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Protein Overview: YNK1

General Information:
Name(s) found: YNK1 / YKL067W [SGD]
Description(s) found:
Found 31 descriptions.
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  • Nucleoside diphosphate kinase, catalyzes the transfer of gamma phosphates from nucleoside triphosphates, usually ATP, to nucleoside diphosphates by a mechanism that involves formation of an autophosphorylated enzyme intermediate [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 153 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial intermembrane space [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: RNA metabolic process [IDALink to PubMed article]
    purine nucleotide biosynthetic process [TASLink to PubMed article]
    nucleoside triphosphate biosynthetic process [IDALink to PubMed article]
    nucleoside diphosphate phosphorylation [IDALink to PubMed article]
    DNA metabolic process [IDALink to PubMed article]
    nucleotide metabolic process [TASLink to PubMed article]
    Molecular Function: nucleoside diphosphate kinase activity [IDALink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSQTERTFI AVKPDGVQRG LVSQILSRFE KKGYKLVAIK LVKADDKLLE QHYAEHVGKP  60
   61 FFPKMVSFMK SGPILATVWE GKDVVRQGRT ILGATNPLGS APGTIRGDFG IDLGRNVCHG 120
  121 SDSVDSAERE INLWFKKEEL VDWESNQAKW IYE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2006) ADE3 DPS1 FUR1 RPL30 SAR1 TDH1 YDR341C YNK1
    View Details Gavin AC, et al. (2002) HHF1, HHF2 RPA135 YNK1
    View Details Ho Y, et al. (2002) AAT2 ACH1 ACO1 AFR1 AHP1 ARC1 ARF1 ATP3 CAR2 CCT5 CDC15 CDC33 CLU1 CMD1 CMK2 CMP2 COF1 COR1 CPR1 CYR1 CYS4 DUG2 DUN1 EDE1 EGD1 ERG13 ERG6 FPR1 FRS2 GCD11 GND1 GND2 GRX1 GUS1 HCH1 HEF3 HHF1, HHF2 HYP2 ILS1 IPP1 LRO1 LSP1 MCX1 MET6 MYO2 MYO4 MYO5 NAP1 NMD3 NTF2 OLA1 OYE2 PFK1 PGM2 PIL1 PRM2 PRP19 PST2 QCR2 RNR2 RSN1 SAH1 SAR1 SCP160 SEC53 SEN15 SES1 SHE3 SNU13 SOD1 TCP1 TEF4 TEM1 THS1 TIF1, TIF2 TMA19 TSA2 UBA1 VAS1 VMA4 VMA5 VPS13 WTM1 YHR033W YJU2 YNK1
    View Details Qiu et al. (2008) ADK1 ADK2 STF2 YNK1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen FUN19 YNK1 1 Unpublished Fields Lab Data
    View Screen GBP2 YNK1 1 Unpublished Fields Lab Data
    View Screen YOL014W YNK1 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YNK1 Huh WK, et al. (2003)

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..153] PSI-BLAST 596.502279 Nucleoside diphosphate kinases


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle