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View Protein Complex Details

Complex Overview

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ADA2
  • SLIK (SAGA-like) complex
  • Ada2/Gcn5/Ada3 transcription activator complex
  • SAGA complex
  • chromatin modification
  • histone acetylation
  • transcription coactivator activity
  • GCN5
  • SLIK (SAGA-like) complex
  • Ada2/Gcn5/Ada3 transcription activator complex
  • SAGA complex
  • chromatin modification
  • histone acetylation
  • histone acetyltransferase activity
  • transcription coactivator activity
  • HEM13
  • mitochondrial inner membrane
  • heme biosynthetic process
  • coproporphyrinogen oxidase activity
  • HFI1
  • SLIK (SAGA-like) complex
  • Ada2/Gcn5/Ada3 transcription activator complex
  • SAGA complex
  • chromatin modification
  • telomere maintenance
  • transcription from RNA polymerase II promoter
  • histone acetylation
  • transcription cofactor activity
  • transcription coactivator activity
  • MES1
  • cytoplasm
  • methionyl glutamyl tRNA synthetase complex
  • methionyl-tRNA aminoacylation
  • methionine-tRNA ligase activity
  • MYO4
  • cellular bud
  • mitochondrion
  • myosin V complex
  • filamentous actin
  • intracellular mRNA localization
  • endoplasmic reticulum inheritance
  • gene conversion at mating-type locus
  • actin filament binding
  • microfilament motor activity
  • NGG1
  • SLIK (SAGA-like) complex
  • Ada2/Gcn5/Ada3 transcription activator complex
  • SAGA complex
  • chromatin modification
  • response to drug
  • histone acetylation
  • transcription cofactor activity
  • PSK1
  • cytoplasm
  • hexose metabolic process
  • protein amino acid phosphorylation
  • protein serine/threonine kinase activity
  • PTC1
  • nucleus
  • cytoplasm
  • mitochondrion inheritance
  • inactivation of MAPK activity involved in osmosensory signaling pathway
  • protein amino acid dephosphorylation
  • telomere maintenance
  • tRNA splicing, via endonucleolytic cleavage and ligation
  • protein serine/threonine phosphatase activity
  • phosphoprotein phosphatase activity
  • metal ion binding
  • catalytic activity
  • hydrolase activity
  • RPB2
  • mitochondrion
  • DNA-directed RNA polymerase II, core complex
  • transcription from RNA polymerase II promoter
  • DNA-directed RNA polymerase activity
  • RPO21
  • mitochondrion
  • DNA-directed RNA polymerase II, core complex
  • transcription from RNA polymerase II promoter
  • DNA-directed RNA polymerase activity
  • SGF29
  • SAGA complex
  • histone acetylation
  • molecular_function
  • SGF73
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • histone acetylation
  • histone acetyltransferase activity
  • structural molecule activity
  • SPT20
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • histone acetylation
  • transcription cofactor activity
  • SPT7
  • SLIK (SAGA-like) complex
  • mitochondrion
  • SAGA complex
  • chromatin modification
  • protein complex assembly
  • conjugation with cellular fusion
  • histone acetylation
  • structural molecule activity
  • SPT8
  • nucleus
  • SAGA complex
  • negative regulation of transcription from RNA polymerase II promoter
  • positive regulation of transcription from RNA polymerase II promoter
  • transcription cofactor activity
  • TATA-binding protein binding
  • TAF1
  • transcription factor TFIID complex
  • protein amino acid phosphorylation
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • histone acetyltransferase activity
  • general RNA polymerase II transcription factor activity
  • protein serine/threonine kinase activity
  • TAF10
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF11
  • transcription factor TFIID complex
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF12
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF3
  • transcription factor TFIID complex
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF5
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF6
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF7
  • nucleus
  • transcription factor TFIID complex
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • TAF9
  • transcription factor TFIID complex
  • SLIK (SAGA-like) complex
  • SAGA complex
  • chromatin modification
  • protein amino acid acetylation
  • histone acetylation
  • chromatin organization
  • regulation of transcription involved in G1 phase of mitotic cell cycle
  • transcription initiation from RNA polymerase II promoter
  • general RNA polymerase II transcription factor activity
  • UBP8
  • SAGA complex
  • protein deubiquitination
  • ubiquitin-specific protease activity
  • VAS1
  • cytoplasm
  • mitochondrion
  • valyl-tRNA aminoacylation
  • valine-tRNA ligase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    SAGA complex 4.0593E-33 27 22 15 6292
    SAGA-type complex 1.1649E-32 27 23 15 6292
    SLIK (SAGA-like) complex 3.9429E-27 27 16 12 6292
    histone acetyltransferase complex 5.2601E-27 27 44 15 6292
    nucleoplasm part 2.5718E-25 27 245 21 6292
    nucleoplasm 1.294E-24 27 264 21 6292
    nuclear lumen 1.2813E-19 27 453 21 6292
    transcription factor TFIID complex 5.4539E-19 27 15 9 6292
    DNA-directed RNA polymerase II, holoenzyme 1.1497E-16 27 56 11 6292
    organelle lumen 3.2768E-16 27 660 21 6292
    intracellular organelle lumen 3.2768E-16 27 660 21 6292
    membrane-enclosed lumen 1.1029E-15 27 700 21 6292
    protein complex 5.6316E-14 27 1137 23 6292
    transcription factor complex 7.0188E-12 27 71 9 6292
    nuclear part 1.1312E-11 27 1103 21 6292
    macromolecular complex 1.7454E-10 27 1635 23 6292
    Ada2/Gcn5/Ada3 transcription activator complex 1.3411E-9 27 5 4 6292
    nucleus 2.0834E-7 27 2041 22 6292
    intracellular organelle part 2.2271E-7 27 2282 23 6292
    organelle part 2.2271E-7 27 2282 23 6292
    membrane-bounded organelle 1.7041E-4 27 3771 25 6292
    intracellular membrane-bounded organelle 1.7041E-4 27 3771 25 6292
    intracellular organelle 9.2018E-4 27 4070 25 6292
    organelle 9.2512E-4 27 4071 25 6292
    DNA-directed RNA polymerase II, core complex 1.1399E-3 27 12 2 6292
    intracellular part 1.4188E-3 27 4938 27 6292
    intracellular 1.7365E-3 27 4975 27 6292
    DNA-directed RNA polymerase complex 7.6378E-3 27 31 2 6292
    RNA polymerase complex 7.6378E-3 27 31 2 6292
    nuclear DNA-directed RNA polymerase complex 7.6378E-3 27 31 2 6292
    myosin V complex 8.5646E-3 27 2 1 6292
    filamentous actin 8.5646E-3 27 2 1 6292
    unconventional myosin complex 8.5646E-3 27 2 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    histone acetylation 1.1501E-23 27 36 13 6292
    protein amino acid acetylation 4.9607E-22 27 46 13 6292
    protein amino acid acylation 1.9202E-20 27 59 13 6292
    regulation of transcription involved in G1 phase of mitotic cell cycle 2.1872E-19 27 14 9 6292
    covalent chromatin modification 5.3612E-18 27 88 13 6292
    histone modification 5.3612E-18 27 88 13 6292
    G1 phase 4.9511E-16 27 27 9 6292
    G1 phase of mitotic cell cycle 4.9511E-16 27 27 9 6292
    post-translational protein modification 2.2664E-15 27 357 17 6292
    chromatin modification 3.196E-14 27 168 13 6292
    transcription initiation from RNA polymerase II promoter 1.3668E-13 27 47 9 6292
    chromatin organization 3.7773E-13 27 203 13 6292
    protein modification process 5.9873E-13 27 499 17 6292
    transcription initiation 1.0381E-12 27 58 9 6292
    macromolecule modification 5.1497E-12 27 569 17 6292
    cellular macromolecule metabolic process 5.8771E-11 27 2285 26 6292
    macromolecule metabolic process 1.1917E-10 27 2349 26 6292
    interphase of mitotic cell cycle 1.2587E-10 27 97 9 6292
    interphase 1.2587E-10 27 97 9 6292
    transcription from RNA polymerase II promoter 2.2397E-10 27 335 13 6292
    protein complex biogenesis 3.6259E-10 27 155 10 6292
    protein complex assembly 3.6259E-10 27 155 10 6292
    cellular protein metabolic process 1.2494E-9 27 1074 19 6292
    cellular metabolic process 2.6128E-9 27 3033 27 6292
    protein metabolic process 3.3475E-9 27 1136 19 6292
    metabolic process 7.7439E-9 27 3157 27 6292
    chromosome organization 1.0028E-8 27 555 14 6292
    regulation of transcription from RNA polymerase II promoter 1.5753E-8 27 228 10 6292
