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Protein Overview: RBG1

General Information:
Name(s) found: RBG1 / YAL036C [SGD]
Description(s) found:
Found 34 descriptions.
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  • Member of the DRG family of GTP-binding proteins; associates with translating ribosomes; interacts with Tma46p, Ygr250cp, Gir2p and Yap1p via two-hybrid [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 369 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: ribosome biogenesis [RCALink to PubMed article]
    Molecular Function: GTP binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTTVEKIKA IEDEMARTQK NKATSFHLGQ LKAKLAKLRR ELLTSASSGS GGGAGIGFDV  60
   61 ARTGVASVGF VGFPSVGKST LLSKLTGTES EAAEYEFTTL VTVPGVIRYK GAKIQMLDLP 120
  121 GIIDGAKDGR GRGKQVIAVA RTCNLLFIIL DVNKPLHHKQ IIEKELEGVG IRLNKTPPDI 180
  181 LIKKKEKGGI SITNTVPLTH LGNDEIRAVM SEYRINSAEI AFRCDATVDD LIDVLEASSR 240
  241 RYMPAIYVLN KIDSLSIEEL ELLYRIPNAV PISSGQDWNL DELLQVMWDR LNLVRIYTKP 300
  301 KGQIPDFTDP VVLRSDRCSV KDFCNQIHKS LVDDFRNALV YGSSVKHQPQ YVGLSHILED 360
  361 EDVVTILKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) CBF5 FUN12 KRE33 MAK5 RBG1 RPL15A RPS13 RPS1B RPS4B, RPS4A SBP1 SRO9 STM1 YGR054W
    View Details Krogan NJ, et al. (2006) HFM1 LYS4 NEW1 RBG1 SGD1 SOK1 SSZ1 TCB1 TGL5 TMA46 YEF3 YLR072W ZUO1
    View Details Gavin AC, et al. (2006) RBG1 TIF4631
    View Details Gavin AC, et al. (2002) ASC1 CBF5 CDC33 DBP2 HEK2 HHF1, HHF2 LHP1 MIS1 MRP7 NAB6 POL2 PUS7 RBG1 ROM2 SBP1 SNP1 SRO9 STM1 STO1 SUI3 TIF1, TIF2 TIF4631 TIF4632 UTP20 YMR310C
    View Details Ho Y, et al. (2002) CLU1 RBG1 RPN1 TIF1, TIF2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen RBG1 IES3 2 Unpublished Fields Lab Data
    View Screen RBG1 MED11 2 Unpublished Fields Lab Data
    View Screen RBG1 KAR3 2 Unpublished Fields Lab Data
    View Screen GIR2 RBG1 2 Unpublished Fields Lab Data
    View Screen RBG1 DAD1 2 Unpublished Fields Lab Data
    View Screen RBG1 SRB7 2 Unpublished Fields Lab Data
    View Screen RBG1 AHC1 1 Unpublished Fields Lab Data
    View Screen TWF1 RBG1 1 Unpublished Fields Lab Data
    View Screen RAD10 RBG1 1 Unpublished Fields Lab Data
    View Screen RBG1 RAD18 1 Unpublished Fields Lab Data
    View Screen RBG1 MET32 1 Unpublished Fields Lab Data
    View Screen RBG1 NKP1 1 Unpublished Fields Lab Data
    View Screen RBG1 TOM1 1 Unpublished Fields Lab Data
    View Screen RBG1 URB2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RBG1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..268] PSI-BLAST 33.69897 GTPase Era, N-terminal domain; GTPase Era C-terminal domain
    2 View Details [269..369] MSA 1.348996 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.09956015274464 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09345198747025 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  1.89320355239381 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  1.88721318481223 bayes_pls_golite062009
  • GTP binding
    		•  1.87900088157196 bayes_pls_golite062009
  • DNA binding
    		•  1.87765278833074 bayes_pls_golite062009
  • GTPase activity
    		•  1.23010905798386 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.21658213854831 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.21652144153182 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.21571071905795 bayes_pls_golite062009
  • nucleotide binding
    		•  1.20347573865566 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • motor activity
    		•  0.926612891775441 bayes_pls_golite062009
  • transcription factor activity
    		•  0.682439846757997 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.498311726132348 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.219555040684154 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.198256709027213 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.197994873032963 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.089234257580272 bayes_pls_golite062009
  • helicase activity
    		•  0.0775311459068899 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle