 18 2 1 6292
    replication fork 6.2199E-3 18 42 2 6292
    protein complex 8.7384E-3 18 1137 8 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mRNA capping 2.3152E-5 18 3 2 6292
    RNA capping 4.6226E-5 18 4 2 6292
    translational initiation 2.1052E-4 18 42 3 6292
    macromolecule methylation 2.259E-4 18 43 3 6292
    methylation 2.259E-4 18 43 3 6292
    cellular macromolecule metabolic process 4.0124E-4 18 2285 14 6292
    SRP-dependent cotranslational protein targeting to membrane, translocation 4.1874E-4 18 11 2 6292
    one-carbon metabolic process 4.7003E-4 18 55 3 6292
    macromolecule metabolic process 5.5843E-4 18 2349 14 6292
    gene expression 1.0495E-3 18 1283 10 6292
    histone methylation 1.4247E-3 18 20 2 6292
    SRP-dependent cotranslational protein targeting to membrane 1.572E-3 18 21 2 6292
    cellular process 1.7601E-3 18 4426 18 6292
    protein amino acid alkylation 2.0555E-3 18 24 2 6292
    cotranslational protein targeting to membrane 2.0555E-3 18 24 2 6292
    protein amino acid methylation 2.0555E-3 18 24 2 6292
    cellular metabolic process 2.3595E-3 18 3033 15 6292
    histone H3-K79 methylation 2.8608E-3 18 1 1 6292
    actin cytoskeleton organization 3.7809E-3 18 113 3 6292
    protein targeting to ER 3.8728E-3 18 33 2 6292
    metabolic process 3.8933E-3 18 3157 15 6292
    actin filament-based process 4.1707E-3 18 117 3 6292
    chromatin assembly or disassembly 4.3495E-3 18 35 2 6292
    RNA elongation from RNA polymerase II promoter 5.3803E-3 18 39 2 6292
    protein localization in endoplasmic reticulum 5.6539E-3 18 40 2 6292
    histone lysine methylation 5.7138E-3 18 2 1 6292
    intracellular protein transmembrane transport 6.2199E-3 18 42 2 6292
    primary metabolic process 6.241E-3 18 2896 14 6292
    RNA elongation 7.1157E-3 18 45 2 6292
    protein localization in organelle 8.1798E-3 18 149 3 6292
    organelle organization 8.2746E-3 18 1127 8 6292
    protein targeting to membrane 9.4186E-3 18 52 2 6292
    nucleic acid metabolic process 9.4905E-3 18 1415 9 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RNA polymerase II transcription elongation factor activity 5.9184E-4 18 13 2 6292
    transcription elongation regulator activity 1.2844E-3 18 19 2 6292
    translation initiation factor activity 2.6008E-3 18 27 2 6292
    triplex DNA binding 2.8608E-3 18 1 1 6292
    mRNA guanylyltransferase activity 2.8608E-3 18 1 1 6292
    DNA topoisomerase (ATP-hydrolyzing) activity 2.8608E-3 18 1 1 6292
    binding 5.1118E-3 18 1294 9 6292
    RNA guanylyltransferase activity 5.7138E-3 18 2 1 6292
    polynucleotide 5'-phosphatase activity 5.7138E-3 18 2 1 6292
    translation factor activity, nucleic acid binding 6.8109E-3 18 44 2 6292
    nucleic acid binding 8.3629E-3 18 666 6 6292
    nucleotide phosphatase activity 8.5592E-3 18 3 1 6292
    guanylyltransferase activity 8.5592E-3 18 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle