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A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. The chromatin modification process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype. Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. The alteration of DNA or protein in chromatin by the non-covalent addition or removal of chemical groups. The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups. The alteration of DNA or protein in chromatin, which may result in changing the chromatin structure.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: chromatin modification
Acc: GO:0016568
Aspect: Biological Process
Desc: The alteration of DNA or protein in chromatin, which may result in changing the chromatin structure.
Proteins in PDR annotated with:
   This term: 270 [Search]
   Term or descendants: 1197 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016568 - chromatin modification (interactive image map)
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