    primary metabolic process 2.4579E-8 27 2896 26 6292
    transcription, DNA-dependent 3.3065E-8 27 503 13 6292
    RNA biosynthetic process 3.7244E-8 27 508 13 6292
    transcription 1.0065E-7 27 552 13 6292
    macromolecular complex assembly 1.1567E-7 27 281 10 6292
    RNA metabolic process 1.7309E-7 27 954 16 6292
    mitotic cell cycle 6.3279E-7 27 255 9 6292
    cellular component organization 9.6176E-7 27 1582 19 6292
    macromolecular complex subunit organization 1.08E-6 27 357 10 6292
    regulation of transcription, DNA-dependent 1.1082E-6 27 358 10 6292
    regulation of RNA metabolic process 1.259E-6 27 363 10 6292
    regulation of transcription 2.1074E-6 27 384 10 6292
    cellular component assembly 2.158E-6 27 385 10 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.2653E-6 27 415 10 6292
    regulation of nitrogen compound metabolic process 4.3591E-6 27 416 10 6292
    regulation of cellular metabolic process 5.7068E-6 27 536 11 6292
    regulation of metabolic process 6.9561E-6 27 547 11 6292
    nucleic acid metabolic process 7.1603E-6 27 1415 17 6292
    regulation of gene expression 7.9885E-6 27 445 10 6292
    regulation of macromolecule biosynthetic process 9.9346E-6 27 456 10 6292
    gene expression 1.0742E-5 27 1283 16 6292
    organelle organization 1.1514E-5 27 1127 15 6292
    regulation of cellular biosynthetic process 1.3498E-5 27 472 10 6292
    regulation of biosynthetic process 1.3754E-5 27 473 10 6292
    cell cycle phase 1.5796E-5 27 376 9 6292
    regulation of macromolecule metabolic process 1.8125E-5 27 488 10 6292
    cellular macromolecule biosynthetic process 2.2156E-5 27 1187 15 6292
    macromolecule biosynthetic process 2.2629E-5 27 1189 15 6292
    regulation of primary metabolic process 2.8587E-5 27 514 10 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.0345E-5 27 1566 17 6292
    cellular nitrogen compound metabolic process 3.4144E-5 27 1770 18 6292
    nitrogen compound metabolic process 4.0669E-5 27 1791 18 6292
    cellular process 7.3243E-5 27 4426 27 6292
    cell cycle process 1.2855E-4 27 490 9 6292
    cellular biosynthetic process 1.49E-4 27 1567 16 6292
    biosynthetic process 1.9729E-4 27 1602 16 6292
    cell cycle 2.1842E-4 27 525 9 6292
    regulation of cellular process 2.3572E-4 27 796 11 6292
    regulation of biological process 3.2134E-4 27 824 11 6292
    cellular component biogenesis 3.6528E-4 27 694 10 6292
    biological regulation 2.4501E-3 27 1213 12 6292
    valyl-tRNA aminoacylation 4.2912E-3 27 1 1 6292
    endoplasmic reticulum inheritance 8.5646E-3 27 2 1 6292
    tRNA aminoacylation for protein translation 8.627E-3 27 33 2 6292
    tRNA aminoacylation 8.627E-3 27 33 2 6292
    amino acid activation 8.627E-3 27 33 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    transcription regulator activity 6.663E-13 27 339 15 6292
    general RNA polymerase II transcription factor activity 2.6432E-12 27 64 9 6292
    RNA polymerase II transcription factor activity 1.7789E-9 27 130 9 6292
    transcription cofactor activity 1.1986E-8 27 40 6 6292
    transcription factor binding 1.8874E-8 27 43 6 6292
    lysine N-acetyltransferase activity 4.6048E-5 27 17 3 6292
    histone acetyltransferase activity 4.6048E-5 27 17 3 6292
    transcription coactivator activity 8.9038E-5 27 21 3 6292
    N-acetyltransferase activity 3.5293E-4 27 33 3 6292
    N-acyltransferase activity 5.3794E-4 27 38 3 6292
    acetyltransferase activity 1.2077E-3 27 50 3 6292
    transcription activator activity 2.149E-3 27 61 3 6292
    coproporphyrinogen oxidase activity 4.2912E-3 27 1 1 6292
    valine-tRNA ligase activity 4.2912E-3 27 1 1 6292
    transferase activity, transferring acyl groups other than amino-acyl groups 6.8643E-3 27 92 3 6292
    acyltransferase activity 6.8643E-3 27 92 3 6292
    TATA-binding protein binding 8.5646E-3 27 2 1 6292
    methionine-tRNA ligase activity 8.5646E-3 27 2 1 6292
    RNA polymerase activity 9.142E-3 27 34 2 6292
    DNA-directed RNA polymerase activity 9.142E-3 27 34 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle