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Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met). Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of pyrophosphate and AMP. Catalysis of the ligation of two substances via a carbon-oxygen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate, to form aminoacyl-tRNA or a related compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: methionine-tRNA ligase activity
Acc: GO:0004825
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met).
Synonyms:
  • methionyl-transfer ribonucleate synthetase activity
  • methionyl-tRNA synthetase activity
  • MetRS activity
  • methionine translase activity
  • L-methionine:tRNAMet ligase (AMP-forming)
  • methionyl-transfer RNA synthetase activity
  • methionyl-transfer ribonucleic acid synthetase activity
Proteins in PDR annotated with:
   This term: 41 [Search]
   Term or descendants: 41 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0004825 - methionine-tRNA ligase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle