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The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine). The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative. The addition of a methyl group to a glutamic acid residue in a protein. The addition of a methyl group to a glutamine residue in a protein. The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. The modification of histones by addition of methyl groups. The addition of a methyl group to an arginine residue in a protein. The process by which a methyl group is covalently attached to a molecule. The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine. The methylation of the N-terminal amino acid of a protein. The methylation of the C-terminal amino acid of a protein. The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom. The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule. The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. The addition of an alkyl group to a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom. The covalent alteration of one or more amino acids occurring in a protein after the protein has been completely translated and released from the ribosome.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: protein amino acid methylation
Acc: GO:0006479
Aspect: Biological Process
Desc: The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
Proteins in PDR annotated with:
   This term: 58 [Search]
   Term or descendants: 272 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0006479 - protein amino acid methylation (interactive image map)

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